Novel tetrazole derivative useful as herbicides

ABSTRACT

Compounds of the Formula (I) wherein T represents a group, Q represents a group, R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , T 8 , R 9 , R 10 , R 11  are as defined in the description, m represents 0, 1, 2 or 3, n represents 0 or 1, A represents alkylene, processes for preparation, their intermediates and their use in agriculture are described.

The present invention relates to novel tetrazole derivatives, toprocesses for their preparation, to their intermediates and to their usein agriculture, especially to their use as herbicides.

It is known that certain tetrazole derivatives show herbicidal activity(cf. JP 12275/1999, JP 21280/1999 etc.). Further, it is known, thatcertain heterocyclic derivatives act as herbicide (JP 114769/2001, WO99/10327, WO 00/21924).

There have now been found novel tetrazole derivatives of the formula (I)

wherein

-   -   R¹ represents halogen, alkyl, haloalkyl, alkoxy, alkylthio,        alkylsulfonyl, alkylsulfonyloxy, alkoxyalkyl, alkylthioalkyl,        alkylsulfonylalkyl, nitro or cyano,    -   m represents 0, 1, 2 or 3,    -   R¹ may be identical or different to each other, when in        represents 2 or 3,    -   n represents 0 or 1,    -   A represents alkylene,    -   T represents a group        in which    -   R² represents hydrogen, alkyl or cycloalkyl, which may be        optionally substituted by alogen and alkyl, or        -   represents alkenyl, alkynyl, haloalkyl, alkylthio, or phenyl            which may be optionally substituted by halogen, alkyl,            haloalkyl and nitro, and    -   Q represents a group        wherein    -   R³ represents hydroxy, halogen or alkylcarbonyloxy, or        represents alkylthio which may be optionally substituted by        hydroxy, cyano, carboxy, alkoxycarbonyl and phenyl, or        -   represents 5- or 6-membered heteroarylthio containing 1-2            hetero atom(s) selected from the group consisting of            nitrogen, oxygen and sulfur, which may be optionally            substituted by halogen and alkyl, and when R³ represents            pyridylthio, said pyridylthio may form N-oxide, or        -   represents phenylthio which may be optionally substituted by            halogen, alkyl, alkoxy, haloalkyl and nitro, or represents            phenylcarbonyloxy which may be optionally substituted by            halogen and alkyl, or        -   represents 1-pyrazolyl which may be optionally substituted            or 1-imidazolyl which may be optionally substituted by            halogen and alkyl, or represents 1,2,4-triazol-1-yl or            1H-tetrazol-1-yl,    -   R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ each independently represent hydrogen        or alkyl, or    -   R⁴ may, together with R⁹, form an ethylene chain,    -   R¹⁰ represents alkyl, and    -   R¹¹ represents alkyl or cycloalkyl.

The compounds of the formula (I), according to the invention, can beobtained by a process in which

-   -   a) in case of preparing a compound of the formula (1) in which Q        represents the group (Q-1) and R³ represents hydroxy compounds        of the formula (II)        wherein    -   R¹, m, n, A and T have the same definition as aforementioned,        and    -   M¹ represents group        in which    -   R⁴, R⁵, R⁶, R⁷, R⁸, R⁹ and R¹⁰ have the same definition as        aforementioned,    -   are reacted to a rearrangement in the presence of inert        solvents, and if appropriate, in the presence of a base and a        cyanide, and if appropriate, in the presence of a phase-transfer        catalyst, or    -   b) in case of preparing a compound of the formula (I) in which Q        represents the group (Q-1) and R³ represents halogen, preferably        chloro or bromo: compounds of the formula (Ib)        wherein    -   R¹, m, n, A and T have the same definition as aforementioned,        and    -   Q_(b) represents group        in which    -   R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ have the same definition as        aforementioned,    -   are reacted with a halogenating agent in the presence of inert        solvents, or    -   c) in case of preparing a compound of the formula (I) in which        -   Q represents the group (Q-1) and        -   R³ represents alkylthio which may be optionally substituted            or            -   represents 5- or 6-membered heteroarylthio, or            -   represents phenylthio which may be optionally                substituted, or            -   represents 1-pyrazolyl which may be optionally                substituted or            -   represents 1-imidazolyl which may be optionally                substituted, or            -   represents 1,2,4-triazol-1-yl or 1H-tetrazol-1-yl:        -   compounds of the formula (1c)            wherein    -   R¹, m, n, A and T have the same definition as aforementioned,        and    -   Q_(c) represents group        in which    -   R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ have the same definition as        aforementioned, and    -   R^(3c) represents chloro or bromo,    -   are reacted with compounds of the formula (III)        R¹²—H   (III)        wherein    -   R¹² has the same definition as the above-mentioned R³ in the        preparation process (c),    -   in the presence of inert solvents, and if appropriate, in the        presence of an acid binding agent, or    -   d) in case of preparing a compound of the formula (I) in which Q        represents the group (Q-1) and R³ represents alkylcarbonyloxy or        phenylcarbonyloxy which may be optionally substituted:        -   compounds of the formula (Ib) are reacted with compounds of            the formula (IV)            wherein    -   R¹³ represents alkyl or phenyl which may be optionally        substituted, and    -   Hal represents halogen, preferably chloro or bromo,    -   in the presence of inert solvents, and if appropriate, in the        presence of an acid binding agent, or    -   e) in case of preparing a compound of the formula (I) in which Q        represents the group (Q-2):        -   compounds of the formula (IIe)            wherein    -   R¹, m, n, A and T have the same definition as aforementioned,        and    -   M² represents group        in which    -   R¹⁰ has the same definition as aforementioned,    -   are reacted to a rearrangement in the presence of inert        solvents,    -   and if appropriate, in the presence of a base, or    -   f) in case of preparing a compound of the formula (I) in which Q        represents the group (Q-3):    -   compounds of the formula (V)        wherein    -   R¹, m, n, A, T and R¹¹ have the same definition as        aforementioned, and    -   R¹⁴ represents C₁₋₄ alkyl, preferably methyl or ethyl,    -   are reacted with hydroxylamine in the presence of inert        solvents, and if appropriate, in the presence of a base, or    -   g) in case of preparing a compound of the formula (I) in which Q        represents the group (Q-4):        -   compounds of the formula (Ig)            wherein    -   R¹, m, n, A, T and R¹¹ have the same definition as        aforementioned,    -   are reacted to a ring—opening in the presence of inert solvents,        and if appropriate, in the presence of a base.

The tetrazole derivatives of the formula (I) provided by the presentinvention show a strong herbicidal action. The compounds of the formula(I) of the present invention unexpectedly show an extremely strongherbicidal action compared with the known compounds disclosed in theabove-mentioned state of the art. They particularly show an extremelygood effect as a selective herbicide for paddy rice that shows excellentherbicidal action against paddy field weeds and has no substantialphytotoxicity to paddy rice. The compound of the formula (I) show aneven stronger herbicidal action it they are mixed with other herbicidalcompounds or safeners as specifically mentioned later.

In the formulae used herein the following definitions are used unlessotherwise specified:

“Halogen” represents fluoro, chloro, bromo or iodo, preferablyrepresents fluoro, chloro or bromo.

“Alkyl” can be straight-chain or branched-chain. Alkyl preferablyrepresents C₁₋₆ alkyl, and particularly preferably methyl, ethyl, n- oriso-propyl, n-, iso-, sec- or tert-butyl, n-, iso-, neo- or tert-pentyl,n- or iso-hexyl.

“Cycloalkyl” represents a cyclyc hydrocarbon moiety. It preferablyrepresents cyclopropyl, cyclobutyl, cyclopentyl, cyclohexyl etc. Thesecycloalkyls may be optionally substituted by halogen or alkyl. When aplurality of substituents exist, they may be identical or different. Asspecific examples of such substituted cycloalkyl there can be mentioned1-methylcyclopropyl, 1-ethylcyclopropyl, 1-n-propylcyclopropyl,1-methyl-2-fluorocyclopropyl, 2-methylcyclopropyl, 2-fluoro-cyclopropyl,1-methyl-2,2-difluorocyclopropyl, 1-methyl-2,2-dichlorocyclopropyl,2,2-difluorocyclopropyl, 2-methylcyclopentyl, 1-methylcyclohexyl,2-methyl-cyclohexyl, 3-methylcyclohexyl, 4-methylcyclohexyl,2,3-dimethylcyclohexyl, 2,6-dimethylcyclohexyl, 2,5-dimethylcyclohexyland so on.

“Alkenyl” represents a straight-chain or branched-chain hydrocarbonmoiety having one or more carbon-carbon double bonds. It preferablyrepresents vinyl, allyl, 1-methylallyl, 1,1-dimethylallyl, 2-butenyl,2-pentenyl, 2-hexenyl and so on.

“Alkynyl” represents a straight-chain or branched-chainhydrocarbon-moiety having one or more carbon-carbon triple bonds,ethynyl, 2-propynyl, 1-methyl-2-propynyl, 1,1-dimethyl-2-propynyl,2-butynyl, 2-pentynyl, 2-hexynyl and so on.

“Alkylene” can be straight-chain or branched-chain and includes, forexample, methylene, ethylidene, ethylene, propylidene, methylethylene(propylene), trimethylene, ethylethylene, methyltrimethylene,2-methyltrimethylene, tetramethylene and so on.

“Alkoxy” represents an Alkyl-O— group, whose alkyl part has theabove-mentioned meaning. It preferably represents C₁₋₆ alkoxy, andparticularly preferably methoxy, ethoxy, n- or iso-propoxy, n-, iso-,sec- or tert-butoxy, n-pentyloxy, n-hexyloxy.

“Alkylthio” represents an Alkyl-S— group, whose alkyl part has theabove-mentioned meaning. It preferably represents C₁₋₆ alkylthio, andparticularly preferably methylthio, ethylthio, n- or iso-propylthio, n-,iso-, sec- or tert-butylthio, n-pentylthio, n-hexylthio.

“Alkylsulfonyl” represents an Alkyl-SO₂— group, whose alkyl part has theabove-mentioned meaning. It preferably represents C₁₋₆ alkylsulfonyl,and particularly preferably methylsulfonyl, ethylsulfonyl, n- oriso-propylsulfonyl, n-, iso-, sec- or tert-butylsulfonyl.

“Alkylsulfonyloxy” represents an Alkyl-SO₂—O— group, whose alkyl parthas the above-mentioned meaning. It preferably represents C₁₋₄alkylsulfonyloxy, and particularly preferably methylsulfonyloxy,ethylsulfonyloxy, n- or iso-propyl-sulfonyloxy, n-, iso-, sec- ortert-butylsulfonyloxy.

“Alkylcarbonyl” represents an Alkyl-CO— group, whose alkyl part has theabove-mentioned meaning. It preferably represents C₁₋₆ alkylcarbonyl,and particularly preferably acetyl, propionyl, butyryl, isobutyryl,valeryl, isovaleryl, pivaloyl, n-pentylcarbonyl, n-hexylcarbonyl.

“Alkylcarbonyloxy” represents an Alkyl-CO₂— group, whose alkyl part hasthe above-mentioned meaning. It preferably represents C₁₋₆alkylcarbonyloxy, and particularly preferably acetoxy, ethylcarbonyloxy,n- or iso-propylcarbonyloxy, n-, iso-, sec- or tert-butylcarbonyloxy,n-pentylcarbonyloxy, n-hexylcarbonyloxy.

“Alkoxyalkyl” represents alkyl substituted with alkoxy. It preferablyrepresents C_(2-≢)(total carbon number) alkoxyalkyl, and particularlypreferably methoxymethyl, 1-methoxyethyl, 2-methoxyethyl,2-methoxy-1-methylethyl, methoxypropyl, methoxybutyl, methoxypentyl,ethoxymethyl, n- or iso-propoxymethyl, n-, iso-, sec- ortert-butoxymethyl.

“Alkylthioalkyl” represents alkyl substituted with alkylthio. Itpreferably represents C₂₋₆ (total carbon number) alkylthioalkyl, andparticularly preferably methylthiomethyl, methylthioethyl,1-methylthiopropyl, 2-methylthiopropyl, 1-methyl-2-methylthioethyl,methylthiobutyl, methylthiopentyl, ethylthiomethyl, n- oriso-propylthiomethyl, n-, iso-, sec- or tert-butylthiomethyl.

“Alkylsulfonylalkyl” represents alkyl substituted with alkylsulfonyl. Itpreferably represents C₂₋₆ (total carbon number) alkylsulfonylalkyl, andparticularly preferably methylsulfonylmethyl, methylsulfonylethyl,1-methylsulfonylpropyl, 2-methylsulfonylpropyl,1-methyl-2-methylsulfonylethyl, methylsulfonylbutyl,methylsulfonylpentyl, ethylsulfonylmethyl, n- oriso-propylsulfonylmethyl, n-, iso-, sec- or tert-butylsulfonylmethyl.

“Haloalkyl” represents straight-chain or branched-chain alkyl, in whichat least one hydrogen is halogen-substituted. It preferably representsC₁₋₄ alkyl substituted with 1-6 fluoro and/or chloro, difluoromethyl,trifluoromethyl, 2,2,2-trifluoroethyl, dichloromethyl,2-chloro-1,1,2-trifluoroethyl, 3-fluoropropyl, 3-chloropropyl,2,2,3,3,3-pentafluoropropyl, 1,2,2,3,3,3-hexafluoropropyl.

The haloalkyl part in “haloalkoxy” can be of the same definition as inthe above-mentioned “haloalkyl”. It particularly preferably representsdifluoromethoxy, trifluoromethoxy, 2-fluoroethoxy, 2-chloroethoxy,2-bromoethoxy, 2,2,2-trifluoroethoxy, 3-chloropropoxy and so on.

As “5- or 6-membered heteroarylthio containing 1-2 hetero atom(s)selected from the group consisting of nitrogen, oxygen and sulfur” therecan be mentioned, for example, thienylthio, thiazolylthio, oxazolylthio,pyridylthio, pyrimidylthio and so on. In case of pyridylthio, saidpyridylthio can form an N-oxide.

Preferred substituents or preferred ranges of the radicals present inthe formulae listed above and below are defined as follows:

-   -   R¹ preferably represents fluoro, chloro, bromo, iodo, C₁₋₆        alkyl, C₁₋₆ haloalkyl, C₁₋₆ alkoxy, C₁₋₄ alkylthio, C₁₋₆        alkylsulfonyl, C₁₋₆ alkylsulfonyloxy, C₂₋₆ alkoxyalkyl, C₂₋₆        alkylthioalkyl, C₂₋₆ alkylsulfonylalkyl, nitro or cyano.    -   m preferably represents 2 or 3.    -   A preferably represents C₁₋₄ alkylene.    -   R² preferably represents hydrogen, C₁₋₆ alkyl, C₃₋₆ cycloalkyl,        C₂₋₆ alkenyl, C₂₋₆ alkynyl, C₁₋₆ haloalkyl, C₁₋₆ alkylthio, or        phenyl which may be optionally substituted by chloro, C₁₋₄        alkyl, C₁₋₄ haloalkyl and nitro.    -   R³ preferably represents hydroxy, chloro, bromo, C₂₋₅        alkylcarbonyloxy, or C₁₋₆ alkylthio which may be optionally        substituted by hydroxy, cyano, carboxy, C₂₋₅ alkoxycarbonyl and        phenyl, or        -   thienylthio, thiazolylthio, oxazolylthio, pyridylthio,            1-oxidopyridylthio or pyrimidylthio, optionally substituted            by chloro-, bromo-, or C₁-C₄ alkyl, or phenylthio which may            be optionally substituted by one or two substituents            selected from the group consisting of fluoro, chloro, bromo,            C₁₋₄ alkyl, C₁₋₄ alkoxy, C₁₋₄ haloalkyl and nitro, or        -   phenylcarbonyloxy which may be optionally substituted by one            or two substituents selected from the group consisting of            chloro and C₁₋₄ alkyl, or 1-pyrazolyl or 1-imidazolyl which            may be optionally substituted by one or two substituents            selected from the group consisting of chloro, bromo and C₁₋₄            alkyl, or        -   1,2,4-triazol-1-yl or 1H-tetrazol-1-yl.    -   R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ each independently preferably        represent hydrogen or C₁₋₄ alkyl, or    -   R⁴ may, together with R⁹, form an ethylene chain.    -   R¹⁰ preferably represents C₁₋₄ alkyl.    -   R¹¹ preferably represents C₃₋₆ cycloalkyl.    -   R¹ particularly preferably represents chloro, bromo, methyl,        trifluoromethyl, methoxy, methylthio, ethylthio, methylsulfonyl,        ethylsulfonyl, n-propylsulfonyl, methylsulfonyloxy,        methoxymethyl, methylthiomethyl, methylsulfonylmethyl, nitro or        cyano.    -   m particularly preferably represents 2,    -   A particularly preferably represents C₁₋₄ alkylene.    -   R² particulary preferably represents hydrogen, methyl, ethyl,        n-propyl, cyclopropyl, cyclopentyl, vinyl, allyl, ethynyl,        trifluoromethyl, 2-chloroethyl, 3-bromopropyl, methylthio,        ethylthio, n-propylthio, or phenyl which may be optionally        substituted by chloro, methyl, ethyl, n-propyl, trifluoromethyl        and nitro.    -   R³ particularly preferably represents hydroxy, chloro, acetoxy,        tert-butyl-carbonyloxy, methylthio, ethylthio, n-propylthio,        2-hydroxyethylthio, 2-cyanoethylthio, carboxymethylthio,        methoxycarbonylmethylthio, 2-(ethoxy-carbonyl)ethylthio,        benzylthio, or        -   2-thienylthio, 2-thiazolylthio, 2-oxazolylthio,            2-pyridylthio, 1-oxido-2-pyridylthio or 2-pyrimidylthio,            optionally substituted by one or more substituents selected            from the group consisting of chloro and methyl, or            phenylthio which may be optionally substituted by a            substituent selected from the group consisting of fluoro,            chloro, methyl, ethyl, n-propyl, methoxy, trifluoromethyl            and nitro, or        -   represents phenylcarbonyloxy which may be optionally            substituted by a substituent selected from the group            consisting of chloro and methyl, or        -   represents1-pyrazolyl or 1-imidazolyl which may be            optionally substituted by one or two substituents selected            from the group consisting of chloro and methyl, or        -   represents 1,2,4-triazol-1-yl or 1H-tetrazol-1-yl.    -   R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ each independently, particularly        preferably represent hydrogen or methyl, or    -   R⁴ may, together with R⁹, form an ethylene chain.    -   R¹⁰ particularly preferably represents methyl or ethyl.    -   R¹¹ particularly preferably represents cyclopropyl.

Compounds of the formula (I-1)

in which R¹, R³, R⁴, R⁵, R⁶, R⁷, R⁸, R⁹, m, n, A, T are each as definedabove are particularly emphasised as being part of the invention.

Compounds of the formula (I-2)

in which R¹, R¹⁰, m, n, A, T are each as defined above are particularlyemphasised as being part of the invention.

Compounds of the formula (I-3)

in which R¹, R¹¹, m, n, A, T are each as defined above are particularlyemphasised as being part of the invention.

Compounds of the formula (I-4)

in which R¹, R¹¹, m, n, A, T are each as defined above are particularlyemphasised as being part of the invention.

The abovementioned general or preferred radical definitions apply bothto the end products of the formula (I) and also, correspondingly, to thestarting materials or intermediates required in each case for thepreparation. These radical definitions can be combined with one anotherat will, i.e. including combinations between the given preferred ranges.

Preference according to the invention is given to compounds of theformula (I) which contain a combination of the meanings mentioned aboveas being preferred.

Particular preference according to the invention is given to compoundsof the formula (I) which contain a combination of the meanings listedabove as being particularly preferred.

Very particular preference according to the invention is given to thecompounds of the formula (I) which contain a combination of the meaningslisted above as being very particularly preferred.

Process (a) can be illustrated by the following reaction formula when,for example, 3-oxo-1-cyclohexenyl2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoate and acetonecyanohydrin, as a cyanide, are used as the starting materials.

Pprocess (b) can be illustrated by the following reaction formula when,for example,2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}cyclohexan-1,3-dioneand, for example, oxalyl dichloride, as a chlorinating agent, are usedas the starting materials.

Process(c) can be illustrated by the following reaction formula when,for example,3-chloro-2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}-2-cyclohexen-1-oneand thiophenol are used as the starting materials.

Process(d) can be illustrated by the following reaction formula when,for example,2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}-2-cyclohexan-1,3-dioneand benzoyl chloride are used as the starting materials.

Process(e) can be illustrated by the following reaction formula when,for example,5-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyloxy}-1-ethylpyrazole,and, for example, triethylamine as a base, are used as the startingmaterials.

Process(f) can be illustrated by the following reaction formula when,for example,3-cyclopropyl-1-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]phenyl}-2-ethoxymethylenepropan-1,3-dioneand hydroxylamine are used as the starting materials.

Process(g) can be illustrated by the following reaction formula when,for example,5-cyclopropyl-4-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}isoxazole,and, for example, triethylamine as a base, are used as the startingmaterials.

In case Q represents (Q-1) and R³ represents hydroxy in formula (I),this group has tautomers, as shown in the following (Q-1a), (Q-1b) and(Q-1c).

Consequently, when group Q represents the group (Q-1) and R³ representshydroxy in compounds of the formula (I) of the present invention, thecompounds of the formula (I) of the present invention can exist as atautomers.

The compounds of the formula (II), starting material in theabove-mentioned preparation process (a), are novel compounds. Compound(II) can be prepared by the process described in JP 222/1990, JP173/1990, JP 6425/1990 etc., namely by reacting compounds of the formula(VI)

wherein

-   -   R¹, m, n, A and T have the same definition as aforementioned,        and    -   Hal represents halogen, preferably chloro or bromo,    -   with compounds of the formula (VII)        M¹-H   (VII)        wherein    -   M¹ has the same definition as aforementioned,    -   in an appropriate diluent, for example, dichloromethane in the        presence of an appropriate condensing agent, for example,        triethylamine.

The compounds of the above-mentioned formula (VI) include the knowncompounds described in U.S. Pat. No. 6,194,406, WO 97/22604 and can beprepared, for example, by reacting compounds of the formula (VIII)

wherein

-   -   R¹, m, n, A and T have the same definition as aforementioned,    -   with a halogenating agent, for example, phosphorus oxychloride,        phosphorus oxybromide, phosphorus trichloride, phosphorus        tribromide, phosgene, oxalyl dichloride, thionyl chloride,        thionyl bromide etc.

On the other hand, the compounds of the above-mentioned formula (VII)used as the starting materials in the preparation of the compounds ofthe above-mentioned formula (II) are per se known, can be obtained onthe market, or can be prepared according to the process described inknown literatures, (e.g. JP 6425/1990, JP 265415/1998, JP 265441/1998,JP 257974/1986 etc.

The compounds of the above-mentioned formula (VIII) include the knowncompounds described in U.S. Pat. No. 6,194,406, WO 97/22604 and can beeasily prepared, for example, by hydrolyzing compounds of the formula(IX)

wherein

-   -   R¹, m, n, A, T and R¹⁴ have the same definition as        aforementioned,    -   in an appropriate diluent, for example, hydrous dioxane, in the        presence of an appropriate base, for example, sodium hydroxide.

The compounds of the above-mentioned formula (IX) include the knowncompounds described in U.S. Pat. No. 6,194,406, WO 97/22604 and can beeasily prepared, for example, by reacting compounds of the formula (X)T-H   (X)wherein

-   -   T has the same definition as aforementioned,        -   with compounds of the formula (XI)            wherein    -   R¹, m, n, A, Hal and R¹⁴ have the same definition as        aforementioned,    -   in an appropriate diluent, for example, N,N-dimethylformamide,        in the presence of an appropriate condensing agent, for example,        potassium carbonate.

The compounds of the above-mentioned formula (X) are known.

The compounds of the above-mentioned formula (XI) include the knowncompounds described in JP 173/1990, JP 247891/1994, JP 206808/1995 andcan be easily prepared, for example, by the processes described in theabove-mentioned publications.

The compounds of the formula (II), the starting materials in theabove-mentioned preparation process (a), can be prepared also from thecompounds of the formula (XIII) by the process described in WO 93/18031.

As typical examples of the compounds of the formula (II) used as thestarting materials in Process(a) the following can be mentioned:

-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[(5-methyl-tetrazol-1-yl)methyl]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[(5-methyl-tetrazol-2-yl)methyl]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dibromo-3-[(1H-tetrazol-1-yl)methyl]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dibromo-3-[(2H-tetrazol-2-yl)methyl]benzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[(5-phenyl-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[(5-phenyl-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[(5-methylthio-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[(5-methylthio-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoate,-   4-{2,4-dichloro-3-[(5-methyl-tetrazol-1-yl)methyl]benzoyloxy}bicyclo[3.2.1]-3-octen-2-one,-   4-{2,4-dichloro-3-[(5-methyl-tetrazol-2-yl)methyl]benzoyloxy}bicyclo[3.2.1]-3-octen-2-one,-   3-oxo-1-cycloheptanyl    2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoate,-   3-oxo-1-cycloheptanyl    2-chloro-3-[(1H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoate,-   5-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyloxy}-1-methylpyrazole,-   5-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyloxy}-1-methylpyrazole,-   5-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,-   5-{2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyl]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyl]benzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(5-methyl-tetrazol-1-yl)propyloxy]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(5-methyl-tetrazol-2-yl)propyloxy]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[3-(1H-tetrazol-1-yl)propyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[3-(2H-tetrazol-2-yl)propyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[3-(2H-tetrazol-2-yl)ethyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[2-(5-methyl-tetrazol-1-yl)ethyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dichloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dibromo-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2,4-dibromo-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(5-phenyl-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(5-phenyl-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(5-methylthio-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoate,-   3-oxo-1-cyclohexenyl    2-chloro-3-[2-(5-methylthio-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoate,-   4-{2,4-dichloro-3-[2-(5-methyl-tetrazol-1-yl)ethyloxy]benzoyloxy}bicyclo[3.2.1]-3-octen-2-one,-   4-{2,4-dichloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]benzoyloxy}bicyclo[3.2.1]-3-octen-2-one,-   3-oxo-1-cycloheptanyl    2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoate,-   3-oxo-1-cycloheptanyl    2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoate,-   5-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyloxy}-1-methylpyrazole,-   5-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyloxy}-1-methylpyrazole,-   5-{2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,-   5-{2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,    etc.

As typical examples of the compounds of the formula (VI) used as thestarting materials in the preparation of the compounds of the formula(II) the following can be mentioned:

-   2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyl chloride,-   2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyl chloride,-   2,4-dichloro-3-[(5-methyl-tetrazol-1-yl)methyl]benzoyl chloride,-   2,4-dichloro-3-[(5-methyl-tetrazol-2-yl)methyl]benzoyl chloride,-   2,4-dibromo-3-[(1H-tetrazol-1-yl)methyl]benzoyl chloride,-   2,4-dibromo-3-[(2H-tetrazol-2-yl)methyl]benzoyl chloride,-   2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[(5-methyl-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[(5-methyl-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[(5-methylthio-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[(5-methylthio-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl    chloride,-   2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl chloride,-   2,4-dichloro-3-[2-(1H-tetrazol-2-yl)ethyloxy]benzoyl chloride,-   2,4-dichloro-3-[2-(5-methyl-tetrazol-1-yl)ethyloxy]benzoyl chloride,-   2,4-dichloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]benzoyl chloride,-   2,4-dichloro-3-[2-(5-methylthio-tetrazol-1-yl)ethyloxy]benzoyl    chloride,-   2,4-dichloro-3-[2-(5-methylthio-tetrazol-2-yl)ethyloxy]benzoyl    chloride,-   2,4-dibromo-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl chloride,-   2,4-dibromo-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl chloride,-   2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[2-(5-methyl-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyl    chloride,-   2-chloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyl    chloride, etc.

As typical examples of the compounds of the formula (VIII) used as thestarting materials in the preparation of the compounds of the formula(VI) the following can be mentioned:

-   2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoic acid,-   2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoic acid,-   2,4-dichloro-3-[(5-methyl-tetrazol-1-yl)methyl]benzoic acid,-   2,4-dichloro-3-[(5-methyl-tetrazol-2-yl)methyl]benzoic acid,-   2,4-dibromo-3-[(1H-tetrazol-1-yl)methyl]benzoic acid,-   2,4-dibromo-3-[(2H-tetrazol-2-yl)methyl]benzoic acid,-   2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoic acid,-   2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoic acid,-   2-chloro-3-[(5-methyl-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoic    acid,-   2-chloro-3-[(5-methyl-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoic    acid,-   2-chloro-3-[(5-methylthio-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoic    acid,-   2-chloro-3-[(5-methylthio-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoic    acid,-   2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoic acid,-   2,4-dichloro-3-[2-(1H-tetrazol-2-yl)ethyloxy]benzoic acid,-   2,4-dichloro-3-[2-(5-methyl-tetrazol-1-yl)ethyloxy]benzoic acid,-   2,4-dichloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]benzoic acid,-   2,4-dichloro-3-[2-(5-methylthio-tetrazol-1-yl)ethyloxy]benzoic acid,-   2,4-dichloro-3-[2-(5-methylthio-tetrazol-2-yl)ethyloxy]benzoic acid,-   2,4-dibromo-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoic acid,-   2,4-dibromo-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoic acid,-   2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoic    acid,-   2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoic    acid,-   2-chloro-3-[2-(5-methyl-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoic    acid,-   2-chloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoic    acid, etc.

As typical examples of the compounds of the formula (IX) used as thestarting materials in the preparation of the compounds of the formula(VIII) the following can be mentioned:

-   methyl 2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoate,-   methyl 2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoate,-   methyl 2,4-dichloro-3-[(5-methyl-tetrazol-1-yl)methyl]benzoate,-   methyl 2,4-dichloro-3-[(5-methyl-tetrazol-2-yl)methyl]benzoate,-   methyl 2,4-dibromo-3-[(1H-tetrazol-1-yl)methyl]benzoate,-   methyl 2,4-dibromo-3-[(2H-tetrazol-2-yl)methyl]benzoate,-   methyl    2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoate,-   methyl    2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoate,-   methyl    2-chloro-3-[(5-methyl-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoate,-   methyl    2-chloro-3-[(5-methyl-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoate,-   methyl    2-chloro-3-[(5-methylthio-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoate,-   methyl    2-chloro-3-[(5-methylthio-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoate,-   ethyl 2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoate,-   ethyl 2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoate,-   ethyl 2,4-dichloro-3-[2-(5-methyl-tetrazol-1-yl)ethyloxy]benzoate,-   ethyl 2,4-dichloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]benzoate,-   ethyl    2,4-dichloro-3-[2-(5-methylthio-tetrazol-1-yl)ethyloxy]benzoate,-   ethyl    2,4-dichloro-3-[2-(5-methylthio-tetrazol-2-yl)ethyloxy]benzoate,-   ethyl 2,4-dibromo-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoate,-   ethyl 2,4-dibromo-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoate,-   ethyl    2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoate,-   ethyl    2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoate,-   ethyl    2-chloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoate,-   ethyl    2-chloro-3-[2-(5-methyl-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoate,    etc.

The compounds of the formula (Ib), the starting materials in Process(b),are a part of the formula (I) of the present invention and can be easilyprepared according to the above-mentioned preparation process (a).

As typical examples of the compounds of the formula (Ib) used as thestarting materials in Process(b) the following compounds, which areincluded in the formula (1), can be mentioned:

-   2-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyl}cyclohexane-1,3-dione,-   2-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyl}cyclohexane-1,3-dione,-   2-{2,4-dibromo-3-[(5-methyl-tetrazol-1-yl)methyl]benzoyl}cyclohexane-1,3-dione,-   2-{2,4-dibromo-3-[(5-methyl-tetrazol-2-yl)methyl]benzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[(1H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[(5-methylthio-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[(5-methylthio-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   3-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl}bicyclo[3.2.1]-octane-2,4-dione,-   3-{2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl}bicyclo[3.2.1]-octane-2,4-dione,-   2-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyl}cycloheptane-1,3-dione,-   2-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyl}cycloheptane-1,3-dione,-   2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl}cyclohexane-1,3-dione,-   2-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl}cyclohexane-1,3-dione,-   2-{2,4-dibromo-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl}cyclohexane-1,3-dione,-   2-{2,4-dibromo-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[2-(5-methylthio-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   2-{2-chloro-3-[2-(5-methylthio-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyl}cyclohexane-1,3-dione,-   3-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl}bicyclo[3.2.1]-octane-2,4-dione,-   3-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl}bicyclo[3.2.1]-octane-2,4-dione,-   2-{2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyl}cycloheptane-1,3-dione,-   2-{2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyl}cycloheptane-1,3-dione,    etc.

As halogenating agents used for the reaction with the compounds of theformula (Ib) in the preparation process (b) there can be mentioned, forexample, thionyl chloride, thionyl bromide, oxalyl dichloride, oxalyldibromide etc.

The compounds of the formula (Ic), the starting materials in Process(c),are a part of the formula (I) of the present invention and can be easilyprepared according to the above-mentioned preparation process (a).

As typical examples of the compounds of the formula (Ic) used asstarting materials in Process(c) the following compounds, which areincluded in the formula (I), can be mentioned:

-   3-chloro-2-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2,4-dibromo-3-[(5-methyl-tetrazol-1-yl)methyl]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2,4-dibromo-3-[(5-methyl-tetrazol-2-yl)methyl]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[(5-methylthio-tetrazol-1-yl)methyl]-4-methylsulfonyl-benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[(5-methylthio-tetrazol-2-yl)methyl]-4-methylsulfonyl-benzoyl}-2-cyclohexen-1-one,-   4-chloro-3-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl}bicyclo[3.2.1]-3-octen-1-one,-   4-chloro-3-{2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl}bicyclo[3.2.1]-3-octen-1-one,-   3-chloro-2-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyl}-2-cyclohepten-1-one,-   3-chloro-2-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyl}-2-cyclohepten-1-one,-   3-chloro-2-{2,4-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2,4-dibromo-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2,4-dibromo-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[2-(5-methylthio-tetrazol-1-yl)ethyloxy]-4-methylsulfonyl-benzoyl}-2-cyclohexen-1-one,-   3-chloro-2-{2-chloro-3-[2-(5-methylthio-tetrazol-2-yl)ethyloxy]-4-methylsulfonyl-benzoyl}-2-cyclohexen-1-one,-   4-chloro-3-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl}bicyclo[3.2.1]-3-octen-2-one,-   4-chloro-3-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl}bicyclo[3.2.1]-3-octen-2-one,-   3-chloro-2-{2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyl}-2-cyclohepten-1-one,-   3-chloro-2-{2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyl}cyclohepten-1-one,    etc.

The compounds of the formula (IV), the starting materials in Process(d),are carbonyl halides well known in the field of organic chemistry. Astheir specific examples the following can be mentioned:

-   -   acetyl chloride,    -   propionyl chloride, isobutyryl chloride, pivaloyl chloride,        benzoyl chloride, 2-methylbenzoyl chloride, 2,6-dichlorobenzoyl        chloride, 2,6-dimethylbenzoyl chloride, etc.

The compounds of the formula (IIe), the starting materials inProcess(c), are a part of the formula (II) and can be easily preparedaccording to the above-mentioned.

As typical examples of the compounds of the formula (IIe) the followingcompounds, which are included in the formula (II), can be mentioned:

-   5-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyloxy}-1-methylpyrazole,-   5-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyloxy}-1-methylpyrazole,-   5-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,-   5-{2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,-   5-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyloxy}-1-methylpyrazole,-   5-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyloxy}-1-methylpyrazole,-   5-{2-chloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,-   5-{2-chloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]-4-methylsulfonylbenzoyloxy}-1-ethylpyrazole,    etc.

The compounds of the formula (V), the starting materials in theabove-mentioned preparation process (f), are novel. They can be preparedby the process described in JP 202008/1993, namely by reacting compoundsof the formula (XII)

wherein

-   -   R¹, m, n, A, T and R¹¹ have the same definition as        aforementioned,    -   with compounds of the formula (XI)        HC(OR¹⁴)₃   (XIII)        wherein    -   R¹⁴ has the same definition as aforementioned,    -   in an appropriate diluent, for example, acetic anhydride.

The compounds of formula (XII) are novel compounds. Compounds (XII) canbe prepared by the process described in JP 202008/1993, namely byconducting a refluxing treatment of a compound of the formula (XIV)

wherein

-   -   R¹, m, n, A, T, R¹¹ and R¹⁴ have the same definition as        aforementioned,    -   in an appropriate diluent, for example, toluene under an        appropriate acidic condition, for example, in the presence of        p-toluenesulfonic acid monohydrate.

The compounds of formula (XIV) are novel compounds. Compounds (XIV) canbe prepared by the process described in JP 202008/1993, namely byreacting a compound represented by formula (VI) with, for example, acomplex obtained by treating a compound represented by the formula (XV)

wherein

-   -   R¹¹ and R¹⁴ have the same definition as aforementioned,    -   with magnesium and carbon tetrachloride.

The compounds of the above-mentioned formula (XV) are available on themarket and can be also prepared according to the process described in,for example, Journal of Organic Chemistry, Vol. 43, 2087 (1978).

As typical examples of the compounds of the formula (V) used as thestarting materials in Process(f) the following can be mentioned:

-   3-cyclopropyl-1-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]phenyl}-2-ethoxypropane-1,3-dione,-   3-cyclopropyl-1-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]phenyl}-2-ethoxypropane-1,3-dione,-   3-cyclopropyl-1-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylphenyl}-2-ethoxypropane-1,3-dione,-   3-cyclopropyl-1-{2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylphenyl}-2-ethoxypropane-1,3-dione,-   3-cyclopropyl-1-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]phenyl}-2-ethoxy-propane-1,3-dione,-   3-cyclopropyl-1-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]phenyl}-2-ethoxypropane-1,3-dione,    etc.

The compounds of the formula (Ig), the starting materials in Process(g),are a part of the formula (I) of the present invention and can be easilyprepared according to the above-mentioned preparation process (f).

As typical examples of the compounds of the formula (Ig) used as thestarting materials in Process(g) the following compounds, which areincluded in the formula (I), can be mentioned:

-   5-cyclopropyl-4-{2,4-dichloro-3-[(1H-tetrazol-1-yl)methyl]benzoyl}isoxazole,-   5-cyclopropyl-4-{2,4-dichloro-3-[(2H-tetrazol-2-yl)methyl]benzoyl}isoxazole,-   5-cyclopropyl-4-{2-chloro-3-[(1H-tetrazol-1-yl)methyl]-4-methylsulfonylbenzoyl}isoxazole,-   5-cyclopropyl-4-{2-chloro-3-[(2H-tetrazol-2-yl)methyl]-4-methylsulfonylbenzoyl}isoxazole,-   5-cyclopropyl-4-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethyloxy]benzoyl}isoxazole,-   5-cyclopropyl-4-{2,4-dichloro-3-[2-(2H-tetrazol-2-yl)ethyloxy]benzoyl}isoxazole,    etc.

The compounds of the formulae (II), (V), (XII) and (XV) are eitherstarting materials or intermediates in the processes (a)-(g), forpreparing compounds of the formula (I). They are novel compounds and arerepresented collectively by formula (XVI)

wherein

-   -   R¹, m, n, A and T have the same definition as aforementioned,        and    -   Z represents group        in which    -   R⁴, R⁵, R⁶, R⁷, R⁸, R⁹, R¹⁰, R¹¹ and R¹⁴ have the same        definition as aforementioned.

The reaction of process (a) can be conducted in an appropriate diluent.As the diluent used in that case there can be mentioned, for example,aliphatic, alicyclic and aromatic hydrocarbons (which may be optionallychlorinated), for example, toluene, dichloromethane, chloroform,1,2-dichloroethane etc.; ethers, for example, ethyl ether,dimethoxyethane (DME), tetrahydrofuran (THF) etc.; ketones, for example,methyl isobutyl ketone (MIBK) etc.; nitriles, for example, acetonitrileetc.: esters, for example, ethyl acetate etc.; acid amides, for example,dimethylformamide (DMF) etc.

The process (a) can be conducted in the presence of a cyanide and a baseand as the cyanide usable in that case there can be mentioned, forexample, sodium cyanide, potassium cyanide, acetone cyanohydrin,hydrogen cyanide etc. As the base there can be mentioned, for example,as inorganic base, hydroxide, carbonate etc. of alkali metal andalkaline earth metal, for example, sodium carbonate, potassiumcarbonate, lithium hydroxide, sodium hydroxide, potassium hydroxide,calcium hydroxide etc.; and, as organic base, tertiary amines,dialkylaminoanilines, and pyridines, for example, triethylamine,pyridine, 4-dimethylaminopyridine (DMAP), 1,4-diazabicyclo[2,2,2]octane(DABCO) and 1,8-diazabicyclo[5,4,0]undec-7-ene (DBU) etc.

The process (a) can be also conducted by adding a phase transfercatalyst. As the phase transfer catalyst usable in that case there canbe mentioned, for example, crown ethers, for example,dibenzo-18-crown-6,18-crown-6,15-crown-5 etc.

The process (a) can be conducted in a substantially wide range oftemperature. However, the temperatures in a range of generally about −10to about 80° C., preferably about 5 to about 40° C. are adequate.Although said reaction is conducted desirably under normal pressure, itcan be conducted optionally under elevated pressure or under reducedpressure.

In conducting process (a), the aimed compounds of the formula (I) can beobtained, for example, by reacting 1 to 4 moles of triethylamine to 1mole of a compound of the formula (II) in a diluent, for example,acetonitrile, in the presence of 0.01 to 0.5 moles of acetonecyanohydrin.

In conducting the preparation process (a), the aimed compounds of theformula (I) can be obtained by conducting a one-pot reaction startingfrom the compounds of formula (VIII) continuously without isolating thecompounds of the formula (VI) and the compounds of the formula (II).

The reaction of the process (b) can be conducted in an appropriatediluent. As the diluent used in that case there can be mentioned, forexample, aliphatic, alicyclic and aromatic hydrocarbons (may beoptionally chlorinated), for example, pentane, hexane, cyclohexane,petroleum ether, ligroine, benzene, toluene, xylene, dichloromethane,chloroform, carbon tetrachloride, 1,2-dichloroethane, chlorobenzeneetc.; ethers, for example, ethyl ether, methyl ethyl ether, isopropylether, butyl ether, dioxane, dimethoxyethane (DME), tetrahydrofuran(THF), diethylene glycol dimethyl ether (DGM) etc.; ketones, forexample, acetone, methyl ethyl ketone (MEK), methyl isopropyl ketone,methyl isobutyl ketone (MIBK) etc.; nitriles, for example, acetonitrile,propionitrile etc.; esters, for example, ethyl, acetate, amyl acetateetc.; acid amides, for example, dimethylformamide (DMF),dimethylacetamide (DMA), N-methylpyrrolidone,1,3-dimethyl-2-imidazolidinone, hexamethyl phosphoric triamide (HMPA)etc.

The reaction of the process (b) can be conducted in a substantially widerange of temperature. However, the temperatures in a range of generallyabout −20 to about 100° C., preferably about 0 to about 50° C. areadequate. Although said reaction is conducted desirably under normalpressure, it can be conducted optionally under elevated pressure orunder reduced pressure.

In conducting the preparation process (b), the aimed compounds of theformula (I) can be obtained, for example, by reacting 1 to 5 moles ofoxalyl dichloride to 1 mole of a compound of the formula (Ib) in adiluent, for example, dichloromethane.

The reaction of the process (c) can be conducted in an appropriatediluent. As the diluent used in that case there can be mentioned, forexample, aliphatic, alicyclic and aromatic hydrocarbons (may beoptionally chlorinated), for example, pentane, hexane, cyclohexane,petroleum ether, ligroine, benzene, toluene, xylene, dichloromethane,chloroform, carbon tetrachloride, 1,2-dichloroethane, chlorobenzene,dichlorobenzene etc.; ethers, for example, ethyl ether, methyl ethylether, isopropyl ether, butyl ether, dioxane, dimethoxyethane (DME),tetrahydrofuran (THF), diethylene glycol dimethyl ether (DGM) etc.;ketones, for example, acetone, methyl ethyl ketone (MEK), methylisopropyl ketone, methyl isobutyl ketone (MIBK) etc.; nitriles, forexample, acetonitrile, propionitrile, acrylonitrile etc.; esters, forexample, ethyl acetate, amyl acetate etc.; acid amides, for example,dimethylformamide (DMF), dimethylacetamide (DMA), N-methylpyrrolidoneetc.; sulfones and sulfoxides, for example, dimethyl sulfoxide (DMSO),sulfolane etc.; bases, for example, pyridine etc.

The process (c) can be conducted in the presence of an acid binder. Asthe usable acid binder there can be mentioned, as inorganic base,hydrides,carbonates etc. of alkali metal, for example, sodium hydride,lithium hydride, sodium carbonate, potassium carbonate etc.; and asorganic base, tertiary amines, dialkylaminoanilines, and pyridines, forexample, triethylamine, 1,1,4,4tetramethyl ethylenediamine (TMEDA),pyridine, 4-dimethylaminopyridine (DMAP),1,4-diazabicyclo[2,2,2]-octane(DABCO), 1,8diazabicyclo[5,4,0]undec-7-ene (DBU) etc.

The reaction of the process (c) can be conducted in a substantially widerange of temperature. However, the temperatures in a range of generallyabout −20 to about 140° C., preferably about 0 to about 100° C. areadequate. Although said reaction is conducted desirably under normalpressure, it can be conducted optionally under elevated pressure orunder reduced pressure.

In conducting the process (c), the aimed compounds of the formula (I)can be obtained, for example, by reacting 1 to 5 moles of a compound ofthe formula (III) to 1 mole of a compound of the formula (Ic) in adiluent, for example, tetrahydrofuran, in the presence of 1 to 5 molesof triethylamine.

The reaction of the process (d) can be conducted in an appropriatediluent. As the diluent used in that case there can be mentioned, forexample, aliphatic, alicyclic and aromatic hydrocarbons (may beoptionally chlorinated), for example, pentane, hexane, cyclohexane,petroleum ether, ligroine, benzene, toluene, xylene, dichloromethane,chloroform, carbon tetrachloride, 1,2-dichloroethane, chlorobenzene,dichlorobenzene etc.; ethers, for example, ethyl ether, methyl ethylether, isopropyl ether, butyl ether, dioxane, dimethoxyethane (DME),tetrahydrofuran (THF), diethylene glycol dimethyl ether (DGM) etc.;ketones, for example, acetone, methyl ethyl ketone (MEK), methylisopropyl ketone, methyl isobutyl ketone (MIBK) etc.; esters, forexample, ethyl acetate, amyl acetate etc.; acid amides, for example,dimethylformamide (DMF), dimethylacetamide (DMA), N-methylpyrrolidone,1,3-dimethyl-2-imidazolidinone, hexamethyl phosphoric triamide (HMPA)etc.; sulfones and sulfoxides, for example, dimethyl sulfoxide (DMSO),sulfolane etc.; bases, for example, pyridine etc.

The process (d) can be conducted in the presence of an acid binder. Asthe usable acid binder there can be mentioned, as inorganic base,hydrides, carbonates etc. of alkali metal and alkaline earth metal, forexample, sodium hydride, lithium hydride, sodium carbonate, potassiumcarbonate etc.; and as organic base, tertiary amines,dialkylaminoanilines, and pyridines, for example, triethylamine,1,1,4,4-tetramethyl ethylenediamine (TMEDA), N,N-dimethylaniline,N,N-diethylaniline, pyridine, 4-dimethylaminopyridine (DMAP),1,4-diazabicyclo[2,2,2]octane (DABCO),1,8-di-azabicyclo[5,4,0]undec-7-ene (DBU) etc.

The process (d) can be conducted in a substantially wide range oftemperature. However, the temperatures in a range of generally about −20to about 140° C., preferably about 0 to about 100° C. are adequate.Although said reaction is conducted desirably under normal pressure, itcan be conducted optionally under elevated pressure or under reducedpressure.

In conducting process (d), the aimed compounds of the formula (I) can beobtained, for example, by reacting 1-5 moles of a compound of theformula (IV) to 1 mole of a compound of the formula (Ib) in a diluent,for example, tetrahydrofuran, in the presence of triethylamine.

The reaction of the process (e) can be conducted in an appropriatediluent. As the diluent used in that case there can be mentioned, forexample, ethers, for example, dioxane, tetrahydrofuran (THF) etc.;alcohols, for example, tert-amyl alcohol, tert-butyl alcohol etc.

The process (e) can be conducted in the presence of a base. As the baseusable in that case there can be mentioned, as inorganic base, carbonateetc. of alkali metal, for example, sodium carbonate, potassium carbonateetc.; and as organic base, tertiary amines, for example, triethylamine,pyridine, 4-dimethylaminopyridine (DMAP) etc. The preparation process(e) can be conducted in a substantially wide range of temperature.However, the temperatures in a range of generally about 5 to about 200°C., preferably about 25 to about 130° C. are adequate. Although saidreaction is conducted desirably under normal pressure, it can beconducted optionally under elevated pressure or under reduced pressure.

In conducting the process (e), the aimed compounds of the formula (I)can be obtained, for example, by reacting 0.5 to 2 moles of potassiumcarbonate to 1 mole of a compound of the formula (IIe) in a diluent, forexample, dioxane.

The reaction of process (f) can be conducted in an appropriate diluent.As the diluent used in that case there can be mentioned, for example,aliphatic, alicyclic and aromatic hydrocarbons (may be optionallychlorinated), for example, toluene, dichloromethane, chloroform,1,2-dichloroethane etc.; ethers, for example, tetrahydrofuran (THF)etc.; nitrites, for example, acetonitrile etc.; alcohols, for example,methanol, ethanol, isopropanol etc.

The process (f) can be conducted in the presence of a base. As the baseusable in that case there can be mentioned, as inorganic base, acetate,carbonate, bicarbonate etc. of alkali metal and alkaline earth metal,for example, sodium acetate, sodium hydrogen carbonate, potassiumhydrogen carbonate, sodium carbonate, potassium carbonate etc.; and asorganic base, tertiary amines, dialkylaminoanilines and pyridines, forexample, triethylamine, pyridine, 4-dimethylaminopyridine (DMAP) etc.

The process (f) can be conducted in a substantially wide range oftemperature. However, the temperatures in a range of generally about −10to about 100° C., preferably about 0 to about 50° C. are adequate.Although said reaction is conducted desirably under normal pressure, itcan be conducted optionally under elevated pressure or under reducedpressure.

In conducting the process (f), the aimed compounds of the formula (I)can be obtained, for example, by reacting 1 to 1.5 moles ofhydroxylamine hydrochloride to 1 mole of a compound of the formula (V)in a diluent, for example, ethanol, in the presence of 1 to 1.5 moles ofsodium acetate.

In conducting the process (f), the aimed compounds of the formula (I)can be obtained by starting from the compounds of the formula (VI) toobtain the compounds of the formula (XII) by continuously reactingwithout isolating the compounds of the formula (XIV) and further bycontinuously reacting, starting from the compounds of the formula (XII)without isolating the compounds of the formula (V).

The reaction of the process (g) can be conducted in an appropriatediluent. As the diluent used in that case there can be mentioned, forexample, water; aliphatic, alicyclic and aromatic hydrocarbons (may beoptionally chlorinated), for example, benzene, toluene, xylene,dichloromethane, chloroform, carbon tetrachloride, 1,2-dichloroethaneetc.; ethers, for example, ethyl ether, dioxane, dimethoxyethane (DME),tetrahydrofuran (THF) etc.; nitriles, for example, acetonitrile etc.;alcohols, for example, methanol, ethanol, isopropanol etc.; esters, forexample, ethyl acetate etc.; acid amides, for example, dimethylformamide(DMF) etc.

The process (g) can be conducted in the presence of a base. As the baseusable in that case there can be mentioned, as inorganic base,hydroxide, carbonate etc. of alkali metal and alkaline earth metal, forexample, sodium carbonate, potassium carbonate, lithium hydroxide,sodium hydroxide, potassium hydroxide, calcium hydroxide etc.; and asorganic base, alcoholates, tertiary amines, dialkylaminoanilines andpyridines, for example, triethylamine, 1,1,4,4-tetramethylethylenediamine (TMEDA), 4-dimethylaminopyridine (DMAP) etc.

The process (g) can be conducted in a substantially wide range oftemperature. However, the temperatures in a range of generally about −10to about 100° C., preferably about 0 to about 50° C. are adequate.Although said reaction is conducted desirably under normal pressure, itcan be conducted optionally under elevated pressure or under reducedpressure.

In conducting the process (g), the aimed compounds of the formula (I)can be obtained, for example, by opening the ring of a compound of theformula (Ig) in a diluent, for example, dichloromethane, in the presenceof 1 to 3 moles of triethylamine to 1 mole of the compound of theformula (Ig).

The compounds of formula (I) show excellent herbicidal activitiesagainst various weeds and can be used as herbicides. In the presentspecification weeds mean, in a broader sense, all plants that grow inlocations where they are not desired. The compounds, according to thepresent invention, act as total or selective herbicide depending uponthe applied concentration. The active compounds, according to thepresent invention, can be used, for example, between the following weedsand cultures.

Genera of the dicotyledonous weeds: Sinapis, Lepidium, Galium,Stellaria, Chenopodium, Urtica, Senecio, Amaranthus, Portulaca,Xanthium, Ipomoea, Polygonum, Ambrosia, Cirsium, Sonchus, Solanum,Rorippa, Lamium, Veronica, Datura, Viola, Galeopsis, Papaver, Centaurea,Galinsoga, Rotala, Lindernia etc.

Genera of the dicotyledonous cultures: Gossypium, Glycine, Beta, Daucus,Phaseolus, Pisum, Solanum, Linum, Ipomoea, Vicia, Nicotiana,Lycopersicon, Arachis, Brassica, Lactuca, Cucumis, Cucurbita etc.

Genera of the monocotyledonous weeds: Echinochloa, Setaria, Panicum,Digitaria, Phleum, Poa, Festuca, Eleusine, Lolium, Bromus, Avena,Cyperus, Sorghum, Agropyron, Monochoria, Fimbristylis, Sagittaria,Eleocharis, Scirpus, Paspalum, Ischaemum, Agrostis, Alopecurus, Cynodonetc.

Genera of the monocotyledonous cultures: Oryza, Zea, Triticum, Hordeum,Avena, Secale, Sorghum, Panicum, Saccharum, Ananas, Asparagus, Alliumetc.

The active compounds of the formula (I), according to the presentinvention and mixed herbicidal compositions can be used particularlyagainst paddy field weeds. As paddy field weeds that can be controlledby using the compounds, according to the present invention, and mixedherbicidal compositions there can be specifically mentioned, forexample, Rotala indica Koehne, Lindernia Procumbens Philcox, Ludwigiaprostrata Roxburgh, Potamogeton distinctus A. Benn, Elatine triandraSchk, Oenanthe javanica, Echinochloa oryzicola Vasing, Monochoriavaginalis Presl, Eleocharis acicularis L., Eleocharis Kuroguwai Ohwi,Cyperus difformis L., Cyperus serotinus Rottboel, Sagittaria pygmaeaMiq, Alisma canaliculatum A. Br. Et Bouche, Scirpus juncoides Roxburghetc. Moreover, the compounds of the formula (I) and mixed herbicidalcompositions can be used against weeds that show resistance againstsulfonylurea type herbicides. As said resistant weeds there can bespecifically mentioned, for example, Rotala indica Koehne, LinderniaProcumbens Philcox, Lindernia dubia L. PENNEL, Lindernia var. dubiaPennell, Lindernia angustifolia Wettstein, Elatine triandra Schk,Monochoria korsakowii REGEL & MACK, Monochoria vaginalis Presl, Scirpusjuncoides Roxburgh etc. The use of the active compounds of the formula(I) of the present invention and mixed herbicidal compositions, however,is not restricted to the use against these weeds but can be appliedagainst other paddy field weeds and other weeds than the sulfonylureatype herbicide-resistant weeds in a similar manner.

The use of the compounds, according to the present invention, is notrestricted to the above-mentioned plants, but can be applied againstother plants in a similar manner. The active compounds, according to thepresent invention, can, depending upon the applied concentration,non-selectively control weeds and can be used, for example, onindustrial terrain such as factories, rail tracks, paths, places with orwithout tree plantings. Moreover, the active compounds of the presentinvention can be used for controlling weeds in perennial cultures andcan be applied, for example, in afforestations, decorative treeplantings, orchards, vineyards, citrus groves, nut orchards, bananaplantations, coffee plantations, tea plantations, rubber plantations,oil palm plantations, cocoa plantations, soft fruit plantings, hopfields etc. Further, they can be applied for the selective weed controlin annual cultures.

The active compounds, according to the present invention, and mixedherbicidal compositions can be made into customary formulation forms. Assuch formulation forms there can be mentioned, for example, solutions,wettable powders, emulsions, suspensions, powders, water dispersiblegranules, tablets, granules, suspo-emulsion concentrates, microcapsulesin polymer substance, jumbo formulations etc.

These formulations can be prepared according to per se known methods,for example, by mixing the active compounds with extenders, namelyliquid or solid diluents or carriers, and optionally with surface-activeagents, namely emulsifiers and/or dispersants and/or foam-formingagents.

As liquid diluents or carriers there can be mentioned, for example,aromatic hydrocarbons (for example, xylene, toluene, alkylnaphthaleneetc.), chlorinated aromatic or chlorinated aliphatic hydrocarbons (forexample, chlorobenzenes, ethylene chlorides, methylene chloride etc.),aliphatic hydrocarbons [for example, cyclohexane etc. or paraffins (forexample, mineral oil fractions etc.)], alcohols (for example, butanol,glycols etc.) and their ethers, esters etc., ketones (for example,acetone, methyl ethyl ketone, methyl isobutyl ketone, cyclohexanoneetc.), strongly polar solvents (for example, dimethylformamide, dimethylsulfoxide etc.), water etc. When water is used as extender, for example,organic solvents can be used as auxiliary solvents.

As solid diluents or carriers there can be mentioned, for example,ground natural minerals (for example, kaolin, clay, talc, chalk, quartz,attapulgite, montmorillonite, diatomaceous earth etc.), ground syntheticminerals (for example, highly dispersed silicic acid, alumina, silicatesetc.) etc. As solid carriers for granules there can be mentioned crushedand fractionated rocks (for example, calcite, marble, pumice, sepiolite,dolomite etc.) synthetic granules of inorganic and organic meals,particles of organic materials (for example, saw dust, coconut shells,maize cobs, tobacco stalks etc.) etc.

As emulsifiers and/or foam-forming agents there can be mentioned, forexample, nonionic and anionic emulsifiers [for example, polyoxyethylenefatty acid esters, polyoxyethylene fatty acid alcohol ethers (forexample, alkylaryl polyglycol ethers, alkylsulfonates, alkylsulfates,arylsulfonates etc.)], albumin hydrolysis products etc.

Dispersants include, for example, lignin sulfite waste liquor, methylcellulose etc.

Tackifiers can also be used in formulations (powders, granules,emulsifiable concentrates). As said tackifiers there can be mentioned,for example, carboxymethyl cellulose, natural and synthetic polymers(for example, gum Arabic, polyvinyl alcohol, polyvinyl acetate etc.).

Colorants can also be used. As said colorants there can be mentionedinorganic pigments (for example, iron oxide, titanium oxide, PrussianBlue etc,), organic dyestuffs such as alizarin dyestuffs, azo dyestuffsor metal phthalocyanine dyestuffs, and further traces nutrients such assalts of metals such as iron, manganese, boron, copper, cobalt,molybdenum, zinc etc.

Said formulations can contain the active compounds of the formula (I) inthe range of generally 0.1 to 95% by weight, preferably 0.5 to 90% byweight.

The active compounds of the formula (I), according to the presentinvention, can be used for weed control as themselves or in theirformulation forms. And the mixed herbicidal compositions with knownherbicides can be previously prepared in the final formulation forms orcan be prepared by tank mixing when they are used. As the herbicidesthat can be used as mixed herbicidal compositions in combination withthe compounds of the formula (I) of the present invention there can bementioned, for example, the following herbicides represented by commonnames as typical examples:

-   -   acetamide type herbicides: for example, pretilachlor, butachlor,        thenylchlor, alachlor etc.;    -   amide type herbicides: for example, clomeprop, etobenzanid etc.;    -   benzofuran type herbicides: for example, benfuresate etc.;    -   indandione type herbicides: for example, indanofan etc.;    -   pyrazole type herbicides: for example, pyrazolate, benzofenap,        pyrazoxifen etc.;    -   oxazinone type herbicides: for example, oxaziclomefone etc.;    -   sulfonylurea type herbicides: for example, bensulfuron-methyl,        azimsulfuron, imazosulfuron, pyrazosulfuron-ethyl,        cyclosulfamuron, ethoxysulfuron, halosulfuronmethyl etc.;    -   thiocarbamate type herbicides: for example, thiobencarb,        molinate, pyributycarb etc.;    -   triazine type herbicides: for example, dimethametryn, simetryn        etc.;    -   triazole type herbicides: for example, cafenstrole etc.;    -   quinoline type herbicides: for example, quinclorac etc.;    -   isoxazole type herbicides: for example, isoxaflutole etc.;    -   dithiophosphate type herbicides: for example, anilofos etc.;    -   oxyacetamide type herbicides: for example, mefenacet, flufenacet        etc.;    -   tetrazolinone type herbicides: for example, fentrazamide etc.;    -   dicarboxyimide type herbicides: for example, pentoxazone etc.;    -   trione type herbicides: for example, sulcotrione, benzobicyclon        etc.;    -   phenoxypropionate type herbicides: for example, cyhalofop-butyl        etc.;    -   benzoic acid type herbicides: for example, pyrimenobac-methyl        etc.;    -   diphenyl ether type herbicides: for example, chlomethoxyfen,        oxyfluorfen etc.;    -   pyridine dicarbothioate type herbicides: for example, dithiopyr        etc.;    -   phenoxy type herbicides: for example, MCPA, MCPB etc.;    -   urea type herbicides: for example, dymron, cumyluron etc.;    -   naphthalenedione type herbicides: for example, quinoclamine        etc.;    -   isoxazolidinone type herbicides: for example, clomazone etc.

In addition to the above mentioned herbicides, the following herbicidesshown in common names, for example,

Acetochlor, Acifluorfen (-sodium), Aclonifen, Alloxydim (-sodium),Ametryne, Amicarbazone, Amidochlor, Amidosulfuron, Amitrole, Asulam,Atrazine, Azafenidin, Beflubutamid, Benazolin (-ethyl), Bentazon,Benzfendizone, Benzoylprop (-ethyl), Bialaphos, Bifenox, Bispyribac(-sodium), Bromacil, Bromobutide, Bromofenoxim, Bromoxynil, Butafenacil(-allyl), Butenachlor, Butralin, Butroxydim, Butylate, Carbetamide,Carfentrazone (-ethyl), Chloramben, Chloridazon, Chlorimuron (-ethyl),Chlornitrofen, Chlorsulfuron, Chlorthiamid, Chlortoluron, Cinidon(-ethyl), Cinmethylin, Cinosulfuron, Clefoxydim, Clethodim, Clodinafop(-propargyl), Clopyralid, Cloransulam (-methyl), Cyanazine, Cybutryne,Cycloate, Cycloxydim, 2,4-D, 2,4-DB, Desmedipham, Diallate, Dicamba,Dichlobenil, Dichlorprop (—P), Diclofop (-methyl), Diclosulam, Diethatyl(-ethyl), Difenopenten (-ethyl), Difenzoquat, Diflufenican,Diflufenzopyr, Dikegulac (-sodium), Dimefuron, Dimepiperate,Dimethachlor, Dimethenamid (—P), Dimexyflam, Dinitramine, Diphenamid,Diquat (-dibromide), Diuron, Epropodan, EPTC, Esprocarb, Ethalfluralin,Ethametsulfuron (-methyl), Ethiozin, Ethofumesate, Ethoxyfen, Fenoxaprop(—P-ethyl), Flamprop (-M-isopropyl, -M-methyl), Flazasulfuron,Florasulam, Fluazifop (—P-butyl), Fluazolate, Flucarbazone (-sodium),Fluchloralin, Flumetsulam, Flumiclorac (-pentyl), Flumioxazin,Flumipropyn, Fluometuron, Fluorochloridone, Fluoroglycofen (-ethyl),Flupoxam, Flupropacil, Flurpyrsulfuron (-methyl, -sodium), Flurenol(-butyl), Fluridone, Fluroxypyr (-butoxypropyl, -meptyl), Flurprimidol,Flurtamone, Fluthiacet (-methyl), Fomesafen, Foramsulfuron, Glufosinate(-ammonium), Glyphosate (-ammonium, -isopropylammonium), Halosafen,Haloxyfop (-ethoxyethyl, —P-methyl), Hexazinone, Imazamethabenz(-methyl), Imazamethapyr, Imazamox, Imazapic, Imazapyr, Imazaquin,Imazethapyr, lodosulfuron (-methyl, -sodium), loxynil, Isopropalin,Isoproturon, Isouron, Isoxaben, Isoxachlortole, Isoxadifen (-ethyl),Isoxapyrifop, Ketospiradox, Lactofen, Lenacil, Linuron, Mecoprop (—P),Mesotrione, Metamitron, Metazachlor, Methabenzthiazuron, Methyldymron,Metobenzuron, Metobromuron, (S—) Metolachlor, Metosulam, Metoxuron,Metribuzin, Metsulfuron (-methyl), Monolinuron, Naproanilide,Napropamide, Neburon, Nicosulfuron, Norflurazon, Orbencarb, Oryzalin,Oxadiargyl, Oxadiazon, Oxasulfuron, Paraquat, Pelargonsaiure,Pendimethalin, Pendralin, Pethoxamid, Phenmedipham, Picolinafen,Piperophos, Primisulfuron (-methyl), Profluazol, Profoxydim, Prometryn,Propachlor, Propanil, Propaquizafop, Propisochlor, Propoxycarbazone(-sodium), Propyzamide, Prosulfocarb, Prosulfuron, Pyraflufen (-ethyl),Pyrazogyl, Pyribenzoxim, Pyridafol, Pyridate, Pyridatol, Pyriftalid,Pyrithiobac (-sodium), Quinmerac, Quizalofop (—P-ethyl, —P-tefuryl),Rimsulfuron, Sethoxydim, Simazine, Sulfentrazone, Sulfometuron(-methyl), Sulfosate, Sulfosulfuron, Tebutam, Tebuthiuron, Tepraloxydim,Terbuthylazine, Terbutryn, Thiazopyr, Thidiazimin, Thifensulfuron(-methyl), Tiocarbazil, Tralkoxydim, Triallate, Triasulfuron, Tribenuron(-methyl), Triclopyr, Tridiphane, Trifloxysulfuron, Trifluralin,Triflusulfuron (-methyl), Tritosulfuron.

Further, when the active compounds of the formula (I), according to thepresent invention, are mixed with safeners, phytotoxicity is reduced bythe mixing and a broader weed controlling spectrum is provided and theapplication as a selective herbicide can be broadened.

As safeners there can be mentioned, for example, the following compoundsrepresented by common names or development codes:

AD-67, BAS-145138, benoxacor, cloquintocet-mexyl, cyometrinil, 2,4-D,DKA-24, dichlormid, dymron, fenclorim, fenchlorazole-ethyl, flurazole,fluxofenim, flurazole, isoxadifen-ethyl, mefenpyr-diethyl, MG-191,naphthalic anhydride, oxabetrinil, PPG-1292, R-29148 etc.

The above-mentioned safeners and active compounds are also described in“The Pesticide Manual” published in 2000 by British Crop ProtectCouncil.

Moreover, it is possible to further mix the above-mentioned safeners toa mixed herbicide composition consisting of a compound of the formula(I) of the present invention and an above-mentioned herbicide. By themixing phytotoxicity is reduced and a broader weed controlling spectrumis provided and the application as a selective herbicide can bebroadened.

Surprisingly, some of the mixed herbicide compositions consisting of acompound of the present invention and a known herbicide and/or a safenercan show synergistic effects.

In case of using the active compounds of the formula (I), according tothe present invention, they can be directly used as such or used informulation forms such as ready-to-use solutions, emulsifiableconcentrates, tablets, suspensions, powders, pastes or granules, or usedin use forms prepared by further dilution. The active compounds,according to the present invention, can be applied by means of, forexample, watering, spraying, atomizing, granule application etc.

The active compounds of the formula (I), according to the presentinvention, can be used at wither stages before and after germination ofplants. They can be also mixed into the soil before sowing.

The application amount of the active compounds, according to the presentinvention, can be varied in a substantial range. It is fundamentallydifferent depending upon the properties of effects to be desired. Incase of using as herbicide, there can be mentioned application amountsin the range of, for example, about 0.01 to about 4 kg, preferably about0.05 to about 3 kg as active compound per hectare.

Then the preparation and application of the compounds, according to thepresent invention, will be described more specifically by the followingexamples. The present invention, however, should not be restricted onlyto them in any way.

SYNTHESIS EXAMPLE 1

3-Oxo-1-cyclohexenyl 2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoate(0.48 g) was dissolved in acetonitrile (15 ml), to which triethylamine(0.25 g) and acetone cyanohydrin (5 mg) were added and stirred at roomtemperature for 5 hours. After the solvent was distilled off, it wasacidified by addition of diluted hydrochloric acid and extracted withdichloromethane (150 ml). The organic layer was washed with saturatedaqueous solution of common salt and dried with anhydrous magnesiumsulfate. Dichloromethane was distilled off to obtain the objective2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}cyclohexane-1,3-dione(0.41 g).

n^(D) ₂₀: 1.5960

SYNTHESIS EXAMPLE 2

To a solution of2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}cyclohexane-1,3-dione(0.61 g) in dichloromethane (100 ml), oxalyl chloride (0.39 g) and 2drops of N,N-dimethylformamide were added drop by drop under icecooling. After that, the reaction solution was gradually warmed andrefluxed for 3 hours. After the reaction, the solvent was distilled offand the obtained residue was purified by silica gel columnchromatography (eluent:ethyl acetate:hexane=7:3) to obtain the objective3-chloro-2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}-2-cyclohexen-1-one(0.45 g).

Mp: 122-124° C.

SYNTHESIS EXAMPLE 3

In tetrahydrofuran (7 ml)3-chloro-2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]-benzoyl}-2-cyclohexen-1-one(0.33 g) and thiophenol (0.10 g) were dissolved, to which triethylamine(0.10 g) in tetrahydrofuran (3 ml) was added drop at 5° C. by drop andstirred at room temperature for 4 hours. After the reaction, cold waterwas added thereto and the mixture was extracted with ethyl acetate (50ml) and dried with anhydrous magnesium sulfate. After ethyl acetate wasdistilled off, the obtained residue was purified by silica gel columnchromatography (eluent:ethyl acetate:hexane=2:1) to obtain the objective2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]-benzoyl}-3-phenylthio-2-cyclohexen-1-one(0.33 g).

Mp: 64-70° C.

SYNTHESIS EXAMPLE 4

5-{2,4-Dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyloxy}-1-ethylpyrazole(0.58 g) was dissolved in acetonitrile (10 ml), to which triethylamine(0.30 g) and acetone cyanohydrin (4 mg) were added and stirred at roomtemperature for 5 hours. After the solvent was distilled off, it wasacidified by addition of diluted hydrochloric acid and extracted withethyl acetate (150 ml). The organic layer was washed with saturatedaqueous solution of common salt and dried with anhydrous magnesiumsulfate. Ethyl acetate was distilled off to obtain the objective2-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyl}cyclohexane-1,3-dione(0.41 g).

Mp: 46-54° C.

The compounds obtained by operating in a similar manner as thepreparation processes of the compounds of the formula (I) of the presentinvention exemplified in the above-mentioned Synthesis Examples 1-4, areshown, together with the compounds synthesized in Synthesis Examples1-4, in the following Table 1 and Table 2.

Examples of the compounds of the formula (I) when they are representedby the formula

are shown in Table 1, and, when they are represented by the formula

they are shown in Table 2.

The following abbreviations are used in table 1 and 2:

Further, Me represents methyl, Et represents ethyl, n-Pr representsn-propyl, i-Pr reprents isopropyl, n-Bu represents n-butyl, n-Penrepresents n-pentyl, cyclo-Pro represents cyclopropyl, cyclo-Burepresents cyclobutyl, cyclo-Pen represents cyclopentyl, cyclo-Hexrepresents cyclohexyl, n-Hex represents n-hexyl, OMe represents methoxy,OEt represents ethoxy, SMe represents methylthio, SEt representsethylthio, S-n-Pr represents n-propylthio, SO₂Me representsmethylsulfonyl, SO₂Et represents ethylsulfonyl, SO₂Pr-n representsn-propylsulfonyl, OSO₂Me represents methylsulfonyloxy, OSO₂Et representsethylsulfonyloxy, Ph represents phenyl, 2-Cl-Ph represents2-chlorophenyl, 3-Cl-Ph represents 3-chlorophenyl, 2-Me-Ph represents2-methylphenyl, 4-Me-Ph represents 4-methylphenyl, 3-Et-Ph represents3-ethylphenyl, 4-n-Pr-Ph represents 4-(n-propyl)phenyl, 3-CF₃—Phrepresents 3-trifluoromethylphenyl, 3-CH₂CF₃—Ph represents3-(2,2,2-trifluoroethyl)phenyl and 3-NO₂—Ph represents 3-nitrophenyl.TABLE 1 Compd. Mp (° C.) No. R^(1a) R^(1b) (R^(1c)) (O)_(n)—A R² Q orn_(D) ²⁰ 1. H Cl OCH₂CH₂ H Q1a 2. H Cl OCH₂CH₂ H Q2a 3. F Cl CH₂ H Q1a4. F Cl OCH₂CH₂ H Q1a 5. F Cl CH₂ Me Q1a 6. Cl F CH₂ H Q1a 7. Cl F CH₂Me Q1a 8. Cl F OCH₂CH₂ H Q1a 9. Cl F OCH₂CH₂ H Q1b 10. Cl F OCH₂CH₂ HQ1c 11. Cl F OCH₂CH₂ H Q1d 12. Cl F OCH₂CH₂ H Q1e 13. Cl F OCH₂CH₂ H Q2a14. Cl F OCH₂CH₂ H Q2b 15. Cl F OCH₂CH₂ H Q3a 16. Cl F OCH₂CH₂ H Q3c 17.Cl F OCH₂CH₂ H Q4a 18. Cl F OCH₂CH₂ H Q5a 19. Cl F OCH₂CH₂ H Q6a 20. ClF OCH₂CH₂ H Q8a 21. Cl F OCH₂CH₂ H Q8d 22. Cl F OCH₂CH₂ H Q9a 23. Cl FOCH₂CH₂ H Q12 24. Cl F OCH₂CH₂ H Q13 25. Cl F OCH₂CH₂ Me Q1a 26. Cl FOCH₂CH₂ Me Q2a 27. Cl F OCH₂CH₂ Me Q2b 28. Cl F OCH₂CH₂ Me Q3a 29. Cl FOCH₂CH₂ Me Q6a 30. Cl F OCH₂CH₂ Me Q8d 31. Cl F OCH₂OH(Me) H Q1a 32. ClF OCH₂CH₂CH₂ H Q1a 33. Cl Cl CH₂ H Q1a 61-64 34. Cl Cl CH₂ H Q1b 35. ClCl CH₂ H Q1c 36. Cl Cl CH₂ H Q1d 37. Cl Cl CH₂ H Q1e 38. Cl Cl CH₂ H Q2a39. Cl Cl CH₂ H Q2b 40. Cl Cl CH₂ H Q3a 179-180 41. Cl Cl CH₂ H Q3b 42.Cl Cl CH₂ H Q3c 43. Cl Cl CH₂ H Q3d 44. Cl Cl CH₂ H Q3e 45. Cl Cl CH₂ HQ3f 46. Cl Cl CH₂ H Q3g 47. Cl Cl CH₂ H Q3h 48. Cl Cl CH₂ H Q31 49. ClCl CH₂ H Q3j 50. Cl Cl CH₂ H Q3k 51. Cl Cl CH₂ H Q3l 52. Cl Cl CH₂ H Q3m53. Cl Cl CH₂ H Q3n 54. Cl Cl CH₂ H Q3o 55. Cl Cl CH₂ H Q3p 56. Cl ClCH₂ H Q3q 57. Cl Cl CH₂ H Q3r 58. Cl Cl CH₂ H Q3s 59. Cl Cl CH₂ H Q3t60. Cl Cl CH₂ H Q3u 61. Cl Cl CH₂ H Q3v 62. Cl Cl CH₂ H Q3w 63. Cl ClCH₂ H Q3x 64. Cl Cl CH₂ H Q3y 65. Cl Cl CH₂ H Q3z 66. Cl Cl CH₂ H Q3za67. Cl Cl CH₂ H Q3zb 68. Cl Cl CH₂ H Q3zc 69. Cl Cl CH₂ H Q3zd 70. Cl ClCH₂ H Q4a 71. Cl Cl CH₂ H Q4b 72. Cl Cl CH₂ H Q4c 73. Cl Cl CH₂ H Q4d74. Cl Cl CH₂ H Q5a 75. Cl Cl CH₂ H Q5b 76. Cl Cl CH₂ H Q5c 77. Cl ClCH₂ H Q6a 78. Cl Cl CH₂ H Q6b 79. Cl Cl CH₂ H Q7 80. Cl Cl CH₂ H Q8a 81.Cl Cl CH₂ H Q8b 82. Cl Cl CH₂ H Q8c 83. Cl Cl CH₂ H Q8d 84. Cl Cl CH₂ HQ9a 85. Cl Cl CH₂ H Q9b 86. Cl Cl CH₂ H Q9c 87. Cl Cl CH₂ H Q9d 88. ClCl CH₂ H Q10a 89. Cl Cl CH₂ H Q11a 90. Cl Cl CH₂ H Q12 91. GI Cl CH₂ HQ13 92. Cl Cl CH₂ H Q14 93. Cl Cl CH₂ H Q15 94. Cl Cl CH₂ Me Q1a 95. ClCl CH₂ Me Q1b 96. Cl Cl CH₂ Me Q1c 97. Cl Cl CH₂ Me Q1d 98. Cl Cl CH₂ MeQ1e 99. Cl Cl CH₂ Me Q2a 100. Cl Cl CH₂ Me Q2b 101. Cl Cl CH₂ Me Q3a102. Cl Cl CH₂ Me Q3b 103. Cl Cl CH₂ Me Q3c 104. Cl Cl CH₂ Me Q3d 105.Cl Cl CH₂ Me Q3e 106. Cl Cl CH₂ Me Q3f 107. Cl Cl CH₂ Me Q3g 108. Cl ClCH₂ Me Q3h 109. Cl Cl CH₂ Me Q3i 110. Cl Cl CH₂ Me Q3j 111. Cl Cl CH₂ MeQ3k 112. Cl Cl CH₂ Me Q31 113. Cl Cl CH₂ Me Q3m 114. Cl Cl CH₂ Me Q3n115. Cl Cl CH₂ Me Q3o 116. Cl GI CH₂ Me Q3p 117. Cl Cl CH₂ Me Q3q 118.Cl Cl CH₂ Me Q3r 119. Cl Cl CH₂ Me Q3s 120. Cl Cl CH₂ Me Q3t 121. Cl ClCH₂ Me Q3u 122. Cl Cl CH₂ Me Q3v 123. Cl Cl CH₂ Me Q3w 124. Cl Cl CH₂ MeQ3x 125. Cl Cl CH₂ Me Q3y 126. Cl Cl CH₂ Me Q3z 127. Cl Cl CH₂ Me Q3za128. Cl Cl CH₂ Me Q3zb 129. Cl Cl CH₂ Me Q3zc 130. Cl Cl CH₂ Me Q3zd131. Cl Cl CH₂ Me Q4a 132. Cl Cl CH₂ Me Q4b 133. Cl Cl CH₂ Me Q4c 134.Cl Cl CH₂ Me Q4d 135. Cl Cl CH₂ Me Q5a 136. Cl Cl CH₂ Me Q6a 137. Cl ClCH₂ Me Q6b 138. Cl Cl CH₂ Me Q7 139. Cl Cl CH₂ Me Q8a 140. Cl Cl CH₂ MeQ8b 141. Cl Cl CH₂ Me Q8c 142. Cl Cl CH₂ Me Q8d 143. Cl Cl CH₂ Me Q9a144. Cl Cl CH₂ Me Q9b 145. Cl Cl CH₂ Me Q9c 146. Cl Cl CH₂ Me Q9d 147.Cl Cl CH₂ Me Q10a 148. Cl Cl CH₂ Me Q11a 149. Cl Cl CH₂ Me Q12 150. ClCl CH₂ Me Q13 151. Cl Cl CH₂ Me Q14 152. Cl Cl CH₂ Me Q15 153. Cl Cl CH₂Et Q1a 154. Cl Cl CH₂ Et Q1b 155. Cl Cl CH₂ Et Q1c 156. Cl Cl CH₂ Et Q1d157. Cl Cl CH₂ Et Q1e 158. Cl Cl CH₂ Et Q2a 159. Cl Cl CH₂ Et Q2b 160.Cl Cl CH₂ Et Q3a 161. Cl Cl CH₂ Et Q3c 162. Cl Cl CH₂ Et Q4a 163. Cl ClCH₂ Et Q5a 164. Cl Cl CH₂ Et Q6a 165. Cl Cl CH₂ Et Q8a 166. Cl Cl CH₂ EtQ8d 167. Cl Cl CH₂ Et Q9a 168. Cl Cl CH₂ Et Q12 169. Cl Cl CH₂ Et Q13170. Cl Cl CH₂ n-Pr Q1a 171. Cl Cl CH₂ n-Pr Q3a 172. Cl Cl CH₂ n-Pr Q6a173. Cl Cl CH₂ SMe Q1a 59-63 174. Cl Cl CH₂ SMe Q1b 175. Cl Cl CH₂ SMeQ1c 176. Cl Cl CH₂ SMe Q1d 177. Cl Cl CH₂ SMe Q1e 178. Cl Cl CH₂ SMe Q2a179. Cl Cl CH₂ SMe Q2b 180. Cl Cl CH₂ SMe Q3a 181. Cl Cl CH₂ SMe Q3c182. Cl Cl CH₂ SMe Q4a 183. Cl Cl CH₂ SMe Q5a 184. Cl Cl CH₂ SMe Q6a185. Cl Cl CH₂ SMe Q8a 186. Cl Cl CH₂ SMe Q8d 187. Cl Cl CH₂ SMe Q9a188. Cl Cl CH₂ SMe Q12 189. Cl Cl CH₂ SMe Q13 190. Cl Cl CH₂CH₂ H Q1a191. Cl Cl CH₂CH₂ H Q1b 192. Cl Cl CH₂CH₂ H Q1c 193. Cl Cl CH₂CH₂ H Q1d194. Cl Cl CH₂CH₂ H Q1e 195. Cl Cl CH₂CH₂ H Q2a 196. Cl Cl CH₂CH₂ H Q2b197. Cl Cl CH₂CH₂ H Q3a 198. Cl Cl CH₂CH₂ H Q3c 199. Cl Cl CH₂CH₂ H Q4a200. Cl Cl CH₂CH₂ H Q5a 201. Cl Cl CH₂CH₂ H Q6a 202. Cl Cl CH₂CH₂ H Q8a203. Cl Cl CH₂CH₂ H Q8d 204. Cl Cl CH₂CH₂ H Q9a 205. Cl Cl CH₂CH₂ H Q12206. Cl Cl CH₂CH₂ H Q13 207. Cl Cl CH₂CH₂ Me Q1a 208. Cl Cl CH₂CH₂ MeQ2a 209. Cl Cl CH₂CH₂ Me Q2b 210. Cl Cl CH₂CH₂ Me Q3a 211. Cl Cl CH₂CH₂Me Q6a 212. Cl Cl OCH₂CH₂ H Q1a 1.5960 213. Cl Cl OCH₂CH₂ H Q1b 1.5710214. Cl Cl OCH₂CH₂ H Q1c 215. Cl Cl OCH₂CH₂ H Q1d 1.5758 216. Cl ClOCH₂CH₂ H Q1e 217. Cl Cl OCH₂CH₂ H Q2a 56-60 218. Cl Cl OCH₂CH₂ H Q2b1.5830 219. Cl Cl OCH₂CH₂ H Q3a 64-70 220. Cl Cl OCH₂CH₂ H Q3b 221. ClCl OCH₂CH₂ H Q3c 222. Cl Cl OCH₂CH₂ H Q3d 223. Cl Cl OCH₂CH₂ H Q3e 224.Cl Cl OCH₂CH₂ H Q3f 225. Cl Cl OCH₂CH₂ H Q3g 226. Cl Cl OCH₂CH₂ H Q3h227. Cl Cl OCH₂CH₂ H Q3i 228. Cl Cl OCH₂CH₂ H Q3j 229. Cl Cl OCH₂CH₂ HQ3k 230. Cl Cl OCH₂CH₂ H Q31 231. Cl Cl OCH₂CH₂ H Q3m 232. Cl Cl OCH₂CH₂H Q3n 233. Cl Cl OCH₂CH₂ H Q3o 234. Cl Cl OCH₂CH₂ H Q3p 235. Cl ClOCH₂CH₂ H Q3q 236. Cl Cl OCH₂CH₂ H Q3r 237. Cl Cl OCH₂CH₂ H Q3s 238. ClCl OCH₂CH₂ H Q3t 239. Cl Cl OCH₂CH₂ H Q3u 240. Cl Cl OCH₂CH₂ H Q3v 241.Cl Cl OCH₂CH₂ H Q3w 242. Cl Cl OCH₂CH₂ H Q3x 243. Cl Cl OCH₂CH₂ H Q3y244. Cl Cl OCH₂CH₂ H Q3z 245. Cl Cl OCH₂CH₂ H Q3za 246. Cl Cl OCH₂CH₂ HQ3zb 247. Cl Cl OCH₂CH₂ H Q3zc 248. Cl Cl OCH₂CH₂ H Q3zd 249. Cl ClOCH₂CH₂ H Q4a 250. Cl Cl OCH₂CH₂ H Q4b 251. Cl Cl OCH₂CH₂ H Q4c 252. ClCl OCH₂CH₂ H Q4d 253. Cl Cl OCH₂CH₂ H Q5a 254. Cl Cl OCH₂CH₂ H Q5b 255.Cl Cl OCH₂CH₂ H Q5c 256. Cl Cl OCH₂CH₂ H Q5d 257. Cl Cl OCH₂CH₂ H Q5e258. Cl Cl OCH₂CH₂ H Q6a 122-124 259. Cl Cl OCH₂CH₂ H Q6b 260. Cl ClOCH₂CH₂ H Q7 261. Cl Cl OCH₂CH₂ H Q8a 262. Cl Cl OCH₂CH₂ H Q8b 263. ClCl OCH₂CH₂ H Q8c 264. Cl Cl OCH₂CH₂ H Q8d 265. Cl Cl OCH₂CH₂ H Q9a 266.Cl Cl OCH₂CH₂ H Q9b 267. Cl Cl OCH₂CH₂ H Q9c 268. Cl Cl OCH₂CH₂ H Q9d269. Cl Cl OCH₂CH₂ H Q10a 270. Cl Cl OCH₂CH₂ H Q11a 271. Cl Cl OCH₂CH₂ HQ12 272. Cl Cl OCH₂CH₂ H Q13 46-54 273. Cl Cl OCH₂CH₂ H Q14 274. Cl ClOCH₂CH₂ H Q15 275. Cl Cl OCH₂CH₂ Me Q1a 1.5908 276. Cl Cl OCH₂CH₂ Me Q1b1.5475 277. Cl Cl OCH₂CH₂ Me Q1c 278. Cl Cl OCH₂CH₂ Me Q1d 1.5741 279.Cl Cl OCH₂CH₂ Me Q1e 280. Cl Cl OCH₂CH₂ Me Q2a 281. Cl Cl OCH₂CH₂ Me Q2b282. Cl Cl OCH₂CH₂ Me Q3a 283. Cl Cl OCH₂CH₂ Me Q3b 284. Cl Cl OCH₂CH₂Me Q3c 285. Cl Cl OCH₂CH₂ Me Q3d 286. Cl Cl OCH₂CH₂ Me Q3e 287. Cl ClOCH₂CH₂ Me Q3f 288. Cl Cl OCH₂CH₂ Me Q3g 289. Cl Cl OCH₂CH₂ Me Q3h 290.Cl Cl OCH₂CH₂ Me Q3i 291. Cl Cl OCH₂CH₂ Me Q3j 292. Cl Cl OCH₂CH₂ Me Q3k293. Cl Cl OCH₂CH₂ Me Q31 294. Cl Cl OCH₂CH₂ Me Q3m 295. Cl Cl OCH₂CH₂Me Q3n 296. Cl Cl OCH₂CH₂ Me Q3o 297. Cl Cl OCH₂CH₂ Me Q3p 298. Cl ClOCH₂CH₂ Me Q3q 299. Cl Cl OCH₂CH₂ Me Q3r 300. Cl Cl OCH₂CH₂ Me Q3s 301.Cl Cl OCH₂CH₂ Me Q3t 302. Cl Cl OCH₂CH₂ Me Q3u 303. Cl Cl OCH₂CH₂ Me Q3v304. Cl Cl OCH₂CH₂ Me Q3w 305. Cl Cl OCH₂CH₂ Me Q3x 306. Cl Cl OCH₂CH₂Me Q3y 307. Cl Cl OCH₂CH₂ Me Q3z 308. Cl Cl OCH₂CH₂ Me Q3za 309. Cl ClOCH₂CH₂ Me Q3zb 310. Cl Cl OCH₂CH₂ Me Q3zc 311. Cl Cl OCH₂CH₂ Me Q3zd312. Cl Cl OCH₂CH₂ Me Q4a 313. Cl Cl OCH₂CH₂ Me Q4b 314. Cl Cl OCH₂CH₂Me Q4c 315. Cl Cl OCH₂CH₂ Me Q4d 316. Cl Cl OCH₂CH₂ Me Q5a 317. Cl ClOCH₂CH₂ Me Q5b 318. Cl Cl OCH₂CH₂ Me Q5c 319. Cl Cl OCH₂CH₂ Me Q6b 320.Cl Cl OCH₂CH₂ Me Q7 321. Cl Cl OCH₂CH₂ Me Q8a 322. Cl Cl OCH₂CH₂ Me Q8b323. Cl Cl OCH₂CH₂ Me Q8c 324. Cl Cl OCH₂CH₂ Me Q8d 325. Cl Cl OCH₂CH₂Me Q9a 326. Cl Cl OCH₂CH₂ Me Q9b 327. Cl Cl OCH₂CH₂ Me Q9c 328. Cl ClOCH₂CH₂ Me Q9d 329. Cl Cl OCH₂CH₂ Me Q10a 330. Cl Cl OCH₂CH₂ Me Q11a331. Cl Cl OCH₂CH₂ Me Q12 332. Cl Cl OCH₂CH₂ Me Q13 333. Cl Cl OCH₂CH₂Me Q14 334. Cl Cl OCH₂CH₂ Me Q15 335. Cl Cl OCH₂CH₂ Et Q1a 336. Cl ClOCH₂CH₂ Et Q1b 337. Cl Cl OCH₂CH₂ Et Q1c 338. Cl Cl OCH₂CH₂ Et Q1d 339.Cl Cl OCH₂CH₂ Et Q1e 340. Cl Cl OCH₂CH₂ Et Q2a 341. Cl Cl OCH₂CH₂ Et Q2b342. Cl Cl OCH₂CH₂ Et Q3a 343. Cl Cl OCH₂CH₂ Et Q3c 344. Cl Cl OCH₂CH₂Et Q4a 345. Cl Cl OCH₂CH₂ Et Q5a 346. Cl Cl OCH₂CH₂ Et Q6a 347. Cl ClOCH₂CH₂ Et Q8a 348. Cl Cl OCH₂CH₂ Et Q8d 349. Cl Cl OCH₂CH₂ Et Q9a 350.Cl Cl OCH₂CH₂ Et Q12 351. Cl Cl OCH₂CH₂ Et Q13 352. Cl Cl OCH₂CH₂ n-PrQ1a 353. Cl Cl OCH₂CH₂ n-Pr Q3a 354. Cl Cl OCH₂CH₂ n-Pr Q6a 355. Cl ClOCH₂CH₂ SMe Q7a 1.6028 356. Cl Cl OCH₂CH₂ SMe Q8a 357. Cl Cl OCH₂CH₂ SMeQ6a 358. Cl Cl OCH₂CH(Me) H Q1a 359. Cl Cl OCH₂CH(Me) H Q1b 360. Cl ClOCH₂CH(Me) H Q1c 361. Cl Cl OCH₂CH(Me) H Q1d 362. Cl Cl OCH₂CH(Me) H Q1e363. Cl Cl OCH₂CH(Me) H Q2a 364. Cl Cl OCH₂CH(Me) H Q2b 365. Cl ClOCH₂CH(Me) H Q3a 366. Cl Cl OCH₂CH(Me) H Q3c 367. Cl Cl OCH₂CH(Me) H Q4a368. Cl Cl OCH₂CH(Me) H Q5a 369. Cl Cl OCH₂CH(Me) H Q6a 370. Cl ClOCH₂CH(Me) H Q8a 371. Cl Cl OCH₂CH(Me) H Q8d 372. Cl Cl OCH₂CH(Me) H Q9a373. Cl Cl OCH₂CH(Me) H Q12 374. Cl Cl OCH₂CH(Me) H Q13 375. Cl ClOCH₂CH(Me) Me Q1a 376. Cl Cl OCH₂CH(Me) Me Q3a 377. Cl Cl OCH₂CH(Me) MeQ6a 378. Cl Cl OCH₂CH₂CH₂ H Q1a 379. Cl Cl OCH₂CH₂CH₂ H Q1b 380. Cl ClOCH₂CH₂CH₂ H Q1c 381. Cl Cl OCH₂CH₂CH₂ H Q1d 382. Cl Cl OCH₂CH₂CH₂ H Q1e383. Cl Cl OCH₂CH₂CH₂ H Q2a 384. Cl Cl OCH₂CH₂CH₂ H Q2b 385. Cl ClOCH₂CH₂CH₂ H Q3a 386. Cl Cl OCH₂CH₂CH₂ H Q3c 387. Cl Cl OCH₂CH₂CH₂ H Q4a388. Cl Cl OCH₂CH₂CH₂ H Q5a 389. Cl Cl OCH₂CH₂CH₂ H Q6a 390. Cl ClOCH₂CH₂CH₂ H Q8a 391. Cl Cl OCH₂CH₂CH₂ H Q8d 392. Cl Cl OCH₂CH₂CH₂ H Q9a393. Cl Cl OCH₂CH₂CH₂ H Q12 394. Cl Cl OCH₂CH₂CH₂ H Q13 395. Cl ClOCH₂CH₂CH₂ Me Q1a 396. Cl Cl OCH₂CH₂CH₂ Me Q3a 397. Cl Cl OCH₂CH₂CH₂ MeQ6a 398. Cl Cl CH(Me) H Q1a 399. Cl Cl CH(Me)CH₂ H Q1a 400. Cl ClCH₂CH₂CH₂ H Q1a 401. Cl Cl OCH₂ H Q1a 402. Cl Cl OCH(Me)CH₂ H Q1a 403.Cl Cl(Me) OCH₂CH₂ H Q1a 404. Cl Cl(Me) OCH₂CH₂ H Q2a 405. Cl Cl(Me)OCH₂CH₂ H Q2b 406. Cl Cl(Me) OCH₂CH₂ H Q3a 407. Cl Cl(Me) OCH₂CH₂ H Q6a408. Cl Cl(Me) OCH₂CH₂ H Q8d 409. Cl Cl(Me) OCH₂CH₂ Me Q1a 410. ClCl(Me) OCH₂CH₂ Me Q2a 411. Cl Cl(Me) OCH₂CH₂ Me Q2b 412. Cl Cl(Me)OCH₂CH₂ Me Q3a 413. Cl Cl(Me) OCH₂CH₂ Me Q6a 414. Cl Cl(Me) OCH₂CH₂ MeQ8d 415. Cl Br CH₂ H Q1a 416. Cl Br CF₂ Me Q1a 417. Cl Br OCH₂CH₂ H Q1a418. Cl Br OCH₂CH₂ H Q1b 419. Cl Br OCH₂CH₂ H Q1c 420. Cl Br OCH₂CH₂ HQ1d 421. Cl Br OCH₂CH₂ H Q1e 422. Cl Br OCH₂CH₂ H Q2a 423. Cl Br OCH₂CH₂H Q2b 424. Cl Br OCH₂CH₂ H Q3a 425. Cl Br OCH₂CH₂ H Q3c 426. Cl BrOCH₂CH₂ H Q4a 427. Cl Br OCH₂CH₂ H Q5a 428. Cl Br OCH₂CH₂ H Q6a 429. ClBr OCH₂CH₂ H Q8a 430. Cl Br OCH₂CH₂ H Q8d 431. Cl Br OCH₂CH₂ H Q9a 432.Cl Br OCH₂CH₂ H Q12 433. Cl Br OCH₂CH₂ H Q13 434. Cl Br OCH₂CH₂ Me Q1a435. Cl Br OCH₂CH₂ Me Q3a 436. Cl Br OCH₂CH₂ Me Q6a 437. Cl BrOCH₂CH(Me) H Q1a 438. Cl Br OCH₂CH₂CH₂ H Q1a 439. Cl I OCH₂CH₂ H Q1a440. Cl I OCH₂CH₂ Me Q1a 441. Cl Me OCH₂CH₂ H Q1a 442. Cl Me OCH₂CH₂ HQ1b 443. Cl Me OCH₂CH₂ H Q1c 444. Cl Me OCH₂CH₂ H Q1d 445. Cl Me OCH₂CH₂H Q1e 446. Cl Me OCH₂CH₂ H Q2a 447. Cl Me OCH₂CH₂ H Q2b 448. Cl MeOCH₂CH₂ H Q3a 449. Cl Me OCH₂CH₂ H Q3c 450. Cl Me OCH₂CH₂ H Q4a 451. ClMe OCH₂CH₂ H Q5a 452. Cl Me OCH₂CH₂ H Q6a 453. Cl Me OCH₂CH₂ H Q8a 454.Cl Me OCH₂CH₂ H Q8d 455. Cl Me OCH₂CH₂ H Q9a 456. Cl Me OCH₂CH₂ H Q12457. Cl Me OCH₂CH₂ H Q13 458. Cl Me OCH₂CH₂ Me Q1a 459. Cl Me OCH₂CH₂ MeQ2a 460. Cl Me OCH₂CH₂ Me Q2b 461. Cl Me OCH₂CH₂ Me Q3a 462. Cl MeOCH₂CH₂ Me Q6a 463. Cl Me OCH₂CH₂ Me Q8d 464. Cl Me OCH₂CH(Me) H Q1a465. Cl Me OCH₂CH₂CH₂ H Q1a 466. Cl CF₃ OCH₂CH₂ H Q1a 467. Cl CF₃OCH₂CH₂ H Q2a 468. Cl CF₃ OCH₂CH₂ H Q2b 469. Cl CF₃ OCH₂CH₂ H Q3a 470.Cl CF₃ OCH₂CH₂ Me Q1a 471. Cl CF₃ OCH₂CH₂ Me Q3a 472. Cl CF₃ OCH₂CH₂CH₂H Q1a 473. Cl CF₃ OCH₂CH₂CH₂ Me Q1a 474. Cl OMe CH₂ H Q1a 156-157 475.Cl OMe CH₂ H Q3a 476. Cl OMe CH₂ Me Q1a 477. Cl OSO₂Me CH₂ H Q1a 478. ClOSO₂Et CH₂ H Q1a 479. Cl SMe CH₂ H Q1a 480. Cl SMe CH₂ H Q3a 481. Cl SMeCH₂ Me Q1a 482. Cl SMe OCH₂CH₂ H Q1a 483. Cl SMe OCH₂CH₂ H Q2a 484. ClSMe OCH₂CH₂ H Q2b 485. Cl SMe OCH₂CH₂ H Q3a 486. Cl SMe OCH₂CH₂ H Q6a487. Cl SMe OCH₂CH₂ H Q8d 488. Cl SMe OCH₂CH₂ Me Q1a 489. Cl SMe OCH₂CH₂Me Q3a 490. Cl SMe OCH₂CH(Me) H Q1a 491. Cl SMe OCH₂CH₂CH₂ H Q1a 492. ClSEt CH₂ H Q1a 493. Cl SEt OCH₂CH₂ H Q1a 494. Cl SEt OCH₂CH₂ Me Q1a 495.Cl SO₂Me CH₂ H Q1a 213-216 496. Cl SO₂Me CH₂ H Q1b 497. Cl SO₂Me CH₂ HQ1c 498. Cl SO₂Me CH₂ H Q1d 499. Cl SO₂Me CH₂ H Q1e 500. Cl SO₂Me CH₂ HQ2a 501. Cl SO₂Me CH₂ H Q2b 502. Cl SO₂Me CH₂ H Q3a 216-218 503. ClSO₂Me CH₂ H Q3b 504. Cl SO₂Me CH₂ H Q3c 505. Cl SO₂Me CH₂ H Q3d 506. ClSO₂Me CH₂ H Q3e 507. Cl SO₂Me CH₂ H Q3f 508. Cl SO₂Me CH₂ H Q3g 509. ClSO₂Me CH₂ H Q3h 510. Cl SO₂Me CH₂ H Q3i 511. Cl SO₂Me CH₂ H Q3j 512. ClSO₂Me CH₂ H Q3k 513. Cl SO₂Me CH₂ H Q31 514. Cl SO₂Me CH₂ H Q3m 515. ClSO₂Me CH₂ H Q3n 516. Cl SO₂Me CH₂ H Q3o 517. Cl SO₂Me CH~ H Q3p 518. ClSO₂Me CH₂ H Q3q 519. Cl SO₂Me CH₂ H Q3r 520. Cl SO₂Me CH₂ H Q3s 521. ClSO₂Me CH₂ H Q3t 522. Cl SO₂Me CH₂ H Q3u 523. Cl SO₂Me CH₂ H Q3v 524. ClSO₂Me CH₂ H Q3w 525. Cl SO₂Me CH₂ H Q3x 526. Cl SO₂Me CH₂ H Q3y 527. ClSO₂Me CH₂ H Q3z 528. Cl SO₂Me CH₂ H Q3za 529. Cl SO₂Me CH₂ H Q3zb 530.Cl SO₂Me CH₂ H Q3zc 531. Cl SO₂Me CH₂ H Q3zd 532. Cl SO₂Me CH₂ H Q4a533. Cl SO₂Me CH₂ H Q4b 534. Cl SO₂Me CH₂ H Q4c 535. Cl SO₂Me CH₂ H Q4d536. Cl SO₂Me CH₂ H Q5a 537. Cl SO₂Me CH₂ H Q5b 538. Cl SO₂Me CH₂ H Q5c539. Cl SO₂Me CH₂ H Q5d 540. Cl SO₂Me CH₂ H QSe 541. Cl SO₂Me CH₂ H Q6a82-85 542. Cl SO₂Me CH₂ H Q6b 543. Cl SO₂Me CH₂ H Q7 544. Cl SO₂Me CH₂ HQ8a 545. Cl SO₂Me CH₂ H Q8b 546. Cl SO₂Me CH₂ H Q8c 547. Cl SO₂Me CH₂ HQ8d 548. Cl SO₂Me CH₂ H Q9a 549. Cl SO₂Me CH₂ H Q9b 550. Cl SO₂Me CH₂ HQ9c 551. Cl SO₂Me CH₂ H Q9d 552. Cl SO₂Me CH₂ H Q10a 553. Cl SO₂Me CH₂ HQ11a 554. Cl SO₂Me CH₂ H Q12 555. Cl SO₂Me CH₂ H Q13 556. Cl SO₂Me CH₂ HQ14 557. Cl SO₂Me CH₂ H Q15 558. Cl SO₂Me CH₂ Me Q1a 85-89 559. Cl SO₂MeCH₂ Me Q1b 560. Cl SO₂Me CH₂ Me Q1c 561. Cl SO₂Me CH₂ Me Q1d 562. ClSO₂Me CH₂ Me Q1e 563. Cl SO₂Me CH₂ Me Q2a 564. Cl SO₂Me CH₂ Me Q2b 565.Cl SO₂Me CH₂ Me Q3a 566. Cl SO₂Me CH₂ Me Q3b 567. Cl SO₂Me CH₂ Me Q3c568. Cl SO₂Me CH₂ Me Q3d 569. Cl SO₂Me CH₂ Me Q3e 570. Cl SO₂Me CH₂ MeQ3f 571. Cl SO₂Me CH₂ Me Q3g 572. Cl SO₂Me CH₂ Me Q3h 573. Cl SO₂Me CH₂Me Q3i 574. Cl SO₂Me CH₂ Me Q3j 575. Cl SO₂Me CH₂ Me Q3k 576. Cl SO₂MeCH₂ Me Q31 577. Cl SO₂Me CH₂ Me Q3m 578. Cl SO₂Me CH₂ Me Q3n 579. ClSO₂Me CH₂ Me Q3o 580. Cl SO₂Me CH₂ Me Q3p 581. Cl SO₂Me CH₂ Me Q3q 582.Cl SO₂Me CH₂ Me Q3r 583. Cl SO₂Me CH₂ Me Q3s 584. Cl SO₂Me CH₂ Me Q3t585. Cl SO₂Me CH₂ Me Q3u 586. Cl SO₂Me CH₂ Me Q3v 587. Cl SO₂Me CH₂ MeQ3w 588. Cl SO₂Me CH₂ Me Q3x 589. Cl SO₂Me CH₂ Me Q3y 590. Cl SO₂Me CH₂Me Q3z 591. Cl SO₂Me CH₂ Me Q3za 592. Cl SO₂Me CH₂ Me Q3zb 593. Cl SO₂MeCH₂ Me Q3zc 594. Cl SO₂Me CH₂ Me Q3zd 595. Cl SO₂Me CH₂ Me Q4a 596. ClSO₂Me CH₂ Me Q4b 597. Cl SO₂Me CH₂ Me Q4c 598. Cl SO₂Me CH₂ Me Q4d 599.Cl SO₂Me CH₂ Me Q5a 600. Cl SO₂Me CH₂ Me QSb 601. Cl SO₂Me CH₂ Me QSc602. Cl SO₂Me CH₂ Me Q6b 603. Cl SO₂Me CH₂ Me Q7 604. Cl SO₂Me CH₂ MeQ8a 605. Cl SO₂Me CH₂ Me Q8b 606. Cl SO₂Me CH₂ Me Q8c 607. Cl SO₂Me CH₂Me QSd 608. Cl SO₂Me CH₂ Me Q9a 609. Cl SO₂Me CH₂ Me Q9b 610. Cl SO₂MeCH₂ Me Q9c 611. Cl SO₂Me CH₂ Me Q9d 612. Cl SO₂Me CH₂ Me Q10a 613. ClSO₂Me CH₂ Me Q11a 614. Cl SO₂Me CH₂ Me Q12 615. Cl SO₂Me CH₂ Me Q13 616.Cl SO₂Me CH₂ Et Q1a 617. Cl SO₂Me CH₂ Et Q1b 618. Cl SO₂Me CH₂ Et Q1c619. Cl SO₂Me CH₂ Et Q1d 620. Cl SO₂Me CH₂ Et Q1e 621. Cl SO₂Me CH₂ EtQ2a 622. Cl SO₂Me CH₂ Et Q2b 623. Cl SO₂Me CH₂ Et Q3a 624. Cl SO₂Me CH₂Et Q3c 625. Cl SO₂Me CH₂ Et Q4a 626. Cl SO₂Me CH₂ Et Q5a 627. Cl SO₂MeCH₂ Et Q6a 628. Cl SO₂Me CH₂ Et Q8a 629. Cl SO₂Me CH₂ Et Q8d 630. ClSO₂Me CH₂ Et Q9a 631. Cl SO₂Me CH₂ Et Q12 632. Cl SO₂Me CH₂ Et Q13 633.Cl SO₂Me CH₂ n-Pr Q1a 634. Cl SO₂Me CH₂ n-Pr Q1b 635. Cl SO₂Me CH₂ n-PrQ1c 636. Cl SO₂Me CH₂ n-Pr Q1d 637. Cl SO₂Me CH₂ n-Pr Q1e 638. Cl SO₂MeCH₂ n-Pr Q2a 639. Cl SO₂Me CH₂ n-Pr Q2b 640. Cl SO₂Me CH₂ n-Pr Q3a 641.Cl SO₂Me CH₂ n-Pr Q3c 642. Cl SO₂Me CH₂ n-Pr Q4a 643. Cl SO₂Me CH₂ n-PrQ5a 644. Cl SO₂Me CH₂ n-Pr Q6a 645. Cl SO₂Me CH₂ n-Pr Q8a 646. Cl SO₂MeCH₂ n-Pr Q8d 647. Cl SO₂Me CH₂ n-Pr Q9a 648. Cl SO₂Me CH₂ n-Pr Q12 649.Cl SO₂Me CH₂ n-Pr Q13 650. Cl SO₂Me CH₂ SMe Q1a 92-97 651. Cl SO₂Me CH₂SMe Q1b 652. Cl SO₂Me CH₂ SMe Q1c 653. Cl SO₂Me CH₂ SMe Q1d 654. ClSO₂Me CH₂ SMe Q1e 655. Cl SO₂Me CH₂ SMe Q2a 656. Cl SO₂Me CH₂ SMe Q2b657. Cl SO₂Me CH₂ SMe Q3a 658. Cl SO₂Me CH₂ SMe Q3c 659. Cl SO₂Me CH₂SMe Q4a 660. Cl SO₂Me CH₂ SMe Q5a 661. Cl SO₂Me CH₂ SMe Q6a 662. ClSO₂Me CH₂ SMe Q8a 663. Cl SO₂Me CH₂ SMe Q8d 664. Cl SO₂Me CH₂ SMe Q9a665. Cl SO₂Me CH₂ SMe Q12 666. Cl SO₂Me CH₂ SMe Q13 667. Cl SO₂Me CH₂n-Bu Q1a 668. Cl SO₂Me CH₂ n-Pen Q1a 669. Cl SO₂Me CH₂ n-Hex Q1a 670. ClSO₂Me CH₂ cyclo-Pr Q1a 671. Cl SO₂Me CH₂ cyclo-Bu Q1a 672. Cl SO₂Me CH₂cyclo-Pen Q1a 673. Cl SO₂Me CH₂ cyclo-Hex Q1a 674. Cl SO₂Me CH₂ CH₂CH₂Q1a 675. Cl SO₂Me CH₂ CH₂CH∇CH₂ Q1a 676. Cl SO₂Me CH₂ C≡CH Q1a 677. ClSO₂Me CH₂ CF₃ Q1a 678. Cl SO₂Me CH₂ CH₂CH₂Cl Q1a 679. Cl SO₂Me CH₂CH₂CH₂CH₂ Q1a Br 680. Cl SO₂Me CH₂ SEt Q1a 681. Cl SO₂Me CH₂ S-n-Pr Q1a682. Cl SO₂Me CH₂ Ph Q1a 683. Cl SO₂Me CH₂ 2-Cl-Ph Q1a 684. Cl SO₂Me CH₂3-Cl-Ph Q1a 685. Cl SO₂Me CH₂ 2-Me-Ph Q1a 686. Cl SO₂Me CH₂ 4-Me-Ph Q1a687. Cl SO₂Me CH₂ 3-Et-Ph Q1a 688. Cl SO₂Me CH₂ 4-n-Pr-Ph Q1a 689. ClSO₂Me CH₂ 3-CF₃-Ph Q1a 690. Cl SO₂Me CH₂ 3-CH₂CF₃- Q1a Ph 691. Cl SO₂MeCH₂ 3-NO₂-Ph Q1a 692. Cl SO₂Me CH₂CH₂ H Q1a 693. Cl SO₂Me CH₂CH₂ H Q1b694. Cl SO₂Me CH₂CH₂ H Q1c 695. Cl SO₂Me CH₂CH₂ H Q1d 696. Cl SO₂MeCH₂CH₂ H Q1e 697. Cl SO₂Me CH₂CH₂ H Q2a 698. Cl SO₂Me CH₂CH₂ H Q2b 699.Cl SO₂Me CH₂CH₂ H Q3a 700. Cl SO₂Me CH₂CH₂ H Q3c 701. Cl SO₂Me CH₂CH₂ HQ4a 702. Cl SO₂Me CH₂CH₂ H Q5a 703. Cl SO₂Me CH₂CH₂ H Q6a 704. Cl SO₂MeCH₂CH₂ H Q8a 705. Cl SO₂Me CH₂CH₂ H Q8d 706. Cl SO₂Me CH₂CH₂ H Q9a 707.Cl SO₂Me CH₂CH₂ H Q12 708. Cl SO₂Me CH₂CH₂ H Q13 709. Cl SO₂Me CH₂CH₂ MeQ1a 710. Cl SO₂Me CH₂CH₂ Me Q2a 711. Cl SO₂Me CH₂CH₂ Me Q2b 712. ClSO₂Me CH₂CH₂ Me Q3a 713. Cl SO₂Me CH₂CH₂ Me Q6a 714. Cl SO₂Me CH₂CH₂ MeQ8d 715. Cl SO₂Me OCH₂CH₂ H Q1a 78-81 716. Cl SO₂Me OCH₂CH₂ H Q1b 717.Cl SO₂Me OCH₂CH₂ H Q1c 718. Cl SO₂Me OCH₂CH₂ H Q1d 719. Cl SO₂Me OCH₂CH₂H Q1e 720. Cl SO₂Me OCH₂CH₂ H Q2a 721. Cl SO₂Me OCH₂CH₂ H Q2b 722. ClSO₂Me OCH₂CH₂ H Q3a 723. Cl SO₂Me OCH₂CH₂ H Q3b 724. Cl SO₂Me OCH₂CH₂ HQ3c 725. Cl SO₂Me OCH₂CH₂ H Q3d 726. Cl SO₂Me OCH₂CH₂ H Q3e 727. ClSO₂Me OCH₂CH₂ H Q3f 728. Cl SO₂Me OCH₂CH₂ H Q3g 729. Cl SO₂Me OCH₂CH₂ HQ3h 730. Cl SO₂Me OCH₂CH₂ H Q3i 731. Cl SO₂Me OCH₂CH₂ H Q3j 732. ClSO₂Me OCH₂CH₂ H Q3k 733. Cl SO₂Me OCH₂CH₂ H Q31 734. Cl SO₂Me OCH₂CH₂ HQ3m 735. Cl SO₂Me OCH₂CH₂ H Q3n 736. Cl SO₂Me OCH₂CH₂ H Q3o 737. ClSO₂Me OCH₂CH₂ H Q3p 738. Cl SO₂Me OCH₂CH₂ H Q3q 739. Cl SO₂Me OCH₂CH₂ HQ3r 740. Cl SO₂Me OCH₂CH₂ H Q3s 741. Cl SO₂Me OCH₂CH₂ H Q3t 742. ClSO₂Me OCH₂CH₂ H Q3u 743. Cl SO₂Me OCH₂CH₂ H Q3v 744. Cl SO₂Me OCH₂CH₂ HQ3w 745. Cl SO₂Me OCH₂CH₂ H Q3x 746. Cl SO₂Me OCH₂CH₂ H Q3y 747. ClSO₂Me OCH₂CH₂ H Q3z 748. Cl SO₂Me OCH₂CH₂ H Q3za 749. Cl SO₂Me OCH₂CH₂ HQ3zb 750. Cl SO₂Me OCH₂CH₂ H Q3zc 751. Cl SO₂Me OCH₂CH₂ H Q3zd 752. ClSO₂Me OCH₂CH₂ H Q4a 753. Cl SO₂Me OCH₂CH₂ H Q4b 754. Cl SO₂Me OCH₂CH₂ HQ4c 755. Cl SO₂Me OCH₂CH₂ H Q4d 756. Cl SO₂Me OCH₂CH₂ H Q5a 757. ClSO₂Me OCH₂CH₂ H Q5b 758. Cl SO₂Me OCH₂CH₂ H Q5c 759. Cl SO₂Me OCH₂CH₂ HQ5d 760. Cl SO₂Me OCH₂CH₂ H Q5e 761. Cl SO₂Me OCH₂CH₂ H Q6a 762. ClSO₂Me OCH₂CH₂ H Q6b 763. Cl SO₂Me OCH₂CH₂ H Q7 764. Cl SO₂Me OCH₂CH₂ HQ8a 765. Cl SO₂Me OCH₂CH₂ H Q8b 766. Cl SO₂Me OCH₂CH₂ H Q8c 767. ClSO₂Me OCH₂CH₂ H Q8d 768. Cl SO₂Me OCH₂CH₂ H Q9a 769. Cl SO₂Me OCH₂CH₂ HQ9b 770. Cl SO₂Me OCH₂CH₂ H Q9c 771. Cl SO₂Me OCH₂CH₂ H Q9d 772. ClSO₂Me OCH₂CH₂ H Q10a 773. Cl SO₂Me OCH₂CH₂ H Q11a 774. Cl SO₂Me OCH₂CH₂H Q12 775. Cl SO₂Me OCH₂CH₂ H Q13 776. Cl SO₂Me OCH₂CH₂ Me Q1a 75-80777. Cl SO₂Me OCH₂CH₂ Me Q1b 778. Cl SO₂Me OCH₂CH₂ Me Q1c 779. Cl SO₂MeOCH₂CH₂ Me Q1d 780. Cl SO₂Me OCH₂CH₂ Me Q1e 781. Cl SO₂Me OCH₂CH₂ Me Q2a782. Cl SO₂Me OCH₂CH₂ Me Q2b 783. Cl SO₂Me OCH₂CH₂ Me Q3a 784. Cl SO₂MeOCH₂CH₂ Me Q3b 785. Cl SO₂Me OCH₂CH₂ Me Q3c 786. Cl SO₂Me OCH₂CH₂ Me Q3d787. Cl SO₂Me OCH₂CH₂ Me Q3e 788. Cl SO₂Me OCH₂CH₂ Me Q3f 789. Cl SO₂MeOCH₂CH₂ Me Q3g 790. Cl SO₂Me OCH₂CH₂ Me Q3h 791. Cl SO₂Me OCH₂CH₂ Me Q31792. Cl SO₂Me OCH₂CH₂ Me Q3j 793. Cl SO₂Me OCH₂CH₂ Me Q3k 794. Cl SO₂MeOCH₂CH₂ Me Q31 795. Cl SO₂Me OCH₂CH₂ Me Q3m 796. Cl SO₂Me OCH₂CH₂ Me Q3n797. Cl SO₂Me OCH₂CH₂ Me Q3o 798. Cl SO₂Me OCH₂CH₂ Me Q3p 799. Cl SO₂MeOCH₂CH₂ Me Q3q 800. Cl SO₂Me OCH₂CH₂ Me Q3r 801. Cl SO₂Me OCH₂CH₂ Me Q3s802. Cl SO₂Me OCH₂CH₂ Me Q3t 803. Cl SO₂Me OCH₂CH₂ Me Q3u 804. Cl SO₂MeOCH₂CH₂ Me Q3v 805. Cl SO₂Me OCH₂CH₂ Me Q3w 806. Cl SO₂Me OCH₂CH₂ Me Q3x807. Cl SO₂Me OCH₂CH₂ Me Q3y 808. Cl SO₂Me OCH₂CH₂ Me Q3z 809. Cl SO₂MeOCH₂CH₂ Me Q3za 810. Cl SO₂Me OCH₂CH₂ Me Q3zb 811. Cl SO₂Me OCH₂CH₂ MeQ3zc 812. Cl SO₂Me OCH₂CH₂ Me Q3zd 813. Cl SO₂Me OCH₂CH₂ Me Q4a 814. ClSO₂Me OCH₂CH₂ Me Q4b 815. Cl SO₂Me OCH₂CH₂ Me Q4c 816. Cl SO₂Me OCH₂CH₂Me Q4d 817. Cl SO₂Me OCH₂CH₂ Me Q5a 818. Cl SO₂Me OCH₂CH₂ Me Q5b 819. ClSO₂Me OCH₂CH₂ Me Q5c 820. Cl SO₂Me OCH₂CH₂ Me Q6a 821. Cl SO₂Me OCH₂CH₂Me Q6b 822. Cl SO₂Me OCH₂CH₂ Me Q7 823. Cl SO₂Me OCH₂CH₂ Me Q8a 824. ClSO₂Me OCH₂CH₂ Me Q8b 825. Cl SO₂Me OCH₂CH₂ Me Q8c 826. Cl SO₂Me OCH₂CH₂Me Q8d 827. Cl SO₂Me OCH₂CH₂ Me Q9a 828. Cl SO₂Me OCH₂CH₂ Me Q9b 829. ClSO₂Me OCH₂CH₂ Me Q9c 830. Cl SO₂Me OCH₂CH₂ Me Q9d 831. Cl SO₂Me OCH₂CH₂Me Q10a 832. Cl SO₂Me OCH₂CH₂ Me Q11a 833. Cl SO₂Me OCH₂CH₂ Me Q12 834.Cl SO₂Me OCH₂CH₂ Et Q1a 835. Cl SO₂Me OCH₂CH₂ Et Q1b 836. Cl SO₂MeOCH₂CH₂ Et Q1c 837. Cl SO₂Me OCH₂CH₂ Et Q1d 838. Cl SO₂Me OCH₂CH₂ Et Q1e839. Cl SO₂Me OCH₂CH₂ Et Q2a 840. Cl SO₂Me OCH₂CH₂ Et Q2b 841. Cl SO₂MeOCH₂CH₂ Et Q3a 842. Cl SO₂Me OCH₂CH₂ Et Q3c 843. Cl SO₂Me OCH₂CH₂ Et Q4a844. Cl SO₂Me OCH₂CH₂ Et Q5a 845. Cl SO₂Me OCH₂CH₂ Et Q6a 846. Cl SO₂MeOCH₂CH₂ Et Q8a 847. Cl SO₂Me OCH₂CH₂ Et Q8d 848. Cl SO₂Me OCH₂CH₂ Et Q9a849. Cl SO₂Me OCH₂CH₂ Et Q12 850. Cl SO₂Me OCH₂CH₂ Et Q13 851. Cl SO₂MeOCH₂CH₂ n-Pr Q1a 852. Cl SO₂Me OCH₂CH₂ n-Pr Q3a 853. Cl SO₂Me OCH₂CH₂n-Pr Q6a 854. Cl SO₂Me OCH₂CH₂ SMe Q1a 855. Cl SO₂Me OCH₂CH₂ SMe Q3a856. Cl SO₂Me OCH₂CH₂ SMe Q6a 857. Cl SO₂Me OCH₂CH₂ n-Bu Q1a 858. ClSO₂Me OCH₂CH₂ n-Pen Q1a 859. Cl SO₂Me OCH₂CH₂ n-Hex Q1a 860. Cl SO₂MeOCH₂CH₂ cyclo-Pr Q1a 861. Cl SO₂Me OCH₂CH₂ cyclo-Bu Q1a 862. Cl SO₂MeOCH₂CH₂ cyclo-Pen Q1a 863. Cl SO₂Me OCH₂CH₂ cyclo-Hex Q1a 864. Cl SO₂MeOCH₂CH₂ SEt Q1a 865. Cl SO₂Me OCH₂CH₂ S-n-Pr Q1a 866. Cl SO₂Me OCH₂CH₂Ph Q1a 867. Cl SO₂Me OCH₂CH₂ 2-Cl-Ph Q1a 868. Cl SO₂Me OCH₂CH₂ 3-Cl-PhQ1a 869. Cl SO₂Me OCH₂CH₂ 2-Me-Ph Q1a 870. Cl SO₂Me OCH₂CH₂ 4-Me-Ph Q1a871. Cl SO₂Me OCH₂CH₂ 3-Et-Ph Q1a 872. Cl SO₂Me OCH₂CH₂ 4-n-Pr-Ph Q1a873. Cl SO₂Me OCH₂CH₂ 3-CF₃-Ph Q1a 874. Cl SO₂Me OCH₂CH₂ 3-CH₂CF₃- Q1aPh 875. Cl SO₂Me OCH₂CH₂ 3-NO₂-Ph Q1a 876. Cl SO₂Me OCH₂CH(Me) H Q1a877. Cl SO₂Me OCH₂CH(Me) H Q1b 878. Cl SO₂Me OCH₂CH(Me) H Q1c 879. ClSO₂Me OCH₂CH(Me) H Q1d 880. Cl SO₂Me OCH₂CH(Me) H Q1e 881. Cl SO₂MeOCH₂CH(Me) H Q2a 882. Cl SO₂Me OCH₂CH(Me) H Q2b 883. Cl SO₂Me OCH₂CH(Me)H Q3a 884. Cl SO₂Me OCH₂CH(Me) H Q3c 885. Cl SO₂Me OCH₂CH(Me) H Q4a 886.Cl SO₂Me OCH₂CH(Me) H Q5a 887. Cl SO₂Me OCH₂CH(Mc) H Q6a 888. Cl SO₂MeOCH₂CH(Me) H Q8a 889. Cl SO₂Me OCH₂CH(Me) H Q8d 890. Cl SO₂Me OCH₂CH(Me)H Q9a 891. Cl SO₂Me OCH₂CH(Me) H Q12 892. Cl SO₂Me OCH₂CH(Me) H Q13 893.Cl SO₂Me OCH₂CH(Me) Me Q1a 894. Cl SO₂Me OCH₂CH(Me) Me Q3a 895. Cl SO₂MeOCH₂CH(Me) Me Q6a 896. Cl SO₂Me OCH₂CH₂CH₂ H Q1a 897. Cl SO₂MeOCH₂CH₂CH₂ H Q1b 898. Cl SO₂Me OCH₂CH₂CH₂ H Q1c 899. Cl SO₂Me OCH₂CH₂CH₂H Q1d 900. Cl SO₂Me OCH₂CH₂CH₂ H Q1e 901. Cl SO₂Me OCH₂CH₂CH₂ H Q2a 902.Cl SO₂Me OCH₂CH₂CH₂ H Q2b 903. Cl SO₂Me OCH₂CH₂CH₂ H Q3a 904. Cl SO₂MeOCH₂CH₂CH₂ H Q3c 905. Cl SO₂Me OCH₂CH₂CH₂ H Q4a 906. Cl SO₂Me OCH₂CH₂CH₂H Q5a 907. Cl SO₂Me OCH₂CH₂CH₂ H Q6a 908. Cl SO₂Me OCH₂CH₂CH₂ H Q8a 909.Cl SO₂Me OCH₂CH₂CH₂ H Q8d 910. Cl SO₂Me OCH₂CH₂CH₂ H Q9a 911. Cl SO₂MeOCH₂CH₂CH₂ H Q12 912. Cl SO₂Me OCH₂CH₂CH₂ H Q13 913. Cl SO₂Me OCH₂CH₂CH₂Me Q1a 914. Cl SO₂Me OCH₂CH₂CH₂ Me Q2a 915. Cl SO₂Me OCH₂CH₂CH₂ Me Q2b916. Cl SO₂Me OCH₂CH₂CH₂ Me Q3a 917. Cl SO₂Me OCH₂CH₂CH₂ Me Q6a 918. ClSO₂Me OCH₂CH₂CH₂ Me Q13 919. Cl SO₂Me CH(Me) H Q1a 920. Cl SO₂MeCH(Me)CH₂ H Q1a 921. Cl SO₂Me CH₂CH₂CH₂ H Q1a 922. Cl SO₂Me OCH₂ H Q1a923. Cl SO₂Me OCH₂ Me Q1a 924. Cl SO₂Me OCH(Me)CH₂ H Q1a 925. Cl SO₂MeOCH(Me)CH₂ Me Q1a 926. Cl SO₂Et CH₂ H Q1a 927. Cl SO₂Et CH₂ H Q1b 928.Cl SO₂Et CH₂ H Q1c 929. Cl SO₂Et CH₂ H Q1d 930. Cl SO₂Et CH₂ H Q1e 931.Cl SO₂Et CH₂ H Q2a 932. Cl SO₂Et CH₂ H Q2b 933. Cl SO₂Et CH₂ H Q3a 934.Cl SO₂Et CH₂ H Q3c 935. Cl SO₂Et CH₂ H Q4a 936. Cl SO₂Et CH₂ H Q5a 937.Cl SO₂Et CH₂ H Q6a 938. Cl SO₂Et CH₂ H Q8a 939. Cl SO₂Et CH₂ H Q8d 940.Cl SO₂Et CH₂ H Q9a 941. Cl SO₂Et CH₂ H Q12 942. Cl SO₂Et CH₂ H Q13 943.Cl SO₂Et CH₂ Me Q1a 944. Cl SO₂Et CH₂ Me Q2a 945. Cl SO₂Et CH₂ Me Q2b946. Cl SO₂Et CH₂ Me Q3a 947. Cl SO₂Et CH₂ Me Q6a 948. Cl SO₂Et CH₂ MeQ8d 949. Cl SO₂Et CH₂CH₂ H Q1a 950. Cl SO₂Et CH₂CH₂ Me Q1a 951. Cl SO₂EtOCH₂CH₂ H Q1a 952. Cl SO₂Et OCH₂CH₂ H Q1b 953. Cl SO₂Et OCH₂CH₂ H Q1c954. Cl SO₂Et OCH₂CH₂ H Q1d 955. Cl SO₂Et OCH₂CH₂ H Q1e 956. Cl SO₂EtOCH₂CH₂ H Q2a 957. Cl SO₂Et OCH₂CH₂ H Q2b 958. Cl SO₂Et OCH₂CH₂ H Q3a959. Cl SO₂Et OCH₂CH₂ H Q3c 960. Cl SO₂Et OCH₂CH₂ H Q4a 961. Cl SO₂EtOCH₂CH₂ H Q5a 962. Cl SO₂Et OCH₂CH₂ H Q6a 963. Cl SO₂Et OCH₂CH₂ H Q8a964. Cl SO₂Et OCH₂CH₂ H Q8d 965. Cl SO₂Et OCH₂CH₂ H Q9a 966. Cl SO₂EtOCH₂CH₂ H Q12 967. Cl SO₂Et OCH₂CH₂ H Q13 968. Cl SO₂Et OCH₂CH₂ Me Q1a969. Cl SO₂Et OCH₂CH₂ Me Q2a 970. Cl SO₂Et OCH₂CH₂ Me Q2b 971. Cl SO₂EtOCH₂CH₂ Me Q3a 972. Cl SO₂Et OCH₂CH₂ Me Q6a 973. Cl SO₂Et OCH₂CH₂ Me Q8d974. Cl SO₂Et OCH₂CH(Me) H Q1a 975. Cl SO₂Et OCH₂CH₂CH₂ H Q1a 976. ClSO₂Pr-n CH₂ H Q1a 977. Cl SO₂Pr-n OCH₂CH₂ H Q1a 978. Cl SO₂Pr-n OCH₂CH₂Me Q1a 979. Cl NO₂ CH₂ H Q1a 980. Cl NO₂ CH₂ H Q3a 981. Cl NO₂ CH₂ MeQ1a 982. Cl NO₂ OCH₂CH₂ H Q1a 983. Cl NO₂ OCH₂CH₂ H Q1b 984. Cl NO₂OCH₂CH₂ H Q1c 985. Cl NO₂ OCH₂CH₂ H Q1d 986. Cl NO₂ OCH₂CH₂ H Q1e 987.Cl NO₂ OCH₂CH₂ H Q2a 988. Cl NO₂ OCH₂CH₂ H Q2b 989. Cl NO₂ OCH₂CH₂ H Q3a990. Cl NO₂ OCH₂CH₂ H Q3c 991. Cl NO₂ OCH₂CH₂ H Q4a 992. Cl NO₂ OCH₂CH₂H Q5a 993. Cl NO₂ OCH₂CH₂ H Q6a 994. Cl NO₂ OCH₂CH₂ H Q8a 995. Cl NO₂OCH₂CH₂ H Q8d 996. Cl NO₂ OCH₂CH₂ H Q9a 997. Cl NO₂ OCH₂CH₂ H Q12 998.Cl NO₂ OCH₂CH₂ H Q13 999. Cl NO₂ OCH₂CH₂ Me Q1a 1000. Cl NO₂ OCH₂CH₂ MeQ2a 1001. Cl NO₂ OCH₂CH₂ Me Q2b 1002. Cl NO₂ OCH₂CH₂ Me Q3a 1003. Cl NO₂OCH₂CH₂ Me Q6a 1004. Cl NO₂ OCH₂CH₂ Me Q8d 1005. Cl NO₂ OCH₂CH(Me) H Q1a1006. Cl NO₂ OCH₂CH₂CH₂ H Q1a 1007. Br F OCH₂CH₂ H Q1a 1008. Br FOCH₂CH₂ H Q1b 1009. Br F OCH₂CH₂ H Q1c 1010. Br F OCH₂CH₂ H Q1d 1011. BrF OCH₂CH₂ H Q1e 1012. Br F OCH₂CH₂ H Q2a 1013. Br F OCH₂CH₂ H Q2b 1014.Br F OCH₂CH₂ H Q3a 1015. Br F OCH₂CH₂ H Q3c 1016. Br F OCH₂CH₂ H Q4a1017. Br F OCH₂CH₂ H Q5a 1018. Br F OCH₂CH₂ H Q6a 1019. Br F OCH₂CH₂ HQ8a 1020. Br F OCH₂CH₂ H Q8d 1021. Br F OCH₂CH₂ H Q9a 1022. Br F OCH₂CH₂H Q12 1023. Br F OCH₂CH₂ H Q13 1024. Br F OCH₂CH₂ Me Q1a 1025. Br FOCH₂CH₂ Me Q2a 1026. Br F OCH₂CH₂ Me Q2b 1027. Br F OCH₂CH₂ Me Q3a 1028.Br F OCH₂CH₂ Me Q6a 1029. Br F OCH₂CH₂ Me Q8d 1030. Br F OCH₂CH(Me) HQ1a 1031. Br F OCH₂CH₂CH₂ H Q1a 1032. Br F OCH₂CH₂CH₂ H Q3a 1033. Br ClOCH₂CH₂ H Q1a 1034. Br Cl OCH₂CH₂ H Q1b 1035. Br Cl OCH₂CH₂ H Q1c 1036.Br Cl OCH₂CH₂ H Q1d 1037. Br Cl OCH₂CH₂ H Q1e 1038. Br Cl OCH₂CH₂ H Q2a1039. Br Cl OCH₂CH₂ H Q2b 1040. Br Cl OCH₂CH₂ H Q3a 1041. Br Cl OCH₂CH₂H Q3c 1042. Br Cl OCH₂CH₂ H Q4a 1043. Br Cl OCH₂CH₂ H Q5a 1044. Br ClOCH₂CH₂ H Q6a 1045. Br Cl OCH₂CH₂ H Q8a 1046. Br Cl OCH₂CH₂ H Q8d 1047.Br Cl OCH₂CH₂ H Q9a 1048. Br Cl OCH₂CH₂ H Q12 1049. Br Cl OCH₂CH₂ H Q131050. Br Cl OCH₂CH₂ Me Q1a 1051. Br Cl OCH₂CH₂ Me Q2a 1052. Br ClOCH₂CH₂ Me Q2b 1053. Br Cl OCH₂CH₂ Me Q3a 1054. Br Cl OCH₂CH₂ Me Q6a1055. Br Cl OCH₂CH₂ Me Q8d 1056. Br Cl OCH₂CH(Me) H Q1a 1057. Br ClOCH₂CH₂CH₂ H Q1a 1058. Br Cl OCH₂CH₂CH₂ H Q3a 1059. Br Br CH₂ H Q1a70-74 1060. Br Br CH₂ H Q1b 1061. Br Br CH₂ H Q1c 1062. Br Br CH₂ H Q1d1063. Br Br CH₂ H Q1e 1064. Br Br CH₂ H Q2a 1065. Br Br CH₂ H Q2b 1066.Br Br CH₂ H Q3a 163-168 1067. Br Br CH₂ H Q3b 1068. Br Br CH₂ H Q3c1069. Br Br CH₂ H Q3d 1070. Br Br CH₂ H Q3e 1071. Br Br CH₂ H Q3f 1072.Br Br CH₂ H Q3g 1073. Br Br CH₂ H Q3h 1074. Br Br CH₂ H Q3i 1075. Br BrCH₂ H Q3j 1076. Br Br CH₂ H Q3k 1077. Br Br CH₂ H Q31 1078. Br Br CH₂ HQ3m 1079. Br Br CH₂ H Q3n 1080. Br Br CH₂ H Q3o 1081. Br Br CH₂ H Q3p1082. Br Br CH₂ H Q3q 1083. Br Br CH₂ H Q3r 1084. Br Br CH₂ H Q3s 1085.Br Br CH₂ H Q3t 1086. Br Br CH₂ H Q3u 1087. Br Br CH₂ H Q3v 1088. Br BrCH₂ H Q3w 1089. Br Br CH₂ H Q3x 1090. Br Br CH₂ H Q3y 1091. Br Br CH₂ HQ3z 1092. Br Br CH₂ H Q3za 1093. Br Br CH₂ H Q3zb 1094. Br Br CH₂ H Q3zc1095. Br Br CH₂ H Q3zd 1096. Br Br CH₂ H Q4a 1097. Br Br CH₂ H Q4b 1098.Br Br CH₂ H Q4c 1099. Br Br CH₂ H Q4d 1100. Br Br CH₂ H Q5a 1101. Br BrCH₂ H Q5b 1102. Br Br CH₂ H Q5c 1103. Br Br CH₂ H Q6a 1104. Br Br CH₂ HQ6b 1105. Br Br CH₂ H Q7 1106. Br Br CH₂ H Q8a 1107. Br Br CH₂ H Q8b1108. Br Br CH₂ H Q8c 1109. Br Br CH₂ H Q8d 1110. Br Br CH₂ H Q9a 1111.Br Br CH₂ H Q9b 1112. Br Br CH₂ H Q9c 1113. Br Br CH₂ H Q9d 1114. Br BrCH₂ H Q10a 1115. Br Br CH₂ H Q11a 1116. Br Br CH₂ H Q12 1117. Br Br CH₂H Q13 1118. Br Br CH₂ Me Q1a 1119. Br Br CH₂ Me Q1b 1120. Br Br CH₂ MeQ1c 1121. Br Br CH₂ Me Q1d 1122. Br Br CH₂ Me Q1e 1123. Br Br CH₂ Me Q2a1124. Br Br CH₂ Me Q2b 1125. Br Br CH₂ Me Q3a 1126. Br Br CH₂ Me Q3b1127. Br Br CH₂ Me Q3c 1128. Br Br CH₂ Me Q3d 1129. Br Br CH₂ Me Q3e1130. Br Br CH₂ Me Q3f 1131. Br Br CH₂ Me Q3g 1132. Br Br CH₂ Me Q3h1133. Br Br CH₂ Me Q3i 1134. Br Br CH₂ Me Q3j 1135. Br Br CH₂ Me Q3k1136. Br Br CH₂ Me Q31 1137. Br Br CH₂ Me Q3m 1138. Br Br CH₂ Me Q3n1139. Br Br CH₂ Me Q3o 1140. Br Br CH₂ Me Q3p 1141. Br Br CH₂ Me Q3q1142. Br Br CH₂ Me Q3r 1143. Br Br CH₂ Me Q3s 1144. Br Br CH₂ Me Q3t1145. Br Br CH₂ Me Q3u 1146. Br Br CH₂ Me Q3v 1147. Br Br CH₂ Me Q3w1148. Br Br CH₂ Me Q3x 1149. Br Br CH₂ Me Q3y 1150. Br Br CH₂ Me Q3z1151. Br Br CH₂ Me Q3za 1152. Br Br CH₂ Me Q3zb 1153. Br Br CH₂ Me Q3zc1154. Br Br CH₂ Me Q3zd 1155. Br Br CH₂ Me Q4a 1156. Br Br CH₂ Me Q4b1157. Br Br CH₂ Me Q4c 1158. Br Br CH₂ Me Q4d 1159. Br Br CH₂ Me QSa1160. Br Br CH₂ Me Q6a 1161. Br Br CH₂ Me Q6b 1162. Br Br CH₂ Me Q71163. Br Br CH₂ Me Q8a 1164. Br Br CH₂ Me Q8b 1165. Br Br CH₂ Me Q8c1166. Br Br CH₂ Me Q8d 1167. Br Br CH₂ Me Q9a 1168. Br Br CH₂ Me Q9b1169. Br Br CH₂ Me Q9c 1170. Br Br CH₂ Me Q9d 1171. Br Br CH₂ Me Q10a1172. Br Br CH₂ Me Q11a 1173. Br Br CH₂ Me Q12 1174. Br Br CH₂ Me Q131175. Br Br CH₂ Et Q1a 1176. Br Br CH₂ Et Q1b 1177. Br Br CH₂ Et Q1c1178. Br Br CH₂ Et Q1d 1179. Br Br CH₂ Et Q1e 1180. Br Br CH₂ Et Q2a1181. Br Br CH₂ Et Q2b 1182. Br Br CH₂ Et Q3a 1183. Br Br CH₂ Et Q3c1184. Br Br CH₂ Et Q4a 1185. Br Br CH₂ Et Q5a 1186. Br Br CH₂ Et Q6a1187. Br Br CH₂ Et Q8a 1188. Br Br CH₂ Et Q8d 1189. Br Br CH₂ Et Q9a1190. Br Br CH₂ Et Q12 1191. Br Br CH₂ Et Q13 1192. Br Br CH₂ n-Pr Q1a1193. Br Br CH₂ n-Pr Q3a 1194. Br Br CH₂ n-Pr Q6a 1195. Br Br CH₂ SMeQ1a 1196. Br Br CH₂ SMe Q1b 1197. Br Br CH₂ SMe Q1c 1198. Br Br CH₂ SMeQ1d 1199. Br Br CH₂ SMe Q1e 1200. Br Br CH₂ SMe Q2a 1201. Br Br CH₂ SMeQ2b 1202. Br Br CH₂ SMe Q3a 1203. Br Br CH₂ SMe Q3c 1204. Br Br CH₂ SMeQ4a 1205. Br Br CH₂ SMe Q5a 1206. Br Br CH₂ SMe Q6a 1207. Br Br CH₂ SMeQ8a 1208. Br Br CH₂ SMe Q8d 1209. Br Br CH₂ SMe Q9a 1210. Br Br CH₂ SMeQ12 1211. Br Br CH₂ SMe Q13 1212. Br Br CH₂CH₂ H Q1a 1213. Br Br CH₂CH₂H Q1b 1214. Br Br CH₂CH₂ H Q1c 1215. Br Br CH₂CH₂ H Q1d 1216. Br BrCH₂CH₂ H Q1e 1217. Br Br CH₂CH₂ H Q2a 1218. Br Br CH₂CH₂ H Q2b 1219. BrBr CH₂CH₂ H Q3a 1220. Br Br CH₂CH₂ H Q3c 1221. Br Br CH₂CH₂ H Q4a 1222.Br Br CH₂CH₂ H Q5a 1223. Br Br CH₂CH₂ H Q6a 1224. Br Br CH₂CH₂ H Q8a1225. Br Br CH₂CH₂ H Q8d 1226. Br Br CH₂CH₂ H Q9a 1227. Br Br CH₂CH₂ HQ12 1228. Br Br CH₂CH₂ H Q13 1229. Br Br CH₂CH₂ Me Q1a 1230. Br BrCH₂CH₂ Me Q2a 1231. Br Br CH₂CH₂ Me Q2b 1232. Br Br CH₂CH₂ Me Q3a 1233.Br Br CH₂CH₂ Me Q6a 1234. Br Br OCH₂CH₂ H Q1a 64-68 1235. Br Br OCH₂CH₂H Q1b 1236. Br Br OCH₂CH₂ H Q1c 1237. Br Br OCH₂CH₂ H Q1d 1238. Br BrOCH₂CH₂ H Q1e 1239. Br Br OCH₂CH₂ H Q2a 1.6035 1240. Br Br OCH₂CH₂ H Q2b1241. Br Br OCH₂CH₂ H Q3a 1242. Br Br OCH₂CH₂ H Q3b 1243. Br Br OCH₂CH₂H Q3c 1244. Br Br OCH₂CH₂ H Q3d 1245. Br Br OCH₂CH₂ H Q3e 1246. Br BrOCH₂CH₂ H Q3f 1247. Br Br OCH₂CH₂ H Q3g 1248. Br Br OCH₂CH₂ H Q3h 1249.Br Br OCH₂CH₂ H Q3i 1250. Br Br OCH₂CH₂ H Q3j 1251. Br Br OCH₂CH₂ H Q3k1252. Br Br OCH₂CH₂ H Q31 1253. Br Br OCH₂CH₂ H Q3m 1254. Br Br OCH₂CH₂H Q3n 1255. Br Br OCH₂CH₂ H Q3o 1256. Br Br OCH₂CH₂ H Q3p 1257. Br BrOCH₂CH₂ H Q3q 1258. Br Br OCH₂CH₂ H Q3r 1259. Br Br OCH₂CH₂ H Q3s 1260.Br Br OCH₂CH₂ H Q3t 1261. Br Br OCH₂CH₂ H Q3u 1262. Br Br OCH₂CH₂ H Q3v1263. Br Br OCH₂CH₂ H Q3w 1264. Br Br OCH₂CH₂ H Q3x 1265. Br Br OCH₂CH₂H Q3y 1266. Br Br OCH₂CH₂ H Q3z 1267. Br Br OCH₂CH₂ H Q3za 1268. Br BrOCH₂CH₂ H Q3zb 1269. Br Br OCH₂CH₂ H Q3zc 1270. Br Br OCH₂CH₂ H Q3zd1271. Br Br OCH₂CH₂ H Q4a 1272. Br Br OCH₂CH₂ H Q4b 1273. Br Br OCH₂CH₂H Q4c 1274. Br Br OCH₂CH₂ H Q4d 1275. Br Br OCH₂CH₂ H Q5a 1276. Br BrOCH₂CH₂ H Q5b 1277. Br Br OCH₂CH₂ H Q5c 1278. Br Br OCH₂CH₂ H Q5d 1279.Br Br OCH₂CH₂ H Q5e 1280. Br Br OCH₂CH₂ H Q6a 1281. Br Br OCH₂CH₂ H Q6b1282. Br Br OCH₂CH₂ H Q7 1283. Br Br OCH₂CH₂ H Q8a 1284. Br Br OCH₂CH₂ HQ8b 1285. Br Br OCH₂CH₂ H Q8c 1286. Br Br OCH₂CH₂ H Q8d 1287. Br BrOCH₂CH₂ H Q9a 1288. Br Br OCH₂CH₂ H Q9b 1289. Br Br OCH₂CH₂ H Q9c 1290.Br Br OCH₂CH₂ H Q9d 1291. Br Br OCH₂CH₂ H Q10a 1292. Br Br OCH₂CH₂ HQ11a 1293. Br Br OCH₂CH₂ H Q12 1294. Br Br OCH₂CH₂ H Q13 1295. Br BrOCH₂CH₂ Me Q1a 1296. Br Br OCH₂CH₂ Me Q1b 1297. Br Br OCH₂CH₂ Me Q1c1298. Br Br OCH₂CH₂ Me Q1d 1299. Br Br OCH₂CH₂ Me Q1e 1300. Br BrOCH₂CH₂ Me Q2a 1301. Br Br OCH₂CH₂ Me Q2b 1302. Br Br OCH₂CH₂ Me Q3a1303. Br Br OCH₂CH₂ Me Q3b 1304. Br Br OCH₂CH₂ Me Q3c 1305. Br BrOCH₂CH₂ Me Q3d 1306. Br Br OCH₂CH₂ Me Q3e 1307. Br Br OCH₂CH₂ Me Q3f1308. Br Br OCH₂CH₂ Me Q3g 1309. Br Br OCH₂CH₂ Me Q3h 1310. Br BrOCH₂CH₂ Me Q3i 1311. Br Br OCH₂CH₂ Me Q3j 1312. Br Br OCH₂CH₂ Me Q3k1313. Br Br OCH₂CH₂ Me Q31 1314. Br Br OCH₂CH₂ Me Q3m 1315. Br BrOCH₂CH₂ Me Q3n 1316. Br Br OCH₂CH₂ Me Q3o 1317. Br Br OCH₂CH₂ Me Q3p1318. Br Br OCH₂CH₂ Me Q3q 1319. Br Br OCH₂CH₂ Me Q3r 1320. Br BrOCH₂CH₂ Me Q3s 1321. Br Br OCH₂CH₂ Me Q3t 1322. Br Br OCH₂CH₂ Me Q3u1323. Br Br OCH₂CH₂ Me Q3v 1324. Br Br OCH₂CH₂ Me Q3w 1325. Br BrOCH₂CH₂ Me Q3x 1326. Br Br OCH₂CH₂ Me Q3y 1327. Br Br OCH₂CH₂ Me Q3z1328. Br Br OCH₂CH₂ Me Q3za 1329. Br Br OCH₂CH₂ Me Q3zb 1330. Br BrOCH₂CH₂ Me Q3zc 1331. Br Br OCH₂CH₂ Me Q3zd 1332. Br Br OCH₂CH₂ Me Q4a1333. Br Br OCH₂CH₂ Me Q4b 1334. Br Br OCH₂CH₂ Me Q4c 1335. Br BrOCH₂CH₂ Me Q4d 1336. Br Br OCH₂CH₂ Me Q5a 1337. Br Br OCH₂CH₂ Me Q5b1338. Br Br OCH₂CH₂ Me Q5c 1339. Br Br OCH₂CH₂ Me Q6a 1340. Br BrOCH₂CH₂ Me Q6b 1341. Br Br OCH₂CH₂ Me Q7 1342. Br Br OCH₂CH₂ Me Q8a1343. Br Br OCH₂CH₂ Me Q8b 1344. Br Br OCH₂CH₂ Me Q8c 1345. Br BrOCH₂CH₂ Me Q8d 1346. Br Br OCH₂CH₂ Me Q9a 1347. Br Br OCH₂CH₂ Me Q9b1348. Br Br OCH₂CH₂ Me Q9c 1349. Br Br OCH₂CH₂ Me Q9d 1350. Br BrOCH₂CH₂ Me Q10a 1351. Br Br OCH₂CH₂ Me Q11a 1352. Br Br OCH₂CH₂ Me Q121353. Br Br OCH₂CH₂ Me Q13 1354. Br Br OCH₂CH₂ Et Q1a 1355. Br BrOCH₂CH₂ Et Q1b 1356. Br Br OCH₂CH₂ Et Q1c 1357. Br Br OCH₂CH₂ Et Q1d1358. Br Br OCH₂CH₂ Et Q1e 1359. Br Br OCH₂CH₂ Et Q2a 1360. Br BrOCH₂CH₂ Et Q2b 1361. Br Br OCH₂CH₂ Et Q3a 1362. Br Br OCH₂CH₂ Et Q3c1363. Br Br OCH₂CH₂ Et Q4a 1364. Br Br OCH₂CH₂ Et Q5a 1365. Br BrOCH₂CH₂ Et Q6a 1366. Br Br OCH₂CH₂ Et Q8a 1367. Br Br OCH₂CH₂ Et Q8d1368. Br Br OCH₂CH₂ Et Q9a 1369. Br Br OCH₂CH₂ Et Q12 1370. Br BrOCH₂CH₂ Et Q13 1371. Br Br OCH₂CH₂ n-Pr Q1a 1372. Br Br OCH₂CH₂ n-Pr Q3a1373. Br Br OCH₂CH₂ n-Pr Q6a 1374. Br Br OCH₂CH₂ SMe Q1a 1375. Br BrOCH₂CH₂ SMe Q3a 1376. Br Br OCH₂CH₂ SMe Q6a 1377. Br Br OCH₂CH(Me) H Q1a1378. Br Br OCH₂CH(Me) H Q1b 1379. Br Br OCH₂CH(Me) H Q1c 1380. Br BrOCH₂CH(Me) H Q1d 1381. Br Br OCH₂CH(Me) H Q1e 1382. Br Br OCH₂CH(Me) HQ2a 1383. Br Br OCH₂CH(Me) H Q2b 1384. Br Br OCH₂CH(Me) H Q3a 1385. BrBr OCH₂CH(Me) H Q3c 1386. Br Br OCH₂CH(Me) H Q4a 1387. Br Br OCH₂CH(Me)H Q5a 1388. Br Br OCH₂CH(Me) H Q6a 1389. Br Br OCH₂CH(Me) H Q8a 1390. BrBr OCH₂CH(Me) H Q8d 1391. Br Br OCH₂CH(Me) H Q9a 1392. Br Br OCH₂CH(Me)H Q12 1393. Br Br OCH₂CH(Me) H Q13 1394. Br Br OCH₂CH(Me) Me Q1a 1395.Br Br OCH₂CH(Me) Me Q3a 1396. Br Br OCH₂CH(Me) Me Q6a 1397. Br BrOCH₂CH₂CH₂ H Q1a 1398. Br Br OCH₂CH₂CH₂ H Q1b 1399. Br Br OCH₂CH₂CH₂ HQ1c 1400. Br Br OCH₂CH₂CH₂ H Q1d 1401. Br Br OCH₂CH₂CH₂ H Q1e 1402. BrBr OCH₂CH₂CH₂ H Q2a 1403. Br Br OCH₂CH₂CH₂ H Q2b 1404. Br Br OCH₂CH₂CH₂H Q3a 1405. Br Br OCH₂CH₂CH₂ H Q3c 1406. Br Br OCH₂CH₂CH₂ H Q4a 1407. BrBr OCH₂CH₂CH₂ H Q5a 1408. Br Br OCH₂CH₂CH₂ H Q6a 1409. Br Br OCH₂CH₂CH₂H Q8a 1410. Br Br OCH₂CH₂CH₂ H Q8d 1411. Br Br OCH₂CH₂CH₂ H Q9a 1412. BrBr OCH₂CH₂CH₂ H Q12 1413. Br Br OCH₂CH₂CH₂ H Q13 1414. Br Br OCH₂CH₂CH₂Me Q1a 1415. Br Br OCH₂CH₂CH₂ Me Q3a 1416. Br Br OCH₂CH₂CH₂ Me Q6a 1417.Br Br CH(Me) H Q1a 1418. Br Br CH(Me)CH₂ H Q1a 1419. Br Br OCH₂ H Q1a1420. Br Br OCH(Me)CH₂ H Q1a 1421. Br Br(Me) OCH₂CH₂ H Q1a 1422. BrBr(Me) OCH₂CH₂ H Q2a 1423. Br Br(Me) OCH₂CH₂ H Q2b 1424. Br Br(Me)OCH₂CH₂ H Q3a 1425. Br Br(Me) OCH₂CH₂ H Q6a 1426. Br Br(Me) OCH₂CH₂ HQ8d 1427. Br Br(Me) OCH₂CH₂ Me Q1a 1428. Br Br(Me) OCH₂CH₂ Me Q2a 1429.Br Br(Me) OCH₂CH₂ Me Q2b 1430. Br Br(Me) OCH₂CH₂ Me Q3a 1431. Br Br(Me)OCH₂CH₂ Me Q6a 1432. Br Br(Me) OCH₂CH₂ Me Q8d 1433. Br I OCH₂CH₂ H Q1a1434. Br I OCH₂CH₂ H Q2a 1435. Br I OCH₂CH₂ H Q2b 1436. Br I OCH₂CH₂ HQ3a 1437. Br I OCH₂CH₂ H Q6a 1438. Br I OCH₂CH₂ H Q8d 1439. Br I OCH₂CH₂Me Q1a 1440. Br I OCH₂CH₂ Me Q2a 1441. Br I OCH₂CH₂ Me Q2b 1442. Br IOCH₂CH₂ Me Q6a 1443. Br I OCH(Me)CH₂ H Q1a 1444. Br I OCH₂CH₂CH₂ H Q1a1445. Br Me OCH₂CH₂ H Q1a 1446. Br Me OCH₂CH₂ H Q1b 1447. Br Me OCH₂CH₂H Q1c 1448. Br Me OCH₂CH₂ H Q1d 1449. Br Me OCH₂CH₂ H Q1e 1450. Br MeOCH₂CH₂ H Q2a 1451. Br Me OCH₂CH₂ H Q2b 1452. Br Me OCH₂CH₂ H Q3a 1453.Br Me OCH₂CH₂ H Q3c 1454. Br Me OCH₂CH₂ H Q4a 1455. Br Me OCH₂CH₂ H Q5a1456. Br Me OCH₂CH₂ H Q6a 1457. Br Me OCH₂CH₂ H Q8a 1458. Br Me OCH₂CH₂H Q8d 1459. Br Me OCH₂CH₂ H Q9a 1460. Br Me OCH₂CH₂ H Q12 1461. Br MeOCH₂CH₂ H Q13 1462. Br Me OCH₂CH₂ Me Q1a 1463. Br Me OCH₂CH₂ Me Q2a1464. Br Me OCH₂CH₂ Me Q2b 1465. Br Me OCH₂CH₂ Me Q3a 1466. Br MeOCH₂CH₂ Me Q6a 1467. Br Me OCH₂CH₂ Me Q8d 1468. Br Me OCH₂CH(Me) H Q1a1469. Br Me OCH₂CH₂CH₂ H Q1a 1470. Br CN OCH₂CH₂ H Q1a 1471. Br CNOCH₂CH₂ H Q3a 1472. Br CN OCH₂CH₂ H Q4a 1473. Br CN OCH₂CH₂ Me Q1a 1474.Br CN OCH₂CH₂ Me Q3a 1475. Br CN OCH₂CH₂ Me Q4a 1476. Br CF₃ OCH₂CH₂ HQ1a 1477. Br CF₃ OCH₂CH₂ H Q2a 1478. Br CF₃ OCH₂CH₂ H Q2b 1479. Br CF₃OCH₂CH₂ H Q3a 1480. Br CF₃ OCH₂CH₂ Me Q1a 1481. Br CF₃ OCH₂CH₂ Me Q3a1482. Br CF₃ OCH₂CH₂CH₂ H Q1a 1483. Br CF₃ OCH₂CH₂CH₂ Me Q1a 1484. BrSO₂Me CH₂ H Q1a 1485. Br SO₂Me CH₂ H Q1b 1486. Br SO₂Me CH₂ H Q1c 1487.Br SO₂Me CH₂ H Q1d 1488. Br SO₂Me CH₂ H Q1e 1489. Br SO₂Me CH₂ H Q2a1490. Br SO₂Me CH₂ H Q2b 1491. Br SO₂Me CH₂ H Q3a 1492. Br SO₂Me CH₂ HQ3c 1493. Br SO₂Me CH₂ H Q4a 1494. Br SO₂Me CH₂ H Q5a 1495. Br SO₂Me CH₂H Q6a 1496. Br SO₂Me CH₂ H Q8a 1497. Br SO₂Me CH₂ H Q8d 1498. Br SO₂MeCH₂ H Q9a 1499. Br SO₂Me CH₂ H Q12 1500. Br SO₂Me CH₂ H Q13 1501. BrSO₂Me CH₂ Me Q1a 1502. Br SO₂Me CH₂ Me Q2a 1503. Br SO₂Me CH₂ Me Q2b1504. Br SO₂Me CH₂ Me Q3a 1505. Br SO₂Me CH₂ Me Q6a 1506. Br SO₂Me CH₂Me Q8d 1507. Br SO₂Me CH₂ Et Q1a 1508. Br SO₂Me CH₂ n-Pr Q1a 1509. BrSO₂Me CH₂ SMe Q1a 1510. Br SO₂Me CH₂CH₂ H Q1a 1511. Br SO₂Me CH₂CH₂ MeQ1a 1512. Br SO₂Me OCH₂CH₂ H Q1a 1513. Br SO₂Me OCH₂CH₂ H Q1b 1514. BrSO₂Me OCH₂CH₂ H Q1c 1515. Br SO₂Me OCH₂CH₂ H Q1d 1516. Br SO₂Me OCH₂CH₂H Q1e 1517. Br SO₂Me OCH₂CH₂ H Q2a 1518. Br SO₂Me OCH₂CH₂ H Q2b 1519. BrSO₂Me OCH₂CH₂ H Q3a 1520. Br SO₂Me OCH₂CH₂ H Q3c 1521. Br SO₂Me OCH₂CH₂H Q4a 1522. Br SO₂Me OCH₂CH₂ H Q5a 1523. Br SO₂Me OCH₂CH₂ H Q6a 1524. BrSO₂Me OCH₂CH₂ H Q8a 1525. Br SO₂Me OCH₂CH₂ H Q8d 1526. Br SO₂Me OCH₂CH₂H Q9a 1527. Br SO₂Me OCH₂CH₂ H Q12 1528. Br SO₂Me OCH₂CH₂ H Q13 1529. BrSO₂Me OCH₂CH₂ Me Q1a 1530. Br SO₂Me OCH₂CH₂ Me Q2a 1531. Br SO₂MeOCH₂CH₂ Me Q2b 1532. Br SO₂Me OCH₂CH₂ Me Q3a 1533. Br SO₂Me OCH₂CH₂ MeQ6a 1534. Br SO₂Me OCH₂CH₂ Me Q8d 1535. Br SO₂Me OCH₂CH₂ Et Q1a 1536. BrSO₂Me OCH₂CH₂ n-Pr Q1a 1537. Br SO₂Me OCH₂CH₂ SMe Q1a 1538. Br SO₂MeOCH₂CH(Me) H Q1a 1539. Br SO₂Me OCH₂CH₂CH₂ H Q1a 1540. Br SO₂MeOCH₂CH₂CH₂ Me Q1a 1541. I I OCH₂CH₂ H Q1a 1542. I I OCH₂CH₂ H Q2a 1543.I I OCH₂CH₂ H Q2b 1544. I I OCH₂CH₂ H Q3a 1545. I I OCH₂CH₂ H Q6a 1546.I I OCH₂CH₂ H Q8d 1547. I I OCH₂CH₂ Me Q1a 1548. I I OCH₂CH₂ Me Q3a1549. I I OCH₂CH₂ Me Q6a 1550. I I OCH₂CH(Me) H Q1a 1551. I I OCH₂CH₂CH₂H Q1a 1552. Me Cl OCH₂CH₂ H Q1a 1553. Me Cl OCH₂CH₂ H Q1b 1554. Me ClOCH₂CH₂ H Q1c 1555. Me Cl OCH₂CH₂ H Q1d 1556. Me Cl OCH₂CH₂ H Q1e 1557.Me Cl OCH₂CH₂ H Q2a 1558. Me Cl OCH₂CH₂ H Q2b 1559. Me Cl OCH₂CH₂ H Q3a1560. Me Cl OCH₂CH₂ H Q3c 1561. Me Cl OCH₂CH₂ H Q4a 1562. Me Cl OCH₂CH₂H QSa 1563. Me Cl OCH₂CH₂ H Q6a 1564. Me Cl OCH₂CH₂ H Q8a 1565. Me ClOCH₂CH₂ H Q8d 1566. Me Cl OCH₂CH₂ H Q9a 1567. Me Cl OCH₂CH₂ H Q12 1568.Me Cl OCH₂CH₂ H Q13 1569. Me Cl OCH₂CH₂ Me Q1a 1570. Me Cl OCH₂CH₂ MeQ2a 1571. Me Cl OCH₂CH₂ Me Q2b 1572. Me Cl OCH₂CH₂ Me Q3a 1573. Me ClOCH₂CH₂ Me Q6a 1574. Me Cl OCH₂CH₂ Me Q8d 1575. Me Cl OCH₂CH(Me) H Q1a1576. Me Cl OCH₂CH₂CH₂ H Q1a 1577. Me Br OCH₂CH₂ H Q1a 1.5938 1578. MeBr OCH₂CH₂ H Q1b 1579. Me Br OCH₂CH₂ H Q1c 1580. Me Br OCH₂CH₂ H Q1d1581. Me Br OCH₂CH₂ H Q1e 1582. Me Br OCH₂CH₂ H Q2a 63-66 1583. Me BrOCH₂CH₂ H Q2b 1584. Me Br OCH₂CH₂ H Q3a 68-70 1585. Me Br OCH₂CH₂ H Q3c1586. Me Br OCH₂CH₂ H Q4a 1587. Me Br OCH₂CH₂ H Q5a 1588. Me Br OCH₂CH₂H Q6a 1589. Me Br OCH₂CH₂ H Q8a 1590. Me Br OCH₂CH₂ H Q8d 1591. Me BrOCH₂CH₂ H Q9a 1592. Me Br OCH₂CH₂ H Q12 1593. Me Br OCH₂CH₂ H Q13154-155 1594. Me Br OCH₂CH₂ Me Q1a 65-70 1595. Me Br OCH₂CH₂ Me Q2a1596. Me Br OCH₂CH₂ Me Q2b 1597. Me Br OCH₂CH₂ Me Q3a 1598. Me BrOCH₂CH₂ Me Q6a 1599. Me Br OCH₂CH₂ Me Q8d 1600. Me Br OCH₂CH(Me) H Q1a1601. Me Br OCH₂CH₂CH₂ H Q1a 1602. Me I OCH₂CH₂ H Q1a 1603. Me I OCH₂CH₂H Q3a 1604. Me I OCH₂CH₂ H Q6a 1605. Me I OCH₂CH₂ H Q8d 1606. Me IOCH₂CH₂ Me Q1a 1607. Me I OCH₂CH₂ Me Q3a 1608. Me I OCH₂CH₂ Me Q6a 1609.Me I OCH₂CH(Me) H Q1a 1610. Me I OCH₂CH₂CH₂ H Q1a 1611. Me SMe OCH₂CH₂ HQ1a 1612. Me SMe OCH₂CH₂ H Q3a 1613. Me SMe OCH₂CH₂ H Q6a 1614. Me SMeOCH₂CH₂ H Q8d 1615. Me SMe OCH₂CH₂ Me Q1a 1616. Me SMe OCH₂CH₂ Me Q3a1617. Me SMe OCH₂CH₂ Me Q6a 1618. Me SMe OCH₂CH(Me) H Q1a 1619. Me SMeOCH₂CH₂CH₂ H Q1a 1620. Me SO₂Me CH₂ H Q1a 1621. Me SO₂Me CH₂ H Q1b 1622.Me SO₂Me CH₂ H Q1c 1623. Me SO₂Me CH₂ H Q1d 1624. Me SO₂Me CH₂ H Q1e1625. Me SO₂Me CH₂ H Q2a 1626. Me SO₂Me CH₂ H Q2b 1627. Me SO₂Me CH₂ HQ3a 1628. Me SO₂Me CH₂ H Q3c 1629. Me SO₂Me CH₂ H Q4a 1630. Me SO₂Me CH₂H Q5a 1631. Me SO₂Me CH₂ H Q6a 1632. Me SO₂Me CH₂ H Q8a 1633. Me SO₂MeCH₂ H Q8d 1634. Me SO₂Me CH₂ H Q9a 1635. Me SO₂Me CH₂ H Q12 1636. MeSO₂Me CH₂ H Q13 1637. Me SO₂Me CH₂ Me Q1a 1638. Me SO₂Me CH₂ Me Q2a1639. Me SO₂Me CH₂ Me Q2b 1640. Me SO₂Me CH₂ Me Q3a 1641. Me SO₂Me CH₂Me Q6a 1642. Me SO₂Me CH₂ Me Q8d 1643. Me SO₂Me CH₂ Et Q1a 1644. MeSO₂Me CH₂ n-Pr Q1a 1645. Me SO₂Me CH₂ SMe Q1a 1646. Me SO₂Me CH₂CH₂ HQ1a 1647. Me SO₂Me CH₂CH₂ Me Q1a 1648. Me SO₂Me OCH₂CH₂ H Q1a 1649. MeSO₂Me OCH₂CH₂ H Q1b 1650. Me SO₂Me OCH₂CH₂ H Q1c 1651. Me SO₂Me OCH₂CH₂H Q1d 1652. Me SO₂Me OCH₂CH₂ H Q1e 1653. Me SO₂Me OCH₂CH₂ H Q2a 1654. MeSO₂Me OCH₂CH₂ H Q2b 1655. Me SO₂Me OCH₂CH₂ H Q3a 1656. Me SO₂Me OCH₂CH₂H Q3c 1657. Me SO₂Me OCH₂CH₂ H Q4a 1658. Me SO₂Me OCH₂CH₂ H Q5a 1659. MeSO₂Me OCH₂CH₂ H Q6a 1660. Me SO₂Me OCH₂CH₂ H Q8a 1661. Me SO₂Me OCH₂CH₂H Q8d 1662. Me SO₂Me OCH₂CH₂ H Q9a 1663. Me SO₂Me OCH₂CH₂ H Q12 1664. MeSO₂Me OCH₂CH₂ H Q13 1665. Me SO₂Me OCH₂CH₂ Me Q1a 1666. Me SO₂Me OCH₂CH₂Me Q2a 1667. Me SO₂Me OCH₂CH₂ Me Q2b 1668. Me SO₂Me OCH₂CH₂ Me Q3a 1669.Me SO₂Me OCH₂CH₂ Me Q6a 1670. Me SO₂Me OCH₂CH₂ Me Q8d 1671. Me SO₂MeOCH₂CH₂ Et Q1a 1672. Me SO₂Me OCH₂CH₂ n-Pr Q1a 1673. Me SO₂Me OCH₂CH₂SMe Q1a 1674. Me SO₂Me OCH₂CH(Me) H Q1a 1675. Me SO₂Me OCH₂CH₂CH₂ H Q1a1676. Me SO₂Me OCH₂CH₂CH₂ Me Q1a 1677. Me NO₂ OCH₂CH₂ H Q1a 1678. Me NO₂OCH₂CH₂ H Q1b 1679. Me NO₂ OCH₂CH₂ H Q1c 1680. Me NO₂ OCH₂CH₂ H Q1d1681. Me NO₂ OCH₂CH₂ H Q1e 1682. Me NO₂ OCH₂CH₂ H Q2a 1683. Me NO₂OCH₂CH₂ H Q2b 1684. Me NO₂ OCH₂CH₂ H Q3a 1685. Me NO₂ OCH₂CH₂ H Q3c1686. Me NO₂ OCH₂CH₂ H Q4a 1687. Me NO₂ OCH₂CH₂ H Q5a 1688. Me NO₂OCH₂CH₂ H Q6a 1689. Me NO₂ OCH₂CH₂ H Q8a 1690. Me NO₂ OCH₂CH₂ H Q8d1691. Me NO₂ OCH₂CH₂ H Q9a 1692. Me NO₂ OCH₂CH₂ H Q12 1693. Me NO₂OCH₂CH₂ H Q13 1694. Me NO₂ OCH₂CH₂ Me Q1a 1695. Me NO₂ OCH₂CH₂ Me Q2a1696. Me NO₂ OCH₂CH₂ Me Q2b 1697. Me NO₂ OCH₂CH₂ Me Q3a 1698. Me NO₂OCH₂CH₂ Me Q6a 1699. Me NO₂ OCH₂CH₂ Me Q8d 1700. Me NO₂ OCH₂CH₂ Et Q1a1701. Me NO₂ OCH₂CH₂ n-Pr Q1a 1702. Me NO₂ OCH₂CH₂ SMe Q1a 1703. Me NO₂OCH₂CH(Me) H Q1a 1704. Me NO₂ OCH₂CH₂CH₂ H Q1a 1705. Me NO₂ OCH₂CH₂CH₂Me Q1a 1706. OMe Cl CH₂ H Q1a 1707. OMe Cl CH₂ H Q3a 1708. OMe Cl CH₂ HQ8d 1709. OMe Cl CH₂ Me Q1a 1710. OMe Cl CH₂ Me Q3a 1711. OMe Cl CH₂ MeQ8d 1712. SMe Cl OCH₂CH₂ H Q1a 1713. SMe Cl OCH₂CH₂ H Q3a 1714. SMe ClOCH₂CH₂ H Q8d 1715. SMe Cl OCH₂CH₂ Me Q1a 1716. SMe Cl OCH₂CH₂ Me Q3a1717. SMe Cl OCH₂CH₂ Me Q8d 1718. SMe SMe CH₂ H Q1a 1719. SMe SMe CH₂ HQ3a 1720. SO₂Me Cl OCH₂CH₂ H Q1a 1721. SO₂Me Cl OCH₂CH₂ H Q3a 1722.SO₂Me Cl OCH₂CH₂ H Q8d 1723. SO₂Me Cl OCH₂CH₂ Me Q1a 1724. SO₂Me ClOCH₂CH₂ Me Q3a 1725. SO₂Me Cl OCH₂CH₂ Me Q8d 1726. NO₂ Me OCH₂CH₂ H Q1a1727. NO₂ Me OCH₂CH₂ H Q3a 1728. NO₂ Me OCH₂CH₂ H Q8d 1729. NO₂ MeOCH₂CH₂ Me Q1a 1730. NO₂ Me OCH₂CH₂ Me Q3a 1731. NO₂ Me OCH₂CH₂ Me Q8d1732. NO₂ CH₂OMe OCH₂CH₂ H Q1a 1733. NO₂ CH₂SMe OCH₂CH₂ H Q1a 1734. NO₂CH₂SO₂Me OCH₂CH₂ H Q1a 1735. CN Me OCH₂CH₂ H Q1a 1736. CN Me OCH₂CH₂ HQ3a 1737. CN Me OCH₂CH₂ H Q8d 1738. CN Me OCH₂CH₂ Me Q1a 1739. CN MeOCH₂CH₂ Me Q3a 1740. CN Me OCH₂CH₂ Me Q8d 1741. Cl Cl CH₂ H Q4e 1742. ClCl CH₂ H Q4f 1743. Cl Cl CH₂ H Q4g 1744. Cl Cl CH₂ H Q10b 1745. Cl ClCH₂ H Q16 1746. Cl Cl CH₂ H Q22 1747. Cl Cl OCH₂CH₂ H Q4e 1748. Cl ClOCH₂CH₂ H Q4f 1749. Cl Cl OCH₂CH₂ H Q4g 1750. Cl Cl OCH₂CH₂ H Q4h 1751.Cl Cl OCH₂CH₂ H Q4i 1752. Cl Cl OCH₂CH₂ H Q4j 1753. Cl Cl OCH₂CH₂ H Q10b1754. Cl Cl OCH₂CH₂ H Q10c 1755. Cl Cl OCH₂CH₂ H Q10d 1756. Cl ClOCH₂CH₂ H Q10c 1757. Cl Cl OCH₂CH₂ H Q10f 1758. Cl Cl OCH₂CH₂ H Q161759. Cl Cl OCH₂CH₂ H Q17 1760. Cl Cl OCH₂CH₂ H Q18 1761. Cl Cl OCH₂CH₂H Q19 1762. Cl Cl OCH₂CH₂ H Q20 1763. Cl Cl OCH₂CH₂ H Q21 1764. Cl ClOCH₂CH₂ H Q22 1765. Cl Cl OCH₂CH₂ H Q23 1766. Cl Cl OCH₂CH₂ H Q24 1767.Cl Cl OCH₂CH₂ H Q25 1768. Cl Cl OCH₂CH₂ H Q26 1769. Cl Cl OCH₂CH₂ Me Q4e1770. Cl Cl OCH₂CH₂ Me Q4f 1771. Cl Cl OCH₂CH₂ Me Q10b 1772. Cl ClOCH₂CH₂ Me Q16 1773. Cl Cl OCH₂CH₂ Me Q19 1774. Cl Cl OCH₂CH₂ Me Q221775. Cl SO₂Me CH₂ H Q4e 1776. Cl SO₂Me CH₂ H Q4f 1777. Cl SO₂Me CH₂ HQ4g 1778. Cl SO₂Me CH₂ H Q4h 1779. Cl SO₂Me CH₂ H Q4i 1780. Cl SO₂Me CH₂H Q4j 1781. Cl SO₂Me CH₂ H Q10b 1782. Cl SO₂Me CH₂ H Q10c 1783. Cl SO₂MeCH₂ H Q10d 1784. Cl SO₂Me CH₂ H Q10e 1785. Cl SO₂Me CH₂ H Q10f 1786. ClSO₂Me CH₂ H Q11b 1787. Cl SO₂Me CH₂ H Q11c 1788. Cl SO₂Me CH₂ H Q1ld1789. Cl SO₂Me CH₂ H Q16 1790. Cl SO₂Me CH₂ H Q17 1791. Cl SO₂Me CH₂ HQ18 1792. Cl SO₂Me CH₂ H Q19 1793. Cl SO₂Me CH₂ H Q20 1794. Cl SO₂Me CH₂H Q21 1795. Cl SO₂Me CH₂ H Q22 1796. Cl SO₂Me CH₂ H Q23 1797. Cl SO₂MeCH₂ H Q24 1798. Cl SO₂Me CH₂ H Q25 1799. Cl SO₂Me CH₂ H Q26 1800. ClSO₂Me CH₂ Me Q4e 1801. Cl SO₂Me CH₂ Me Q4f 1802. Cl SO₂Me CH₂ Me Q10b1803. Cl SO₂Me CH₂ Me Q16 1804. Cl SO₂Me CH₂ Me Q19 1805. Cl SO₂Me CH₂Me Q22*Substituent R^(1c) is mentioned in parenthesis in the column of thegroup R^(1b), only when it is other than a hydrogen atom (H).

TABLE 2 Compound Mp (° C.) No. R^(1a) R^(1b) (R^(1c)) (O)_(n)—A R² Q orn_(D) ²⁰ 1806. H Cl OCH₂CH₂ H Q1a 1807. H Cl OCH₂CH₂ H Q2a 1808. F ClCH₂ H Q1a 1809. F Cl OCH₂CH₂ H Q1a 1810. F Cl CH₂ Me Q1a 1811. Cl F CH₂H Q1a 1812. Cl F CH₂ Me Q1a 1813. Cl F OCH₂CH₂ H Q1a 1814. Cl F OCH₂CH₂H Q1b 1815. Cl F OCH₂CH₂ H Q1c 1816. Cl F OCH₂CH₂ H Q1d 1817. Cl FOCH₂CH₂ H Q1e 1818. Cl F OCH₂CH₂ H Q2a 1819. Cl F OCH₂CH₂ H Q2b 1820. ClF OCH₂CH₂ H Q3a 1821. Cl F OCH₂CH₂ H Q3c 1822. Cl F OCH₂CH₂ H Q4a 1823.Cl F OCH₂CH₂ H QSa 1824. Cl F OCH₂CH₂ H Q6a 1825. Cl F OCH₂CH₂ H Q8a1826. Cl F OCH₂CH₂ H Q8d 1827. Cl F OCH₂CH₂ H Q9a 1828. Cl F OCH₂CH₂ HQ12 1829. Cl F OCH₂CH₂ H Q13 1830. Cl F OCH₂CH₂ Me Q1a 1831. Cl FOCH₂CH₂ Me Q2a 1832. Cl F OCH₂CH₂ Me Q2b 1833. Cl F OCH₂CH₂ Me Q3a 1834.Cl F OCH₂CH₂ Me Q6a 1835. Cl F OCH₂CH₂ Me Q8d 1836. Cl F OCH₂CH(Me) HQ1a 1837. Cl F OCH₂CH₂CH₂ H Q1a 1838. Cl Cl CH₂ H Q1a 113-114 1839. ClCl CH₂ H Q1b 1840. Cl Cl CH₂ H Q1c 1841. Cl Cl CH₂ H Q1d 1842. Cl Cl CH₂H Q1e 1843. Cl Cl CH₂ H Q2a 1844. Cl Cl CH₂ H Q2b 1845. Cl Cl CH₂ H Q3a146-147 1846. Cl Cl CH₂ H Q3b 1847. Cl Cl CH₂ H Q3c 1848. Cl Cl CH₂ HQ3d 1849. Cl Cl CH₂ H Q3e 1850. Cl Cl CH₂ H Q3f 1851. Cl Cl CH₂ H Q3g1852. Cl Cl CH₂ H Q3h 1853. Cl Cl CH₂ H Q3i 1854. Cl Cl CH₂ H Q3j 1855.Cl Cl CH₂ H Q3k 1856. Cl Cl CH₂ H Q31 1857. Cl Cl CH₂ H Q3m 1858. Cl ClCH₂ H Q3n 1859. Cl Cl CH₂ H Q3o 1860. Cl Cl CH₂ H Q3p 1861. Cl Cl CH₂ HQ3q 1862. Cl Cl CH₂ H Q3r 1863. Cl Cl CH₂ H Q3s 1864. Cl Cl CH₂ H Q3t1865. Cl Cl CH₂ H Q3u 1866. Cl Cl CH₂ H Q3v 1867. Cl Cl CH₂ H Q3w 1868.Cl Cl CH₂ H Q3x 1869. Cl Cl CH₂ H Q3y 1870. Cl Cl CH₂ H Q3z 1871. Cl ClCH₂ H Q3za 1872. Cl Cl CH₂ H Q3zb 1873. Cl Cl CH₂ H Q3zc 1874. Cl Cl CH₂H Q3zd 1875. Cl Cl CH₂ H Q4a 1876. Cl Cl CH₂ H Q4b 1877. Cl Cl CH₂ H Q4c1878. Cl Cl CH₂ H Q4d 1879. Cl Cl CH₂ H Q5a 1880. Cl Cl CH₂ H Q5b 1881.Cl Cl CH₂ H Q5c 1882. Cl Cl CH₂ H Q6a 1883. Cl Cl CH₂ H Q6b 1884. Cl ClCH₂ H Q7 1885. Cl Cl CH₂ H Q8a 1886. Cl Cl CH₂ H Q8b 1887. Cl Cl CH₂ HQ8c 1888. Cl Cl CH₂ H Q8d 1889. Cl Cl CH₂ H Q9a 1890. Cl Cl CH₂ H Q9b1891. Cl Cl CH₂ H Q9c 1892. Cl Cl CH₂ H Q9d 1893. Cl Cl CH₂ H Q10a 1894.Cl Cl CH₂ H Q11a 1895. Cl Cl CH₂ H Q12 1896. Cl Cl CH₂ H Q13 1897. Cl ClCH₂ H Q14 1898. Cl Cl CH₂ H Q15 1899. Cl Cl CH₂ Me Q1a 1900. Cl Cl CH₂Me Q1b 1901. Cl Cl CH₂ Me Q1c 1902. Cl Cl CH₂ Me Q1d 1903. Cl Cl CH₂ MeQ1e 1904. Cl Cl CH₂ Me Q2a 1905. Cl Cl CH₂ Me Q2b 1906. Cl Cl CH₂ Me Q3a1907. Cl Cl CH₂ Me Q3b 1908. Cl Cl CH₂ Me Q3c 1909. Cl Cl CH₂ Me Q3d1910. Cl Cl CH₂ Me Q3e 1911. Cl Cl CH₂ Me Q3f 1912. Cl Cl CH₂ Me Q3g1913. Cl Cl CH₂ Me Q3h 1914. Cl Cl CH₂ Me Q3i 1915. Cl Cl CH₂ Me Q3j1916. Cl Cl CH₂ Me Q3k 1917. Cl Cl CH₂ Me Q31 1918. Cl Cl CH₂ Me Q3m1919. Cl Cl CH₂ Me Q3n 1920. Cl Cl CH₂ Me Q3o 1921. Cl Cl CH₂ Me Q3p1922. Cl Cl CH₂ Me Q3q 1923. Cl Cl CH₂ Me Q3r 1924. Cl Cl GB2 Me Q3s1925. Cl Cl GB2 Me Q3t 1926. Cl Cl GB2 Me Q3u 1927. Cl Cl GB2 Me Q3v1928. Cl Cl GB2 Me Q3w 1929. Cl Cl CH₂ Me Q3x 1930. Cl Cl GB2 Me Q3y1931. Cl Cl CH₂ Me Q3z 1932. Cl Cl CH₂ Me Q3za 1933. Cl Cl GB2 Me Q3zb1934. Cl Cl CH₂ Me Q3zc 1935. Cl Cl CH₂ Me Q3zd 1936. Cl Cl CH₂ Me Q4a1937. Cl Cl CH₂ Me Q4b 1938. Cl Cl CH₂ Me Q4c 1939. Cl Cl CH₂ Me Q4d1940. Cl Cl CH₂ Me Q5a 1941. Cl Cl CH₂ Me Q6a 1942. Cl Cl CH₂ Me Q6b1943. Cl Cl CH₂ Me Q7 1944. Cl Cl CH₂ Me Q8a 1945. Cl Cl CH₂ Me Q8b1946. Cl Cl CH₂ Me Q8c 1947. Cl Cl CH₂ Me Q8d 1948. Cl Cl CH₂ Me Q9a1949. Cl Cl CH₂ Me Q9b 1950. Cl Cl CH₂ Me Q9c 1951. Cl Cl CH₂ Me Q9d1952. Cl Cl CH₂ Me Q10a 1953. Cl Cl CH₂ Me Q11a 1954. Cl Cl CH₂ Me Q121955. Cl Cl CH₂ Me Q13 1956. Cl Cl CH₂ Me Q14 1957. Cl Cl CH₂ Me Q151958. Cl Cl CH₂ Et Q1a 1959. Cl Cl CH₂ Et Q1b 1960. Cl Cl CH₂ Et Q1c1961. Cl Cl CH₂ Et Q1d 1962. Cl Cl CH₂ Et Q1e 1963. Cl Cl CH₂ Et Q2a1964. Cl Cl CH₂ Et Q2b 1965. Cl Cl CH₂ Et Q3a 1966. Cl Cl CH₂ Et Q3c1967. Cl Cl CH₂ Et Q4a 1968. Cl Cl CH₂ Et Q5a 1969. Cl Cl CH₂ Et Q6a1970. Cl Cl CH₂ Et Q8a 1971. Cl Cl CH₂ Et Q8d 1972. Cl Cl CH₂ Et Q9a1973. Cl Cl CH₂ Et Q12 1974. Cl Cl CH₂ Et Q13 1975. Cl Cl CH₂ n-Pr Q1a1976. Cl Cl CH₂ n-Pr Q3a 1977. Cl Cl CH₂ n-Pr Q6a 1978. Cl Cl CH₂ SMeQ1a 106-109 1979. Cl Cl CH₂ SMe Q1b 1980. Cl Cl CH₂ SMe Q1c 1981. Cl ClCH₂ SMe Q1d 1982. Cl Cl CH₂ SMe Q1e 1983. Cl Cl CH₂ SMe Q2a 1984. Cl ClCH₂ SMe Q2b 1985. GI Cl CH₂ SMe Q3a 1986. Cl Cl CH₂ SMe Q3c 1987. Cl ClCH₂ SMe Q4a 1988. Cl Cl CH₂ SMe Q5a 1989. Cl Cl CH₂ SMe Q6a 1990. Cl ClCH₂ SMe Q8a 1991. Cl Cl CH₂ SMe Q8d 1992. Cl Cl CH₂ SMe Q9a 1993. Cl ClCH₂ SMe Q12 1994. Cl Cl CH₂ SMe Q13 1995. Cl Cl CH₂CH₂ H Q1a 1996. Cl ClCH₂CH₂ H Q1b 1997. Cl Cl CH₂CH₂ H Q1c 1998. Cl Cl CH₂CH₂ H Q1d 1999. ClCl CH₂CH₂ H Q1e 2000. Cl Cl CH₂CH₂ H Q2a 2001. Cl Cl CH₂CH₂ H Q2b 2002.Cl Cl CH₂CH₂ H Q3a 2003. Cl Cl CH₂CH₂ H Q3c 2004. Cl Cl CH₂CH₂ H Q4a2005. Cl Cl CH₂CH₂ H Q5a 2006. Cl Cl CH₂CH₂ H Q6a 2007. Cl Cl CH₂CH₂ HQ8a 2008. Cl Cl CH₂CH₂ H Q8d 2009. Cl Cl CH₂CH₂ H Q9a 2010. Cl Cl CH₂CH₂H Q12 2011. Cl Cl CH₂CH₂ H Q13 2012. Cl Cl CH₂CH₂ Me Q1a 2013. Cl ClCH₂CH₂ Me Q2a 2014. Cl Cl CH₂CH₂ Me Q2b 2015. Cl Cl CH₂CH₂ Me Q3a 2016.Cl Cl CH₂CH₂ Me Q6a 2017. Cl Cl OCH₂CH₂ H Q1a 1.5892 2018. Cl Cl OCH₂CH₂H Q1b 1.5725 2019. Cl Cl OCH₂CH₂ H Q1c 2020. Cl Cl OCH₂CH₂ H Q1d 1.57352021. Cl Cl OCH₂CH₂ H Q1e 2022. Cl Cl OCH₂CH₂ H Q2a 1.5860 2023. Cl ClOCH₂CH₂ H Q2b 1.5779 2024. Cl Cl OCH₂CH₂ H Q3a 1.6290 2025. Cl ClOCH₂CH₂ H Q3b 2026. Cl Cl OCH₂CH₂ H Q3c 2027. Cl Cl OCH₂CH₂ H Q3d 2028.Cl Cl OCH₂CH₂ H Q3e 2029. Cl Cl OCH₂CH₂ H Q3f 2030. Cl Cl OCH₂CH₂ H Q3g2031. Cl Cl OCH₂CH₂ H Q3h 2032. Cl Cl OCH₂CH₂ H Q3i 2033. Cl Cl OCH₂CH₂H Q3j 2034. Cl Cl OCH₂CH₂ H Q3k 2035. Cl Cl OCH₂CH₂ H Q31 2036. Cl ClOCH₂CH₂ H Q3m 2037. Cl Cl OCH₂CH₂ H Q3n 2038. Cl Cl OCH₂CH₂ H Q3o 2039.Cl Cl OCH₂CH₂ H Q3p 2040. Cl Cl OCH₂CH₂ H Q3q 2041. Cl Cl OCH₂CH₂ H Q3r2042. Cl Cl OCH₂CH₂ H Q3s 2043. Cl Cl OCH₂CH₂ H Q3t 2044. Cl Cl OCH₂CH₂H Q3u 2045. Cl Cl OCH₂CH₂ H Q3v 2046. Cl Cl OCH₂CH₂ H Q3w 2047. Cl ClOCH₂CH₂ H Q3x 2048. Cl Cl OCH₂CH₂ H Q3y 2049. Cl Cl OCH₂CH₂ H Q3z 2050.Cl Cl OCH₂CH₂ H Q3za 2051. Cl Cl OCH₂CH₂ H Q3zb 2052. Cl Cl OCH₂CH₂ HQ3zc 2053. Cl Cl OCH₂CH₂ H Q3zd 2054. Cl Cl OCH₂CH₂ H Q4a 2055. Cl ClOCH₂CH₂ H Q4b 2056. Cl Cl OCH₂CH₂ H Q4c 2057. Cl Cl OCH₂CH₂ H Q4d 2058.Cl Cl OCH₂CH₂ H Q5a 2059. Cl Cl OCH₂CH₂ H Q5b 2060. Cl Cl OCH₂CH₂ H Q5c2061. Cl Cl OCH₂CH₂ H Q5d 2062. Cl Cl OCH₂CH₂ H Q5e 2063. Cl Cl OCH₂CH₂H Q6a 1.5783 2064. Cl Cl OCH₂CH₂ H Q6b 2065. Cl Cl OCH₂CH₂ H Q7 2066. ClCl OCH₂CH₂ H Q8a 2067. Cl Cl OCH₂CH₂ H Q8b 2068. Cl Cl OCH₂CH₂ H Q8c2069. Cl Cl OCH₂CH₂ H Q8d 2070. Cl Cl OCH₂CH₂ H Q9a 2071. Cl Cl OCH₂CH₂H Q9b 2072. Cl Cl OCH₂CH₂ H Q9c 2073. Cl Cl OCH₂CH₂ H Q9d 2074. Cl ClOCH₂CH₂ H Q10a 2075. Cl Cl OCH₂CH₂ H Q11a 2076. Cl Cl OCH₂CH₂ H Q122077. Cl Cl OCH₂CH₂ H Q13 1.5620 2078. Cl Cl OCH₂CH₂ H Q14 2079. Cl ClOCH₂CH₂ H Q15 2080. Cl Cl OCH₂CH₂ Me Q1a 1.5839 2081. Cl Cl OCH₂CH₂ MeQ1b 1.5560 2082. Cl Cl OCH₂CH₂ Me Q1c 2083. Cl Cl OCH₂CH₂ Me Q1d 1.56372084. Cl Cl OCH₂CH₂ Me Q1e 2085. Cl Cl OCH₂CH₂ Me Q2a 2086. Cl ClOCH₂CH₂ Me Q2b 2087. Cl Cl OCH₂CH₂ Me Q3a 2088. Cl Cl OCH₂CH₂ Me Q3b2089. Cl Cl OCH₂CH₂ Me Q3c 2090. Cl Cl OCH₂CH₂ Me Q3d 2091. Cl ClOCH₂CH₂ Me Q3e 2092. Cl Cl OCH₂CH₂ Me Q3f 2093. Cl Cl OCH₂CH₂ Me Q3g2094. Cl Cl OCH₂CH₂ Me Q3h 2095. Cl Cl OCH₂CH₂ Me Q3i 2096. Cl ClOCH₂CH₂ Me Q3j 2097. Cl Cl OCH₂CH₂ Me Q3k 2098. Cl Cl OCH₂CH₂ Me Q312099. Cl Cl OCH₂CH₂ Me Q3m 2100. Cl Cl OCH₂CH₂ Me Q3n 2101. Cl ClOCH₂CH₂ Me Q3o 2102. Cl Cl OCH₂CH₂ Me Q3p 2103. Cl Cl OCH₂CH₂ Me Q3q2104. Cl Cl OCH₂CH₂ Me Q3r 2105. Cl Cl OCH₂CH₂ Me Q3s 2106. Cl ClOCH₂CH₂ Me Q3t 2107. Cl Cl OCH₂CH₂ Me Q3u 2108. Cl Cl OCH₂CH₂ Me Q3v2109. Cl Cl OCH₂CH₂ Me Q3w 2110. Cl Cl OCH₂CH₂ Me Q3x 2111. Cl ClOCH₂CH₂ Me Q3y 2112. Cl Cl OCH₂CH₂ Me Q3z 2113. Cl Cl OCH₂CH₂ Me Q3za2114. Cl Cl OCH₂CH₂ Me Q3zb 2115. Cl Cl OCH₂CH₂ Me Q3zc 2116. Cl ClOCH₂CH₂ Me Q3zd 2117. Cl Cl OCH₂CH₂ Me Q4a 2118. Cl Cl OCH₂CH₂ Me Q4b2119. Cl Cl OCH₂CH₂ Me Q4c 2120. Cl Cl OCH₂CH₂ Me Q4d 2121. Cl ClOCH₂CH₂ Me Q5a 2122. Cl Cl OCH₂CH₂ Me Q5b 2123. Cl Cl OCH₂CH₂ Me Q5c2124. Cl Cl OCH₂CH₂ Me Q6a 2125. Cl Cl OCH₂CH₂ Me Q6b 2126. Cl ClOCH₂CH₂ Me Q7 2127. Cl Cl OCH₂CH₂ Me Q8a 2128. Cl Cl OCH₂CH₂ Me Q8b2129. Cl Cl OCH₂CH₂ Me Q8c 2130. Cl Cl OCH₂CH₂ Me Q8d 2131. Cl ClOCH₂CH₂ Me Q9a 2132. Cl Cl OCH₂CH₂ Me Q9b 2133. Cl Cl OCH₂CH₂ Me Q9c2134. Cl Cl OCH₂CH₂ Me Q9d 2135. Cl Cl OCH₂CH₂ Me Q10a 2136. Cl ClOCH₂CH₂ Me Q11a 2137. Cl Cl OCH₂CH₂ Me Q12 2138. Cl Cl OCH₂CH₂ Me Q132139. Cl Cl OCH₂CH₂ Me Q14 2140. Cl Cl OCH₂CH₂ Me Q15 2141. Cl ClOCH₂CH₂ Et Q1a 2142. Cl Cl OCH₂CH₂ Et Q1b 2143. Cl Cl OCH₂CH₂ Et Q1c2144. Cl Cl OCH₂CH₂ Et Q1d 2145. Cl Cl OCH₂CH₂ Et Q1e 2146. Cl ClOCH₂CH₂ Et Q2a 2147. Cl Cl OCH₂CH₂ Et Q2b 2148. Cl Cl OCH₂CH₂ Et Q3a2149. Cl Cl OCH₂CH₂ Et Q3c 2150. Cl Cl OCH₂CH₂ Et Q4a 2151. Cl ClOCH₂CH₂ Et Q5a 2152. Cl Cl OCH₂CH₂ Et Q6a 2153. Cl Cl OCH₂CH₂ Et Q8a2154. Cl Cl OCH₂CH₂ Et Q8d 2155. Cl Cl OCH₂CH₂ Et Q9a 2156. Cl ClOCH₂CH₂ Et Q12 2157. Cl Cl OCH₂CH₂ Et Q13 2158. Cl Cl OCH₂CH₂ n-Pr Q1a2159. Cl Cl OCH₂CH₂ n-Pr Q3a 2160. Cl Cl OCH₂CH₂ n-Pr Q6a 2161. Cl ClOCH₂CH₂ SMe Q1a 2162. Cl Cl OCH₂CH₂ SMe Q3a 2163. Cl Cl OCH₂CH₂ SMe Q6a2164. Cl Cl OCH₂CH(Me) H Q1a 2165. Cl Cl OCH₂CH(Me) H Q1b 2166. Cl ClOCH₂CH(Me) H Q1c 2167. Cl Cl OCH₂CH(Me) H Q1d 2168. Cl Cl OCH₂CH(Me) HQ1e 2169. Cl Cl OCH₂CH(Me) H Q2a 2170. Cl Cl OCH₂CH(Me) H Q2b 2171. ClCl OCH₂CH(Me) H Q3a 2172. Cl Cl OCH₂CH(Me) H Q3c 2173. Cl Cl OCH₂CH(Me)H Q4a 2174. Cl Cl OCH₂CH(Me) H Q5a 2175. Cl Cl OCH₂CH(Me) H Q6a 2176. ClCl OCH₂CH(Me) H Q8a 2177. Cl Cl OCH₂CH(Me) H Q8d 2178. Cl Cl OCH₂CH(Me)H Q9a 2179. Cl Cl OCH₂CH(Me) H Q12 2180. Cl Cl OCH₂CH(Me) H Q13 2181. ClCl OCH₂CH(Me) Me Q1a 2182. Cl Cl OCH₂CH(Me) Me Q3a 2183. Cl ClOCH₂CH(Me) Me Q6a 2184. Cl Cl OCH₂CH₂CH₂ H Q1a 2185. Cl Cl OCH₂CH₂CH₂ HQ1b 2186. Cl Cl OCH₂CH₂CH₂ H Q1c 2187. Cl Cl OCH₂CH₂CH₂ H Q1d 2188. ClCl OCH₂CH₂CH₂ H Q1e 2189. Cl Cl OCH₂CH₂CH₂ H Q2a 2190. Cl Cl OCH₂CH₂CH₂H Q2b 2191. Cl Cl OCH₂CH₂CH₂ H Q3a 2192. Cl Cl OCH₂CH₂CH₂ H Q3c 2193. ClCl OCH₂CH₂CH₂ H Q4a 2194. Cl Cl OCH₂CH₂CH₂ H Q5a 2195. Cl Cl OCH₂CH₂CH₂H Q6a 2196. Cl Cl OCH₂CH₂CH₂ H Q8a 2197. Cl Cl OCH₂CH₂CH₂ H Q8d 2198. ClCl OCH₂CH₂CH₂ H Q9a 2199. Cl Cl OCH₂CH₂CH₂ H Q12 2200. Cl Cl OCH₂CH₂CH₂H Q13 2201. Cl Cl OCH₂CH₂CH₂ Me Q1a 2202. Cl Cl OCH₂CH₂CH₂ Me Q3a 2203.Cl Cl OCH₂CH₂CH₂ Me Q6a 2204. Cl Cl CH(Me) H Q1a 2205. Cl Cl CH(Me)CH₂ HQ1a 2206. Cl Cl CH₂CH₂CH₂ H Q1a 2207. Cl Cl OCH₂ H Q1a 2208. Cl ClOCH(Me)CH₂ H Q1a 2209. Cl Cl(Me) OCH₂CH₂ H Q1a 2210. Cl Cl(Me) OCH₂CH₂ HQ2a 2211. Cl Cl(Me) OCH₂CH₂ H Q2b 2212. Cl Cl(Me) OCH₂CH₂ H Q3a 2213. ClCl(Me) OCH₂CH₂ H Q6a 2214. Cl Cl(Me) OCH₂CH₂ H Q8d 2215. Cl C1(Me)OCH₂CH₂ Me Q1a 2216. Cl Cl(Me) OC.H₂CH₂ Me Q2a 2217. Cl Cl(Me) OCH₂CH₂Me Q2b 2218. Cl Cl(Me) OCH₂CH₂ Me Q3a 2219. Cl Cl(Me) OCH₂CH₂ Me Q6a2220. Cl Cl(Me) OCH₂CH₂ Me Q8d 2221. Cl Br CH₂ H Q1a 2222. Cl Br CH₂ MeQ1a 2223. Cl Br OCH₂CH₂ H Q1a 2224. Cl Br OCH₂CH₂ H Q1b 2225. Cl BrOCH₂CH₂ H Q1c 2226. Cl Br OCH₂CH₂ H Q1d 2227. Cl Br OCH₂CH₂ H Q1e 2228.Cl Br OCH₂CH₂ H Q2a 2229. Cl Br OCH₂CH₂ H Q2b 2230. Cl Br OCH₂CH₂ H Q3a2231. Cl Br OCH₂CH₂ H Q3c 2232. Cl Br OCH₂CH₂ H Q4a 2233. Cl Br OCH₂CH₂H Q5a 2234. Cl Br OCH₂CH₂ H Q6a 2235. Cl Br OCH₂CH₂ H Q8a 2236. Cl BrOCH₂CH₂ H Q8d 2237. Cl Br OCH₂CH₂ H Q9a 2238. Cl Br OCH₂CH₂ H Q12 2239.Cl Br OCH₂CH₂ H Q13 2240. Cl Br OCH₂CH₂ Me Q1a 2241. Cl Br OCH₂CH₂ MeQ3a 2242. Cl Br OCH₂CH₂ Me Q6a 2243. Cl Br OCH₂CH(Me) H Q1a 2244. Cl BrOCH₂CH₂CH₂ H Q1a 2245. Cl I OCH₂CH₂ H Q1a 2246. Cl I OCH₂CH₂ Me Q1a2247. Cl Me OCH₂CH₂ H Q1a 2248. Cl Me OCH₂CH₂ H Q1b 2249. Cl Me OCH₂CH₂H Q1c 2250. Cl Me OCH₂CH₂ H Q1d 2251. Cl Me OCH₂CH₂ H Q1e 2252. Cl MeOCH₂CH₂ H Q2a 2253. Cl Me OCH₂CH₂ H Q2b 2254. Cl Me OCH₂CH₂ H Q3a 2255.Cl Me OCH₂CH₂ H Q3c 2256. Cl Me OCH₂CH₂ H Q4a 2257. Cl Me OCH₂CH₂ H Q5a2258. Cl Me OCH₂CH₂ H Q6a 2259. Cl Me OCH₂CH₂ H Q8a 2260. Cl Me OCH₂CH₂H Q8d 2261. Cl Me OCH₂CH₂ H Q9a 2262. Cl Me OCH₂CH₂ H Q12 2263. Cl MeOCH₂CH₂ H Q13 2264. Cl Me OCH₂CH₂ Me Q1a 2265. Cl Me OCH₂CH₂ Me Q2a2266. Cl Me OCH₂CH₂ Me Q2b 2267. Cl Me OCH₂CH₂ Me Q3a 2268. Cl MeOCH₂CH₂ Me Q6a 2269. Cl Me OCH₂CH₂ Me Q8d 2270. Cl Me OCH₂CH(Me) H Q1a2271. Cl Me OCH₂CH₂CH₂ H Q1a 2272. Cl CF3 OCH₂CH₂ H Q1a 2273. Cl CF3OCH₂CH₂ H Q2a 2274. Cl CF3 OCH₂CH₂ H Q2b 2275. Cl CF3 OCH₂CH₂ H Q3a2276. Cl CF3 OCH₂CH₂ Me Q1a 2277. Cl CF3 OCH₂CH₂ Me Q3a 2278. Cl CF3OCH₂CH₂CH₂ H Q1a 2279. Cl CF3 OCH₂CH₂CH₂ Me Q1a 2280. Cl OMe CH₂ H Q1a114-116 2281. Cl OMe CH₂ H Q3a 2282. Cl OMe CH₂ Me Q1a 2283. Cl OSO₂MeCH₂ H Q1a 2284. Cl OSO₂Et CH₂ H Q1a 2285. Cl SMe CH₂ H Q1a 2286. Cl SMeCH₂ H Q3a 2287. Cl SMe CH₂ Me Q1a 2288. Cl SMe OCH₂CH₂ H Q1a 2289. ClSMe OCH₂CH₂ H Q2a 2290. Cl SMe OCH₂CH₂ H Q2b 2291. Cl SMe OCH₂CH₂ H Q3a2292. Cl SMe OCH₂CH₂ H Q6a 2293. Cl SMe OCH₂CH₂ H Q8d 2294. Cl SMeOCH₂CH₂ Me Q1a 2295. Cl SMe OCH₂CH₂ Me Q3a 2296. Cl SMe OCH₂CH(Me) H Q1a2297. Cl SMe OCH₂CH₂CH₂ H Q1a 2298. Cl SEt CH₂ H Q1a 2299. Cl SEtOCH₂CH₂ H Q1a 2300. Cl SEt OCH₂CH₂ Me Q1a 2301. Cl SO₂Me CH₂ H Q1a194-197 2302. Cl SO₂Me CH₂ H Q1b 2303. Cl SO₂Me CH₂ H Q1c 2304. Cl SO₂MeCH₂ H Q1d 2305. Cl SO₂Me CH₂ H Q1e 2306. Cl SO₂Me CH₂ H Q2a 2307. ClSO₂Me CH₂ H Q2b 2308. Cl SO₂Me CH₂ H Q3a 93-97 2309. Cl SO₂Me CH₂ H Q3b2310. Cl SO₂Me CH₂ H Q3c 182-183 2311. Cl SO₂Me CH₂ H Q3d 2312. Cl SO₂MeCH₂ H Q3e 165-167 2313. Cl SO₂Me CH₂ H Q3f 2314. Cl SO₂Me CH₂ H Q3g2315. Cl SO₂Me CH₂ H Q3h 2316. Cl SO₂Me CH₂ H Q3i 2317. Cl SO₂Me CH₂ HQ3j 2318. Cl SO₂Me CH₂ H Q3k 2319. Cl SO₂Me CH₂ H Q31 2320. Cl SO₂Me CH₂H Q3m 2321. Cl SO₂Me CH₂ H Q3n 2322. Cl SO₂Me CH₂ H Q3o 2323. Cl SO₂MeCH₂ H Q3p 2324. Cl SO₂Me CH₂ H Q3q 2325. Cl SO₂Me CH₂ H Q3r 2326. ClSO₂Me CH₂ H Q3s 2327. Cl SO₂Me CH₂ H Q3t 222-227 2328. Cl SO₂Me CH₂ HQ3u 2329. Cl SO₂Me CH₂ H Q3v 172-174 2330. Cl SO₂Me CH₂ H Q3w 2331. ClSO₂Me CH₂ H Q3x 2332. Cl SO₂Me CH₂ H Q3y 2333. Cl SO₂Me CH₂ H Q3z 2334.Cl SO₂Me CH₂ H Q3za 2335. Cl SO₂Me CH₂ H Q3zb 213-214 2336. Cl SO₂Me CH₂H Q3zc 2337. Cl SO₂Me CH₂ H Q3zd 2338. Cl SO₂Me CH₂ H Q4a 146-148 2339.Cl SO₂Me CH₂ H Q4b 2340. Cl SO₂Me CH₂ H Q4c 2341. Cl SO₂Me CH₂ H Q4d2342. Cl SO₂Me CH₂ H Q5a 2343. Cl SO₂Me CH₂ H Q5b 2344. Cl SO₂Me CH₂ HQ5c 2345. Cl SO₂Me CH₂ H Q5d 2346. Cl SO₂Me CH₂ H Q5e 2347. Cl SO₂Me CH₂H Q6a 70-75 2348. Cl SO₂Me CH₂ H Q6b 2349. Cl SO₂Me CH₂ H Q7 2350. ClSO₂Me CH₂ H Q8a 2351. Cl SO₂Me CH₂ H Q8b 2352. Cl SO₂Me CH₂ H Q8c 2353.Cl SO₂Me CH₂ H Q8d 2354. Cl SO₂Me CH₂ H Q9a 2355. Cl SO₂Me CH₂ H Q9b2356. Cl SO₂Me CH₂ H Q9c 2357. Cl SO₂Me CH₂ H Q9d 2358. Cl SO₂Me CH₂ HQ10a 2359. Cl SO₂Me CH₂ H Q11a 2360. Cl SO₂Me GEl2 H Q12 2361. Cl SO₂MeCH₂ H Q13 2362. Cl SO₂Me CH₂ H Q14 2363. Cl SO₂Me CH₂ H Q15 2364. ClSO₂Me CH₂ Me Q1a 63-66 2365. Cl SO₂Me CH₂ Me Q1b 2366. Cl SO₂Me CH₂ MeQ1c 2367. Cl SO₂Me CH₂ Me Q1d 2368. Cl SO₂Me CH₂ Me Q1e 2369. Cl SO₂MeCH₂ Me Q2a 2370. Cl SO₂Me CH₂ Me Q2b 2371. Cl SO₂Me CH₂ Me Q3a 2372. ClSO₂Me CH₂ Me Q3b 2373. Cl SO₂Me CH₂ Me Q3c 2374. Cl SO₂Me CH₂ Me Q3d2375. Cl SO₂Me CH₂ Me Q3e 2376. Cl SO₂Me CH₂ Me Q3f 2377. Cl SO₂Me CH₂Me Q3g 2378. Cl SO₂Me CH₂ Me Q3h 2379. Cl SO₂Me CH₂ Me Q3i 2380. ClSO₂Me CH₂ Me Q3j 2381. Cl SO₂Me CH₂ Me Q3k 2382. Cl SO₂Me CH₂ Me Q312383. Cl SO₂Me CH₂ Me Q3m 2384. Cl SO₂Me CH₂ Me Q3n 2385. Cl SO₂Me CH₂Me Q3o 2386. Cl SO₂Me CH₂ Me Q3p 2387. Cl SO₂Me CH₂ Me Q3q 2388. ClSO₂Me CH₂ Me Q3r 2389. Cl SO₂Me CH₂ Me Q3s 2390. Cl SO₂Me CH₂ Me Q3t2391. Cl SO₂Me CH₂ Me Q3u 2392. Cl SO₂Me CH₂ Me Q3v 2393. Cl SO₂Me CH₂Me Q3w 2394. Cl SO₂Me CH₂ Me Q3x 2395. Cl SO₂Me CH₂ Me Q3y 2396. ClSO₂Me CH₂ Me Q3z 2397. Cl SO₂Me CH₂ Me Q3za 2398. Cl SO₂Me CH₂ Me Q3zb2399. Cl SO₂Me CH₂ Me Q3zc 2400. Cl SO₂Me CH₂ Me Q3zd 2401. Cl SO₂Me CH₂Me Q4a 2402. Cl SO₂Me CH₂ Me Q4b 2403. Cl SO₂Me CH₂ Me Q4c 2404. ClSO₂Me CH₂ Me Q4d 2405. Cl SO₂Me CH₂ Me Q5a 2406. Cl SO₂Me CH₂ Me Q5b2407. Cl SO₂Me CH₂ Me Q5c 2408. Cl SO₂Me CH₂ Me Q6a 2409. Cl SO₂Me CH₂Me Q6b 2410. Cl SO₂Me CH₂ Me Q7 2411. Cl SO₂Me CH₂ Me Q8a 2412. Cl SO₂MeCH₂ Me Q8b 2413. Cl SO₂Me CH₂ Me Q8c 2414. Cl SO₂Me CH₂ Me Q8d 2415. ClSO₂Me CH₂ Me Q9a 2416. Cl SO₂Me CH₂ Me Q9b 2417. Cl SO₂Me CH₂ Me Q9c2418. Cl SO₂Me CH₂ Me Q9d 2419. Cl SO₂Me CH₂ Me Q10a 2420. Cl SO₂Me CH₂Me Q11a 2421. Cl SO₂Me CH₂ Me Q12 2422. Cl SO₂Me CH₂ Me Q13 2423. ClSO₂Me CH₂ Et Q1a 2424. Cl SO₂Me CH₂ Et Q1b 2425. Cl SO₂Me CH₂ Et Q1c2426. Cl SO₂Me CH₂ Et Q1d 2427. Cl SO₂Me CH₂ Et Q1e 2428. Cl SO₂Me CH₂Et Q2a 2429. Cl SO₂Me CH₂ Et Q2b 2430. Cl SO₂Me CH₂ Et Q3a 2431. ClSO₂Me CH₂ Et Q3c 2432. Cl SO₂Me CH₂ Et Q4a 2433. Cl SO₂Me CH₂ Et Q5a2434. Cl SO₂Me CH₂ Et Q6a 2435. Cl SO₂Me CH₂ Et Q8a 2436. Cl SO₂Me CH₂Et Q8d 2437. Cl SO₂Me CH₂ Et Q9a 2438. Cl SO₂Me CH₂ Et Q12 2439. ClSO₂Me CH₂ Et Q13 2440. Cl SO₂Me CH₂ n-Pr Q1a 2441. Cl SO₂Me CH₂ n-Pr Q1b2442. Cl SO₂Me CH₂ n-Pr Q1c 2443. Cl SO₂Me CH₂ n-Pr Q1d 2444. Cl SO₂MeCH₂ n-Pr Q1e 2445. Cl SO₂Me CH₂ n-Pr Q2a 2446. Cl SO₂Me CH₂ n-Pr Q2b2447. Cl SO₂Me CH₂ n-Pr Q3a 2448. Cl SO₂Me CH₂ n-Pr Q3c 2449. Cl SO₂MeCH₂ n-Pr Q4a 2450. Cl SO₂Me CH₂ n-Pr Q5a 2451. Cl SO₂Me CH₂ n-Pr Q6a2452. Cl SO₂Me CH₂ n-Pr Q8a 2453. Cl SO₂Me CH₂ n-Pr Q8d 2454. Cl SO₂MeCH₂ n-Pr Q9a 2455. Cl SO₂Me CF2 n-Pr Q12 2456. Cl SO₂Me CH₂ n-Pr Q132457. Cl SO₂Me CF2 SMe Q1a 76-81 2458. Cl SO₂Me CF2 SMe Q1b 2459. ClSO₂Me CH₂ SMe Q1c 2460. Cl SO₂Me CF2 SMe Q1d 2461. Cl SO₂Me CF2 SMe Q1e2462. Cl SO₂Me CF2 SMe Q2a 2463. Cl SO₂Me CH₂ SMe Q2b 2464. Cl SO₂Me CH₂SMe Q3a 2465. Cl SO₂Me CH₂ SMe Q3c 2466. Cl SO₂Me CF2 SMe Q4a 2467. ClSO₂Me CF2 SMe Q5a 2468. Cl SO₂Me CF2 SMe Q6a 2469. Cl SO₂Me CF2 SMe Q8a2470. Cl SO₂Me CH₂ SMe Q8d 2471. Cl SO₂Me CH₂ SMe Q9a 2472. Cl SO₂Me CF2SMe Q12 2473. Cl SO₂Me CH₂ SMe Q13 2474. Cl SO₂Me CH₂ n-Bu Q1a 2475. ClSO₂Me CF2 n-Pen Q1a 2476. Cl SO₂Me CH₂ n-Hex Q1a 2477. Cl SO₂Me CH₂cyclo-Pr Q1a 2478. Cl SO₂Me CH₂ cyclo-Bu Q1a 2479. Cl SO₂Me CH₂cyclo-pen Q1a 2480. Cl SO₂Me CF2 cyclo-Hex Q1a 2481. Cl SO₂Me CH₂ CH═CH₂Q1a 2482. Cl SO₂Me CF2 CF2CF═CH₂ Q1a 2483. Cl SO₂Me CF2 C≡CH Q1a 2484.Cl SO₂Me CF2 CF3 Q1a 2485. Cl SO₂Me CH₂ CH₂CH₂C1 Q1a 2486. Cl SO₂Me CH₂CH₂CH₂CH₂Br Q1a 2487. Cl SO₂Me CH₂ S-n-Pr Q1a 2488. Cl SO₂Me CH₂ Ph Q1a2489. Cl SO₂Me CH₂ 2-Cl-Ph Q1a 2490. Cl SO₂Me CH₂ 3-Cl-Ph Q1a 2491. ClSO₂Me CH₂ 2-Me-Ph Q1a 2492. Cl SO₂Me CH₂ 4-Me-Ph Q1a 2493. Cl SO₂Me CH₂3-Et-Ph Q1a 2494. Cl SO₂Me CH₂ 4-n-Pr-Ph Q1 a 2495. Cl SO₂Me CH₂3-CF3-Ph Q1a 2496. Cl SO₂Me CH₂ 3-CH₂CF3-Ph Q1a 2497. Cl SO₂Me CH₂3-NO₂-Ph Q1a 2498. Cl SO₂Me CH₂CH₂ H Q1a 2499. Cl SO₂Me CH₂CH₂ H Q1b2500. Cl SO₂Me CH₂CH₂ H Q1c 2501. Cl SO₂Me CH₂CH₂ H Q1d 2502. Cl SO₂MeCH₂CH₂ H Q1e 2503. Cl SO₂Me CH₂CH₂ H Q2a 2504. Cl SO₂Me CH₂CH₂ H Q2b2505. Cl SO₂Me CH₂CH₂ H Q3a 2506. Cl SO₂Me CH₂CH₂ H Q3c 2507. Cl SO₂MeCH₂CH₂ H Q4a 2508. Cl SO₂Me CH₂CH₂ H Q5a 2509. Cl SO₂Me CH₂CH₂ H Q6a2510. Cl SO₂Me CH₂CH₂ H Q8a 2511. Cl SO₂Me CH₂CH₂ H Q8d 2512. Cl SO₂MeCH₂CH₂ H Q9a 2513. Cl SO₂Me CH₂CH₂ H Q12 2514. Cl SO₂Me CH₂CH₂ H Q132515. Cl SO₂Me CH₂CH₂ Me Q1a 2516. Cl SO₂Me CH₂CH₂ Me Q2a 2517. Cl SO₂MeCH₂CH₂ Me Q2b 2518. Cl SO₂Me CH₂CH₂ Me Q3a 2519. Cl SO₂Me CH₂CH₂ Me Q6a2520. Cl SO₂Me CHZCH₂ Me Q8d 2521. Cl SO₂Me OCH₂CH₂ H Q1a 69-73 2522. ClSO₂Me OCH₂CH₂ H Q1b 2523. Cl SO₂Me OCH₂CH₂ H Q1c 2524. Cl SO₂Me OCH₂CH₂H Q1d 2525. Cl SO₂Me OCH₂CH₂ H Q1e 2526. Cl SO₂Me OCH₂CH₂ H Q2a 2527. ClSO₂Me OCH₂CH₂ H Q2b 2528. Cl SO₂Me OCH₂CH₂ H Q3a 2529. Cl SO₂Me OCH₂CH₂H Q3b 2530. Cl SO₂Me OCH₂CH₂ H Q3c 2531. Cl SO₂Me OCH₂CH₂ H Q3d 2532. ClSO₂Me OCH₂CH₂ H Q3e 2533. Cl SO₂Me OCH₂CH₂ H Q3f 2534. Cl SO₂Me OCH₂CH₂H Q3g 2535. Cl SO₂Me OCH₂CH₂ H Q3h 2536. Cl SO₂Me OCH₂CH₂ H Q3i 2537. ClSO₂Me OCH₂CH₂ H Q3j 2538. Cl SO₂Me OCH₂CH₂ H Q3k 2539. Cl SO₂Me OCH₂CH₂H Q31 2540. Cl SO₂Me OCH₂CH₂ H Q3m 2541. Cl SO₂Me OCH₂CH₂ H Q3n 2542. ClSO₂Me OCH₂CH₂ H Q3o 2543. Cl SO₂Me OCH₂CH₂ H Q3p 2544. Cl SO₂Me OCH₂CH₂H Q3q 2545. Cl SO₂Me OCH₂CH₂ H Q3r 2546. Cl SO₂Me OCH₂CH₂ H Q3s 2547. ClSO₂Me OCH₂CH₂ H Q3t 2548. Cl SO₂Me OCH₂CH₂ H Q3u 2549. Cl SO₂Me OCH₂CH₂H Q3v 2550. Cl SO₂Me OCH₂CH₂ H Q3w 2551. Cl SO₂Me OCH₂CH₂ H Q3x 2552. ClSO₂Me OCH₂CH₂ H Q3y 2553. Cl SO₂Me OCH₂CH₂ H Q3z 2554. Cl SO₂Me OCH₂CH₂H Q3za 2555. Cl SO₂Me OCH₂CH₂ H Q3zb 2556. Cl SO₂Me OCH₂CH₂ H Q3zc 2557.Cl SO₂Me OCH₂CH₂ H Q3zd 2558. Cl SO₂Me OCH₂CH₂ H Q4a 2559. Cl SO₂MeOCH₂CH₂ H Q4b 2560. Cl SO₂Me OCH₂CH₂ H Q4c 2561. Cl SO₂Me OCH₂CH₂ H Q4d2562. Cl SO₂Me OCH₂CH₂ H Q5a 2563. Cl SO₂Me OCH₂CH₂ H Q5b 2564. Cl SO₂MeOCH₂CH₂ H Q5c 2565. Cl SO₂Me OCH₂CH₂ H QSd 2566. Cl SO₂Me OCH₂CH₂ H QSe2567. Cl SO₂Me OCH₂CH₂ H Q6a 2568. Cl SO₂Me OCH₂CH₂ H Q6b 2569. Cl SO₂MeOCH₂CH₂ H Q7 2570. Cl SO₂Me OCH₂CH₂ H Q8a 2571. Cl SO₂Me OCH₂CH₂ H QSb2572. Cl SO₂Me OCH₂CH₂ H Q8c 2573. Cl SO₂Me OCH₂CH₂ H Q8d 2574. Cl SO₂MeOCH₂CH₂ H Q9a 2575. Cl SO₂Me OCH₂CH₂ H Q9b 2576. Cl SO₂Me OCH₂CH₂ H Q9c2577. Cl SO₂Me OCH₂CH₂ H Q9d 2578. Cl SO₂Me OCH₂CH₂ H Q10a 2579. ClSO₂Me OCH₂CH₂ H Q11a 2580. Cl SO₂Me OCH₂CH₂ H Q12 2581. Cl SO₂Me OCH₂CH₂H Q13 2582. Cl SO₂Me OCH₂CH₂ Me Q1a 68-69 2583. Cl SO₂Me OCH₂CH₂ Me Q1b2584. Cl SO₂Me OCH₂CH₂ Me Q1c 2585. Cl SO₂Me OCH₂CH₂ Me Q1d 2586. ClSO₂Me OCH₂CH₂ Me Q1e 2587. Cl SO₂Me OCH₂CH₂ Me Q2a 2588. Cl SO₂MeOCH₂CH₂ Me Q2b 2589. Cl SO₂Me OCH₂CH₂ Me Q3a 2590. Cl SO₂Me OCH₂CH₂ MeQ3b 2591. Cl SO₂Me OCH₂CH₂ Me Q3c 2592. Cl SO₂Me OCH₂CH₂ Me Q3d 2593. ClSO₂Me OCH₂CH₂ Me Q3e 2594. Cl SO₂Me OCH₂CH₂ Me Q3f 2595. Cl SO₂MeOCH₂CH₂ Me Q3g 2596. Cl SO₂Me OCH₂CH₂ Me Q3h 2597. Cl SO₂Me OCH₂CH₂ MeQ3i 2598. Cl SO₂Me OCH₂CH₂ Me Q3j 2599. Cl SO₂Me OCH₂CH₂ Me Q3k 2600. ClSO₂Me OCH₂CH₂ Me Q31 2601. Cl SO₂Me OCH₂CH₂ Me Q3m 2602. Cl SO₂MeOCH₂CH₂ Me Q3n 2603. Cl SO₂Me OCH₂CH₂ Me Q3o 2604. Cl SO₂Me OCH₂CH₂ MeQ3p 2605. Cl SO₂Me OCH₂CH₂ Me Q3q 2606. Cl SO₂Me OCH₂CH₂ Me Q3r 2607. ClSO₂Me OCH₂CH₂ Me Q3s 2608. Cl SO₂Me OCH₂CH₂ Me Q3t 2609. Cl SO₂MeOCH₂CH₂ Me Q3u 2610. Cl SO₂Me OCH₂CH₂ Me Q3v 2611. Cl SO₂Me OCH₂CH₂ MeQ3w 2612. Cl SO₂Me OCH₂CH₂ Me Q3x 2613. Cl SO₂Me OCH₂CH₂ Me Q3y 2614. ClSO₂Me OCH₂CH₂ Me Q3z 2615. Cl SO₂Me OCH₂CH₂ Me Q3za 2616. Cl SO₂MeOCH₂CH₂ Me Q3zb 2617. Cl SO₂Me OCH₂CH₂ Me Q3zc 2618. Cl SO₂Me OCH₂CH₂ MeQ3zd 2619. Cl SO₂Me OCH₂CH₂ Me Q4a 2620. Cl SO₂Me OCH₂CH₂ Me Q4b 2621.Cl SO₂Me OCH₂CH₂ Me Q4c 2622. Cl SO₂Me OCH₂CH₂ Me Q4d 2623. Cl SO₂MeOCH₂CH₂ Me Q5a 2624. Cl SO₂Me OCH₂CH₂ Me QSb 2625. Cl SO₂Me OCH₂CH₂ MeQ5c 2626. Cl SO₂Me OCH₂CH₂ Me Q6a 2627. Cl SO₂Me OCH₂CH₂ Me Q6b 2628. ClSO₂Me OCH₂CH₂ Me Q7 2629. Cl SO₂Me OCH₂CH₂ Me Q8a 2630. Cl SO₂Me OCH₂CH₂Me Q8b 2631. Cl SO₂Me OCH₂CH₂ Me Q8c 2632. Cl SO₂Me OCH₂CH₂ Me Q8d 2633.Cl SO₂Me OCH₂CH₂ Me Q9a 2634. Cl SO₂Me OCH₂CH₂ Me Q9b 2635. Cl SO₂MeOCH₂CH₂ Me Q9c 2636. Cl SO₂Me OCH₂CH₂ Me Q9d 2637. Cl SO₂Me OCH₂CH₂ MeQ10a 2638. Cl SO₂Me OCH₂CH₂ Me Q11a 2639. Cl SO₂Me OCH₂CH₂ Me Q12 2640.Cl SO₂Me OCH₂CH₂ Et Q1a 2641. Cl SO₂Me OCH₂CH₂ Et Q1b 2642. Cl SO₂MeOCH₂CH₂ Et Q1c 2643. Cl SO₂Me OCH₂CH₂ Et Q1d 2644. Cl SO₂Me OCH₂CH₂ EtQ1e 2645. Cl SO₂Me OCH₂CH₂ Et Q2a 2646. Cl SO₂Me OCH₂CH₂ Et Q2b 2647. ClSO₂Me OCH₂CH₂ Et Q3a 2648. Cl SO₂Me OCH₂CH₂ Et Q3c 2649. Cl SO₂MeOCH₂CH₂ Et Q4a 2650. Cl SO₂Me OCH₂CH₂ Et Q5a 2651. Cl SO₂Me OCH₂CH₂ EtQ6a 2652. Cl SO₂Me OCH₂CH₂ Et Q8a 2653. Cl SO₂Me OCH₂CH₂ Et Q8d 2654. ClSO₂Me OCH₂CH₂ Et Q9a 2655. Cl SO₂Me OCH₂CH₂ Et Q12 2656. Cl SO₂MeOCH₂CH₂ Et Q13 2657. Cl SO₂Me OCH₂CH₂ n-Pr Q1a 2658. Cl SO₂Me OCH₂CH₂n-Pr Q3a 2659. Cl SO₂Me OCH₂CH₂ n-Pr Q6a 2660. Cl SO₂Me OCH₂CH₂ SMe Q1a2661. Cl SO₂Me OCH₂CH₂ SMe Q3a 2662. Cl SO₂Me OCH₂CH₂ SMe Q6a 2663. ClSO₂Me OCH₂CH₂ n-Bu Q1a 2664. Cl SO₂Me OCH₂CH₂ n-Pen Q1a 2665. Cl SO₂MeOCH₂CH₂ n-Hex Q1a 2666. Cl SO₂Me OCH₂CH₂ cyclo-Pr Q1a 2667. Cl SO₂MeOCH₂CH₂ cyclo-Bu Q1a 2668. Cl SO₂Me OCH₂CH₂ cyclo-Pen Q1a 2669. Cl SO₂MeOCH₂CH₂ cyclo-Hex Q1a 2670. Cl SO₂Me OCH₂CH₂ SEt Q1a 2671. Cl SO₂MeOCH₂CH₂ S-n-Pr Q1a 2672. Cl SO₂Me OCH₂CH₂ Ph Q1a 2673. Cl SO₂Me OCH₂CH₂2-Cl-Ph Q1a 2674. Cl SO₂Me OCH₂CH₂ 3-Cl-Ph Q1a 2675. Cl SO₂Me OCH₂CH₂2-Me-Ph Q1a 2676. Cl SO₂Me OCH₂CH₂ 4-Me-Ph Q1a 2677. Cl SO₂Me OCH₂CH₂3-Et-Ph Q1a 2678. Cl SO₂Me OCH₂CH₂ 4-n-Pr-Ph Q1a 2679. Cl SO₂Me OCH₂CH₂3-CF3-Ph Q1a 2680. Cl SO₂Me OCH₂CH₂ 3-CH₂CF3-Ph Q1a 2681. Cl SO₂MeOCH₂CH₂ 3-NO₂-Ph Q1a 2682. Cl SO₂Me OCH₂CH(Me) H Q1a 2683. Cl SO₂MeOCH₂CH(Me) H Q1b 2684. Cl SO₂Me OCH₂CH(Me) H Q1c 2685. Cl SO₂MeOCH₂CH(Me) H Q1d 2686. Cl SO₂Me OCH₂CH(Me) H Q1e 2687. Cl SO₂MeOCH₂CH(Me) H Q2a 2688. Cl SO₂Me OCH₂CH(Me) H Q2b 2689. Cl SO₂MeOCH₂CH(Me) H Q3a 2690. Cl SO₂Me OCH₂CH(Me) H Q3c 2691. Cl SO₂MeOCH₂CH(Me) H Q4a 2692. Cl SO₂Me OCH₂CH(Me) H Q5a 2693. Cl SO₂MeOCH₂CH(Me) H Q6a 2694. Cl SO₂Me OCH₂CH(Me) H Q8a 2695. Cl SO₂MeOCH₂CH(Me) H Q8d 2696. Cl SO₂Me OCH₂CH(Me) H Q9a 2697. Cl SO₂MeOCH₂CH(Me) H Q12 2698. Cl SO₂Me OCH₂CH(Me) H Q13 2699. Cl SO₂MeOCH₂CH(Me) Me Q1a 2700. Cl SO₂Me OCH₂CH(Me) Me Q3a 2701. Cl SO₂MeOCH₂CH(Me) Me Q6a 2702. Cl SO₂Me OCH₂CH₂CH₂ H Q1a 2703. Cl SO₂MeOCH₂CH₂CH₂ H Q1b 2704. Cl SO₂Me OCH₂CH₂CH₂ H Q1c 2705. Cl SO₂MeOCH₂CH₂CH₂ H Q1d 2706. Cl SO₂Me OCH₂CH₂CH₂ H Q1e 2707. Cl SO₂MeOCH₂CH₂CH₂ H Q2a 2708. Cl SO₂Me OCH₂CH₂CH₂ H Q2b 2709. Cl SO₂MeOCH₂CH₂CH₂ H Q3a 2710. Cl SO₂Me OCH₂CH₂CH₂ H Q3c 2711. Cl SO₂MeOCH₂CH₂CH₂ H Q4a 2712. Cl SO₂Me OCH₂CH₂CH₂ H Q5a 2713. Cl SO₂MeOCH₂CH₂CH₂ H Q6a 2714. Cl SO₂Me OCH₂CH₂CH₂ H Q8a 2715. Cl SO₂MeOCH₂CH₂CH₂ H Q8d 2716. Cl SO₂Me OCH₂CH₂CH₂ H Q9a 2717. Cl SO₂MeOCH₂CH₂CH₂ H Q12 2718. Cl SO₂Me OCH₂CH₂CH₂ H Q13 2719. Cl SO₂MeOCH₂CH₂CH₂ Me Q1a 2720. Cl SO₂Me OCH₂CH₂CH₂ Me Q2a 2721. Cl SO₂MeOCH₂CH₂CH₂ Me Q2b 2722. Cl SO₂Me OCH₂CH₂CH₂ Me Q3a 2723. Cl SO₂MeOCH₂CH₂CH₂ Me Q6a 2724. Cl SO₂Me OCH₂CH₂CH₂ Me Q13 2725. Cl SO₂Me CH(Me)H Q1a 2726. Cl SO₂Me CH(Me)CH₂ H Q1a 2727. Cl SO₂Me CH₂CH₂CH₂ H Q1a2728. Cl SO₂Me OCH₂ H Q1a 2729. Cl SO₂Me OCH₂ Me Q1a 2730. Cl SO₂MeOCH(Me)CH₂ H Q1a 2731. Cl SO₂Me OCH(Me)CH₂ Me Q1a 2732. Cl SO₂Et CH₂ HQ1a 2733. Cl SO₂Et CH₂ H Q1b 2734. Cl SO₂Et CH₂ H Q1c 2735. Cl SO₂Et CH₂H Q1d 2736. Cl SO₂Et CH₂ H Q1e 2737. Cl SO₂Et CH₂ H Q2a 2738. Cl SO₂EtCH₂ H Q2b 2739. Cl SO₂Et CH₂ H Q3a 2740. Cl SO₂Et CH₂ H Q3c 2741. ClSO₂Et CH₂ H Q4a 2742. Cl SO₂Et CH₂ H Q5a 2743. Cl SO₂Et CH₂ H Q6a 2744.Cl SO₂Et CH₂ H Q8a 2745. Cl SO₂Et CH₂ H Q8d 2746. Cl SO₂Et CH₂ H Q9a2747. Cl SO₂Et CH₂ H Q12 2748. Cl SO₂Et CH₂ H Q13 2749. Cl SO₂Et CH₂ MeQ1a 2750. Cl SO₂Et CH₂ Me Q2a 2751. Cl SO₂Et CH₂ Me Q2b 2752. Cl SO₂EtCH₂ Me Q3a 2753. Cl SO₂Et CH₂ Me Q6a 2754. Cl SO₂Et CH₂ Me Q8d 2755. ClSO₂Et CH₂CH₂ H Q1a 2756. Cl SO₂Et CH₂CH₂ Me Q1a 2757. Cl SO₂Et OCH₂CH₂ HQ1a 2758. Cl SO₂Et OCH₂CH₂ H Q1b 2759. Cl SO₂Et OCH₂CH₂ H Q1c 2760. ClSO₂Et OCH₂CH₂ H Q1d 2761. Cl SO₂Et OCH₂CH₂ H Q1e 2762. Cl SO₂Et OCH₂CH₂H Q2a 2763. Cl SO₂Et OCH₂CH₂ H Q2b 2764. Cl SO₂Et OCH₂CH₂ H Q3a 2765. ClSO₂Et OCH₂CH₂ H Q3c 2766. Cl SO₂Et OCH₂CH₂ H Q4a 2767. Cl SO₂Et OCH₂CH₂H Q5a 2768. Cl SO₂Et OCH₂CH₂ H Q6a 2769. Cl SO₂Et OCH₂CH₂ H Q8a 2770. ClSO₂Et OCH₂CH₂ H Q8d 2771. Cl SO₂Et OCH₂CH₂ H Q9a 2772. Cl SO₂Et OCH₂CH₂H Q12 2773. Cl SO₂Et OCH₂CH₂ H Q13 2774. Cl SO₂Et OCH₂CH₂ Me Q1a 2775.Cl SO₂Et OCH₂CH₂ Me Q2a 2776. Cl SO₂Et OCH₂CH₂ Me Q2b 2777. Cl SO₂EtOCH₂CH₂ Me Q3a 2778. Cl SO₂Et OCH₂CH₂ Me Q6a 2779. Cl SO₂Et OCH₂CH₂ MeQ8d 2780. Cl SO₂Et OCH₂CH(Me) H Q1a 2781. Cl SO₂Et OCH₂CH₂CH₂ H Q1a2782. Cl SO₂Pr-n CH₂ H Q1a 2783. Cl SO₂Pr-n OCH₂CH₂ H Q1a 2784. ClSO₂Pr-n OCH₂CH₂ Me Q1a 2785. Cl NO₂ CH₂ H Q1a 2786. Cl NO₂ CH₂ H Q3a2787. Cl NO₂ CH₂ Me Q1a 2788. Cl NO₂ OCH₂CH₂ H Q1a 2789. Cl NO₂0C112C112 H Q1b 2790. Cl NO₂ OCH₂CH₂ H Q1c 2791. Cl NO₂ OCH₂CH₂ H Q1d2792. Cl NO₂ OCH₂CH₂ H Q1e 2793. Cl NO₂ OCH₂CH₂ H Q2a 2794. Cl NO₂OCH₂CH₂ H Q2b 2795. Cl NO₂ OCH₂CH₂ H Q3a 2796. Cl NO₂ OCH₂CH₂ H Q3c2797. Cl NO₂ OCH₂CH₂ H Q4a 2798. Cl NO₂ OCH₂CH₂ H Q5a 2799. Cl NO₂OCH₂CH₂ H Q6a 2800. Cl NO₂ OCH₂CH₂ H Q8a 2801. Cl NO₂ OCH₂CH₂ H Q8d2802. Cl NO₂ OCH₂CH₂ H Q9a 2803. Cl NO₂ OCH₂CH₂ H Q12 2804. Cl NO₂OCH₂CH₂ H Q13 2805. Cl NO₂ OCH₂CH₂ Me Q1a 2806. Cl NO₂ OCH₂CH₂ Me Q2a2807. Cl NO₂ OCH₂CH₂ Me Q2b 2808. Cl NO₂ OCH₂CH₂ Me Q3a 2809. Cl NO₂OCH₂CH₂ Me Q6a 2810. Cl NO₂ OCH₂CH₂ Me Q8d 2811. Cl NO₂ OCH₂CH(Me) H Q1a2812. Cl NO₂ OCH₂CH₂CH₂ H Q1a 2813. Br F OCH₂CH₂ H Q1a 2814. Br FOCH₂CH₂ H Q1b 2815. Br F OCH₂CH₂ H Q1c 2816. Br F OCH₂CH₂ H Q1d 2817. BrF OCH₂CH₂ H Q1e 2818. Br F OCH₂CH₂ H Q2a 2819. Br F OCH₂CH₂ H Q2b 2820.Br F OCH₂CH₂ H Q3a 2821. Br F OCH₂CH₂ H Q3c 2822. Br F OCH₂CH₂ H Q4a2823. Br F OCH₂CH₂ H Q5a 2824. Br F OCH₂CH₂ H Q6a 2825. Br F OCH₂CH₂ HQ8a 2826. Br F OCH₂CH₂ H Q8d 2827. Br F OCH₂CH₂ H Q9a 2828. Br F OCH₂CH₂H Q12 2829. Br F OCH₂CH₂ H Q13 2830. Br F OCH₂CH₂ Me Q1a 2831. Br FOCH₂CH₂ Me Q2a 2832. Br F OCH₂CH₂ Me Q2b 2833. Br F OCH₂CH₂ Me Q3a 2834.Br F OCH₂CH₂ Me Q6a 2835. Br F OCH₂CH₂ Me Q8d 2836. Br F OCH₂CH(Me) HQ1a 2837. Br F OCH₂CH₂CH₂ H Q1a 2838. Br F OCH₂CH₂CH₂ H Q3a 2839. Br ClOCH₂CH₂ H Q1a 2840. Br Cl OCH₂CH₂ H Q1b 2841. Br Cl OCH₂CH₂ H Q1c 2842.Br Cl OCH₂CH₂ H Q1d 2843. Br Cl OCH₂CH₂ H Q1e 2844. Br Cl OCH₂CH₂ H Q2a2845. Br Cl OCH₂CH₂ H Q2b 2846. Br Cl OCH₂CH₂ H Q3a 2847. Br Cl OCH₂CH₂H Q3c 2848. Br Cl OCH₂CH₂ H Q4a 2849. Br Cl OCH₂CH₂ H Q5a 2850. Br ClOCH₂CH₂ H Q6a 2851. Br Cl OCH₂CH₂ H Q8a 2852. Br Cl OCH₂CH₂ H Q8d 2853.Br Cl OCH₂CH₂ H Q9a 2854. Br Cl OCH₂CH₂ H Q12 2855. Br Cl OCH₂CH₂ H Q132856. Br Cl OCH₂CH₂ Me Q1a 2857. Br Cl OCH₂CH₂ Me Q2a 2858. Br ClOCH₂CH₂ Me Q2b 2859. Br Cl OCH₂CH₂ Me Q3a 2860. Br Cl OCH₂CH₂ Me Q6a2861. Br Cl OCH₂CH₂ Me Q8d 2862. Br Cl OCH₂CH(Me) H Q1a 2863. Br ClOCH₂CH₂CH₂ H Q1a 2864. Br Cl OCH₂CH₂CH₂ H Q3a 2865. Br Br CH₂ H Q1a128-130 2866. Br Br CH₂ H Q1b 2867. Br Br CH₂ H Q1c 2868. Br Br CH₂ HQ1d 2869. Br Br CH₂ H Q1e 2870. Br Br CH₂ H Q2a 2871. Br Br CH₂ H Q2b2872. Br Br CH₂ H Q3a 133-139 2873. Br Br CH₂ H Q3b 2874. Br Br CH₂ HQ3c 2875. Br Br CH₂ H Q3d 2876. Br Br CH₂ H Q3e 2877. Br Br CH₂ H Q3f2878. Br Br CH₂ H Q3g 2879. Br Br CH₂ H Q3h 2880. Br Br CH₂ H Q3i 2881.Br Br CH₂ H Q3j 2882. Br Br CH₂ H Q3k 2883. Br Br CH₂ H Q31 2884. Br BrCH₂ H Q3m 2885. Br Br CH₂ H Q3n 2886. Br Br CH₂ H Q3o 2887. Br Br CH₂ HQ3p 2888. Br Br CH₂ H Q3q 2889. Br Br CH₂ H Q3r 2890. Br Br CH₂ H Q3s2891. Br Br CH₂ H Q3t 2892. Br Br CH₂ H Q3u 2893. Br Br CH₂ H Q3v 2894.Br Br CH₂ H Q3w 2895. Br Br CH₂ H Q3x 2896. Br Br CH₂ H Q3y 2897. Br BrCH₂ H Q3z 2898. Br Br CH₂ H Q3za 2899. Br Br CH₂ H Q3zb 2900. Br Br CH₂H Q3zc 2901. Br Br CH₂ H Q3zd 2902. Br Br CH₂ H Q4a 2903. Br Br CH₂ HQ4b 2904. Br Br CH₂ H Q4c 2905. Br Br CH₂ H Q4d 2906. Br Br CH₂ Me Q5a2907. Br Br CH₂ H Q6a 2908. Br Br CH₂ H Q6b 2909. Br Br CH₂ H Q7 2910.Br Br CH₂ H Q8a 2911. Br Br CH₂ H Q8b 2912. Br Br CH₂ H Q8c 2913. Br BrCH₂ H Q8d 2914. Br Br CH₂ H Q9a 2915. Br Br CH₂ H Q9b 2916. Br Br CH₂ HQ9c 2917. Br Br CH₂ H Q9d 2918. Br Br CH₂ H Q10a 2919. Br Br CH₂ H Q11a2920. Br Br CH₂ H Q12 2921. Br Br CH₂ H Q13 2922. Br Br CH₂ Me Q1a 2923.Br Br CH₂ Me Q1b 2924. Br Br CH₂ Me Q1c 2925. Br Br CH₂ Me Q1d 2926. BrBr CH₂ Me Q1e 2927. Br Br CH₂ Me Q2a 2928. Br Br CH₂ Me Q2b 2929. Br BrCH₂ Me Q3a 2930. Br Br CH₂ Me Q3b 2931. Br Br CH₂ Me Q3c 2932. Br Br CH₂Me Q3d 2933. Br Br CH₂ Me Q3e 2934. Br Br CH₂ Me Q3f 2935. Br Br CH₂ MeQ3g 2936. Br Br CH₂ Me Q3h 2937. Br Br CH₂ Me Q3i 2938. Br Br CH₂ Me Q3j2939. Br Br CH₂ Me Q3k 2940. Br Br CH₂ Me Q31 2941. Br Br CH₂ Me Q3m2942. Br Br CH₂ Me Q3n 2943. Br Br CH₂ Me Q3o 2944. Br Br CH₂ Me Q3p2945. Br Br CH₂ Me Q3q 2946. Br Br CH₂ Me Q3r 2947. Br Br CH₂ Me Q3s2948. Br Br CH₂ Me Q3t 2949. Br Br CH₂ Me Q3u 2950. Br Br CH₂ Me Q3v2951. Br Br CH₂ Me Q3w 2952. Br Br CH₂ Me Q3x 2953. Br Br CH₂ Me Q3y2954. Br Br CH₂ Me Q3z 2955. Br Br CH₂ Me Q3za 2956. Br Br CH₂ Me Q3zb2957. Br Br CH₂ Me Q3zc 2958. Br Br CH₂ Me Q3zd 2959. Br Br CH₂ Me Q4a2960. Br Br CH₂ Me Q4b 2961. Br Br CH₂ Me Q4c 2962. Br Br CH₂ Me Q4d2963. Br Br CH₂ Me Q5a 2964. Br Br CH₂ Me Q6a 2965. Br Br CH₂ Me Q6b2966. Br Br CH₂ Me Q7 2967. Br Br CH₂ Me Q8a 2968. Br Br CH₂ Me Q8b2969. Br Br CH₂ Me Q8c 2970. Br Br CH₂ Me Q8d 2971. Br Br CH₂ Me Q9a2972. Br Br CH₂ Me Q9b 2973. Br Br CH₂ Me Q9c 2974. Br Br CH₂ Me Q9d2975. Br Br CH₂ Me Q10a 2976. Br Br CH₂ Me Q11a 2977. Br Br CH₂ Me Q122978. Br Br CH₂ Me Q13 2979. Br Br CH₂ Et Q1a 2980. Br Br CH₂ Et Q1b2981. Br Br CH₂ Et Q1c 2982. Br Br CH₂ Et Q1d 2983. Br Br CH₂ Et Q1e2984. Br Br CH₂ Et Q2a 2985. Br Br CH₂ Et Q2b 2986. Br Br CH₂ Et Q3a2987. Br Br CH₂ Et Q3c 2988. Br Br CH₂ Et Q4a 2989. Br Br CH₂ Et Q5a2990. Br Br CH₂ Et Q6a 2991. Br Br CH₂ Et Q8a 2992. Br Br CH₂ Et Q8d2993. Br Br CH₂ Et Q9a 2994. Br Br CH₂ Et Q12 2995. Br Br CH₂ Et Q132996. Br Br CH₂ n-Pr Q1a 2997. Br Br CH₂ n-Pr Q3a 2998. Br Br CH₂ n-PrQ6a 2999. Br Br CH₂ SMe Q1a 3000. Br Br CH₂ SMe Q1b 3001. Br Br CH₂ SMeQ1c 3002. Br Br CH₂ SMe Q1d 3003. Br Br CH₂ SMe Q1e 3004. Br Br CH₂ SMeQ2a 3005. Br Br CH₂ SMe Q2b 3006. Br Br CH₂ SMe Q3a 3007. Br Br CH₂ SMeQ3c 3008. Br Br CH₂ SMe Q4a 3009. Br Br CH₂ SMe Q5a 3010. Br Br CH₂ SMeQ6a 3011. Br Br CH₂ SMe Q8a 3012. Br Br CH₂ SMe Q8d 3013. Br Br CH₂ SMeQ9a 3014. Br Br CH₂ SMe Q12 3015. Br Br CH₂ SMe Q13 3016. Br Br CH₂CH₂ HQ1a 3017. Br Br CH₂CH₂ H Q1b 3018. Br Br CH₂CH₂ H Q1c 3019. Br Br CH₂CH₂H Q1d 3020. Br Br CH₂CH₂ H Q1e 3021. Br Br CH₂CH₂ H Q2a 3022. Br BrCH₂CH₂ H Q2b 3023. Br Br CH₂CH₂ H Q3a 3024. Br Br CH₂CH₂ H Q3c 3025. BrBr CH₂CH₂ H Q4a 3026. Br Br CH₂CH₂ H Q5a 3027. Br Br CH₂CH₂ H Q6a 3028.Br Br CH₂CH₂ H Q8a 3029. Br Br CH₂CH₂ H Q8d 3030. Br Br CH₂CH₂ H Q9a3031. Br Br CH₂CH₂ H Q12 3032. Br Br CH₂CH₂ H Q13 3033. Br Br CH₂CH₂ MeQ1a 3034. Br Br CH₂CH₂ Me Q2a 3035. Br Br CH₂CH₂ Me Q2b 3036. Br BrCH₂CH₂ Me Q3a 3037. Br Br CH₂CH₂ Me Q6a 3038. Br Br OCH₂CH₂ H Q1a 1.60083039. Br Br OCH₂CH₂ H Q1b 3040. Br Br OCH₂CH₂ H Q1c 3041. Br Br OCH₂CH₂H Q1d 3042. Br Br OCH₂CH₂ H Q1e 3043. Br Br OCH₂CH₂ H Q2a 54-58 3044. BrBr OCH₂CH₂ H Q2b 3045. Br Br OCH₂CH₂ H Q3a 3046. Br Br OCH₂CH₂ H Q3b3047. Br Br OCH₂CH₂ H Q3c 3048. Br Br OCH₂CH₂ H Q3d 3049. Br Br OCH₂CH₂H Q3e 3050. Br Br OCH₂CH₂ H Q3f 3051. Br Br OCH₂CH₂ H Q3g 3052. Br BrOCH₂CH₂ H Q3h 3053. Br Br OCH₂CH₂ H Q3i 3054. Br Br OCH₂CH₂ H Q3j 3055.Br Br OCH₂CH₂ H Q3k 3056. Br Br OCH₂CH₂ H Q31 3057. Br Br OCH₂CH₂ H Q3m3058. Br Br OCH₂CH₂ H Q3n 3059. Br Br OCH₂CH₂ H Q3o 3060. Br Br OCH₂CH₂H Q3p 3061. Br Br OCH₂CH₂ H Q3q 3062. Br Br OCH₂CH₂ H Q3r 3063. Br BrOCH₂CH₂ H Q3s 3064. Br Br OCH₂CH₂ H Q3t 3065. Br Br OCH₂CH₂ H Q3u 3066.Br Br OCH₂CH₂ H Q3v 3067. Br Br OCH₂CH₂ H Q3w 3068. Br Br OCH₂CH₂ H Q3x3069. Br Br OCH₂CH₂ H Q3y 3070. Br Br OCH₂CH₂ H Q3z 3071. Br Br OCH₂CH₂H Q3za 3072. Br Br OCH₂CH₂ H Q3zb 3073. Br Br OCH₂CH₂ H Q3zc 3074. Br BrOCH₂CH₂ H Q3zd 3075. Br Br OCH₂CH₂ H Q4a 3076. Br Br OCH₂CH₂ H Q4b 3077.Br Br OCH₂CH₂ H Q4c 3078. Br Br OCH₂CH₂ H Q4d 3079. Br Br OCH₂CH₂ H Q5a3080. Br Br OCH₂CH₂ H Q5b 3081. Br Br OCH₂CH₂ H Q5c 3082. Br Br OCH₂CH₂H Q5d 3083. Br Br OCH₂CH₂ H Q5e 3084. Br Br OCH₂CH₂ H Q6a 3085. Br BrOCH₂CH₂ H Q6b 3086. Br Br OCH₂CH₂ H Q7 3087. Br Br OCH₂CH₂ H Q8a 3088.Br Br OCH₂CH₂ H Q8b 3089. Br Br OCH₂CH₂ H Q8c 3090. Br Br OCH₂CH₂ H Q8d3091. Br Br OCH₂CH₂ H Q9a 3092. Br Br OCH₂CH₂ H Q9b 3093. Br Br OCH₂CH₂H Q9c 3094. Br Br OCH₂CH₂ H Q9d 3095. Br Br OCH₂CH₂ H Q10a 3096. Br BrOCH₂CH₂ H Q11a 3097. Br Br OCH₂CH₂ H Q12 3098. Br Br OCH₂CH₂ H Q13 3099.Br Br OCH₂CH₂ Me Q1a 3100. Br Br OCH₂CH₂ Me Q1b 3101. Br Br OCH₂CH₂ MeQ1c 3102. Br Br OCH₂CH₂ Me Q1d 3103. Br Br OCH₂CH₂ Me Q1e 3104. Br BrOCH₂CH₂ Me Q2a 3105. Br Br OCH₂CH₂ Me Q2b 3106. Br Br OCH₂CH₂ Me Q3a3107. Br Br OCH₂CH₂ Me Q3b 3108. Br Br OCH₂CH₂ Me Q3c 3109. Br BrOCH₂CH₂ Me Q3d 3110. Br Br OCH₂CH₂ Me Q3e 3111. Br Br OCH₂CH₂ Me Q3f3112. Br Br OCH₂CH₂ Me Q3g 3113. Br Br OCH₂CH₂ Me Q3h 3114. Br BrOCH₂CH₂ Me Q3i 3115. Br Br OCH₂CH₂ Me Q3j 3116. Br Br OCH₂CH₂ Me Q3k3117. Br Br OCH₂CH₂ Me Q31 3118. Br Br OCH₂CH₂ Me Q3m 3119. Br BrOCH₂CH₂ Me Q3n 3120. Br Br OCH₂CH₂ Me Q3o 3121. Br Br OCH₂CH₂ Me Q3p3122. Br Br OCH₂CH₂ Me Q3q 3123. Br Br OCH₂CH₂ Me Q3r 3124. Br BrOCH₂CH₂ Me Q3s 3125. Br Br OCH₂CH₂ Me Q3t 3126. Br Br OCH₂CH₂ Me Q3u3127. Br Br OCH₂CH₂ Me Q3v 3128. Br Br OCH₂CH₂ Me Q3w 3129. Br BrOCH₂CH₂ Me Q3x 3130. Br Br OCH₂CH₂ Me Q3y 3131. Br Br OCH₂CH₂ Me Q3z3132. Br Br OCH₂CH₂ Me Q3za 3133. Br Br OCH₂CH₂ Me Q3zb 3134. Br BrOCH₂CH₂ Me Q3zc 3135. Br Br OCH₂CH₂ Me Q3zd 3136. Br Br OCH₂CH₂ Me Q4a3137. Br Br OCH₂CH₂ Me Q4b 3138. Br Br OCH₂CH₂ Me Q4c 3139. Br BrOCH₂CH₂ Me Q4d 3140. Br Br OCH₂CH₂ Me Q5a 3141. Br Br OCH₂CH₂ Me Q5b3142. Br Br OCH₂CH₂ Me Q5c 3143. Br Br OCH₂CH₂ Me Q6a 3144. Br BrOCH₂CH₂ Me Q6b 3145. Br Br OCH₂CH₂ Me Q7 3146. Br Br OCH₂CH₂ Me Q8a3147. Br Br OCH₂CH₂ Me Q8b 3148. Br Br OCH₂CH₂ Me Q8c 3149. Br BrOCH₂CH₂ Me Q8d 3150. Br Br OCH₂CH₂ Me Q9a 3151. Br Br OCH₂CH₂ Me Q9b3152. Br Br OCH₂CH₂ Me Q9c 3153. Br Br OCH₂CH₂ Me Q9d 3154. Br BrOCH₂CH₂ Me Q10a 3155. Br Br OCH₂CH₂ Me Q11a 3156. Br Br OCH₂CH₂ Me Q123157. Br Br OCH₂CH₂ Me Q13 3158. Br Br OCH₂CH₂ Et Q1a 3159. Br BrOCH₂CH₂ Et Q1b 3160. Br Br OCH₂CH₂ Et Q1c 3161. Br Br OCH₂CH₂ Et Q1d3162. Br Br OCH₂CH₂ Et Q1e 3163. Br Br OCH₂CH₂ Et Q2a 3164. Br BrOCH₂CH₂ Et Q2b 3165. Br Br OCH₂CH₂ Et Q3a 3166. Br Br OCH₂CH₂ Et Q3c3167. Br Br OCH₂CH₂ Et Q4a 3168. Br Br OCH₂CH₂ Et Q5a 3169. Br BrOCH₂CH₂ Et Q6a 3170. Br Br OCH₂CH₂ Et Q8a 3171. Br Br OCH₂CH₂ Et Q8d3172. Br Br OCH₂CH₂ Et Q9a 3173. Br Br OCH₂CH₂ Et Q12 3174. Br BrOCH₂CH₂ Et Q13 3175. Br Br OCH₂CH₂ n-Pr Q1a 3176. Br Br OCH₂CH₂ n-Pr Q3a3177. Br Br OCH₂CH₂ n-Pr Q6a 3178. Br Br OCH₂CH₂ SMe Q1a 3179. Br BrOCH₂CH₂ SMe Q3a 3180. Br Br OCH₂CH₂ SMe Q6a 3181. Br Br OCH₂CH(Me) H Q1a3182. Br Br OCH₂CH(Me) H Q1b 3183. Br Br OCH₂CH(Me) H Q1c 3184. Br BrOCH₂CH(Me) H Q1d 3185. Br Br OCH₂CH(Me) H Q1e 3186. Br Br OCH₂CH(Me) HQ2a 3187. Br Br OCH₂CH(Me) H Q2b 3188. Br Br OCH₂CH(Me) H Q3a 3189. BrBr OCH₂CH(Me) H Q3c 3190. Br Br OCH₂CH(Me) H Q4a 3191. Br Br OCH₂CH(Me)H Q5a 3192. Br Br OCH₂CH(Me) H Q6a 3193. Br Br OCH₂CH(Me) H Q8a 3194. BrBr OCH₂CH(Me) H Q8d 3195. Br Br OCH₂CH(Me) H Q9a 3196. Br Br OCH₂CH(Me)H Q12 3197. Br Br OCH₂CH(Me) H Q13 3198. Br Br OCH₂CH(Me) Me Q1a 3199.Br Br OCH₂CH(Me) Me Q3a 3200. Br Br OCH₂CH(Me) Me Q6a 3201. Br BrOCH₂CH₂CH₂ H Q1a 3202. Br Br OCH₂CH₂CH₂ H Q1b 3203. Br Br OCH₂CH₂CH₂ HQ1c 3204. Br Br OCH₂CH₂CH₂ H Q1d 3205. Br Br OCH₂CH₂CH₂ H Q1e 3206. BrBr OCH₂CH₂CH₂ H Q2a 3207. Br Br OCH₂CH₂CH₂ H Q2b 3208. Br Br OCH₂CH₂CH₂H Q3a 3209. Br Br OCH₂CH₂CH₂ H Q3c 3210. Br Br OCH₂CH₂CH₂ H Q4a 3211. BrBr OCH₂CH₂CH₂ H Q5a 3212. Br Br OCH₂CH₂CH₂ H Q6a 3213. Br Br OCH₂CH₂CH₂H Q8a 3214. Br Br OCH₂CH₂CH₂ H Q8d 3215. Br Br OCH₂CH₂CH₂ H Q9a 3216. BrBr OCH₂CH₂CH₂ H Q12 3217. Br Br OCH₂CH₂CH₂ H Q13 3218. Br Br OCH₂CH₂CH₂Me Q1a 3219. Br Br OCH₂CH₂CH₂ Me Q3a 3220. Br Br OCH₂CH₂CH₂ Me Q6a 3221.Br Br CH(Me) H Q1a 3222. Br Br CH(Me)CH₂ H Q1a 3223. Br Br OCH₂ H Q1a3224. Br Br OCH(Me)CH₂ H Q1a 3225. Br Br(Me) OCH₂CH₂ H Q1a 3226. BrBr(Me) OCH₂CH₂ H Q2a 3227. Br Br(Me) OCH₂CH₂ H Q2b 3228. Br Br(Me)OCH₂CH₂ H Q3a 3229. Br Br(Me) OCH₂CH₂ H Q6a 3230. Br Br(Me) OCH₂CH₂ HQ8d 3231. Br Br(Me) OCH₂CH₂ Me Q1a 3232. Br Br(Me) OCH₂CH₂ Me Q2a 3233.Br Br(Me) OCH₂CH₂ Me Q2b 3234. Br Br(Me) OCH₂CH₂ Me Q3a 3235. Br Br(Me)OCH₂CH₂ Me Q6a 3236. Br Br(Me) OCH₂CH₂ Me Q8d 3237. Br I OCH₂CH₂ H Q1a3238. Br I OCH₂CH₂ H Q2a 3239. Br I OCH₂CH₂ H Q2b 3240. Br I OCH₂CH₂ HQ3a 3241. Br I OCH₂CH₂ H Q6a 3242. Br I OCH₂CH₂ H Q8d 3243. Br I OCH₂CH₂Me Q1a 3244. Br I OCH₂CH₂ Me Q2a 3245. Br I OCH₂CH₂ Me Q2b 3246. Br IOCH₂CH₂ Me Q6a 3247. Br I OCH(Me)CH₂ H Q1a 3248. Br I OCH₂CH₂CH₂ H Q1a3249. Br Me OCH₂CH₂ H Q1a 3250. Br Me OCH₂CH₂ H Q1b 3251. Br Me OCH₂CH₂H Q1c 3252. Br Me OCH₂CH₂ H Q1d 3253. Br Me OCH₂CH₂ H Q1e 3254. Br MeOCH₂CH₂ H Q2a 3255. Br Me OCH₂CH₂ H Q2b 3256. Br Me OCH₂CH₂ H Q3a 3257.Br Me OCH₂CH₂ H Q3c 3258. Br Me OCH₂CH₂ H Q4a 3259. Br Me OCH₂CH₂ H Q5a3260. Br Me OCH₂CH₂ H Q6a 3261. Br Me OCH₂CH₂ H Q8a 3262. Br Me OCH₂CH₂H Q8d 3263. Br Me OCH₂CH₂ H Q9a 3264. Br Me OCH₂CH₂ H Q12 3265. Br MeOCH₂CH₂ H Q13 3266. Br Me OCH₂CH₂ Me Q1a 3267. Br Me OCH₂CH₂ Me Q2a3268. Br Me OCH₂CH₂ Me Q2b 3269. Br Me OCH₂CH₂ Me Q3a 3270. Br MeOCH₂CH₂ Me Q6a 3271. Br Me OCH₂CH₂ Me Q8d 3272. Br Me OCH₂CH(Me) H Q1a3273. Br Me OCH₂CH₂CH₂ H Q1a 3274. Br CN OCH₂CH₂ H Q1a 3275. Br CNOCH₂CH₂ H Q3a 3276. Br CN OCH₂CH₂ H Q4a 3277. Br CN OCH₂CH₂ Me Q1a 3278.Br CN OCH₂CH₂ Me Q3a 3279. Br CN OCH₂CH₂ Me Q4a 3280. Br CF3 OCH₂CH₂ HQ1a 3281. Br CF3 OCH₂CH₂ H Q2a 3282. Br CF3 OCH₂CH₂ H Q2b 3283. Br CF3OCH₂CH₂ H Q3a 3284. Br CF3 OCH₂CH₂ Me Q1a 3285. Br CF3 OCH₂CH₂ Me Q3a3286. Br CF3 OCH₂CH₂CH₂ H Q1a 3287. Br CF3 OCH₂CH₂CH₂ Me Q1a 3288. BrSO₂Me CH₂ H Q1a 3289. Br SO₂Me CH₂ H Q1b 3290. Br SO₂Me CH₂ H Q1c 3291.Br SO₂Me CH₂ H Q1d 3292. Br SO₂Me CH₂ H Q1e 3293. Br SO₂Me CH₂ H Q2a3294. Br SO₂Me CH₂ H Q2b 3295. Br SO₂Me CH₂ H Q3a 3296. Br SO₂Me CH₂ HQ3c 3297. Br SO₂Me CH₂ H Q4a 3298. Br SO₂Me CH₂ H Q5a 3299. Br SO₂Me CH₂H Q6a 3300. Br SO₂Me CH₂ H Q8a 3301. Br SO₂Me CH₂ H Q8d 3302. Br SO₂MeCH₂ H Q9a 3303. Br SO₂Me CH₂ H Q12 3304. Br SO₂Me CH₂ H Q13 3305. BrSO₂Me CH₂ Me Q1a 3306. Br SO₂Me CH₂ Me Q2a 3307. Br SO₂Me CH₂ Me Q2b3308. Br SO₂Me CH₂ Me Q3a 3309. Br SO₂Me CH₂ Me Q6a 3310. Br SO₂Me CH₂Me Q8d 3311. Br SO₂Me CH₂ Et Q1a 3312. Br SO₂Me CH₂ n-Pr Q1a 3313. BrSO₂Me CH₂ SMe Q1a 3314. Br SO₂Me CH₂CH₂ H Q1a 3315. Br SO₂Me CH₂CH₂ MeQ1a 3316. Br SO₂Me OCH₂CH₂ H Q1a 3317. Br SO₂Me OCH₂CH₂ H Q1b 3318. BrSO₂Me OCH₂CH₂ H Q1c 3319. Br SO₂Me OCH₂CH₂ H Q1d 3320. Br SO₂Me OCH₂CH₂H Q1e 3321. Br SO₂Me OCH₂CH₂ H Q2a 3322. Br SO₂Me OCH₂CH₂ H Q2b 3323. BrSO₂Me OCH₂CH₂ H Q3a 3324. Br SO₂Me OCH₂CH₂ H Q3c 3325. Br SO₂Me OCH₂CH₂H Q4a 3326. Br SO₂Me OCH₂CH₂ H Q5a 3327. Br SO₂Me OCH₂CH₂ H Q6a 3328. BrSO₂Me OCH₂CH₂ H Q8a 3329. Br SO₂Me OCH₂CH₂ H Q8d 3330. Br SO₂Me OCH₂CH₂H Q9a 3331. Br SO₂Me OCH₂CH₂ H Q12 3332. Br SO₂Me OCH₂CH₂ H Q13 3333. BrSO₂Me OCH₂CH₂ Me Q1a 3334. Br SO₂Me OCH₂CH₂ Me Q2a 3335. Br SO₂MeOCH₂CH₂ Me Q2b 3336. Br SO₂Me OCH₂CH₂ Me Q3a 3337. Br SO₂Me OCH₂CH₂ MeQ6a 3338. Br SO₂Me OCH₂CH₂ Me Q8d 3339. Br SO₂Me OCH₂CH₂ Et Q1a 3340. BrSO₂Me OCH₂CH₂ n-Pr Q1a 3341. Br SO₂Me OCH₂CH₂ SMe Q1a 3342. Br SO₂MeOCH₂CH(Me) H Q1a 3343. Br SO₂Me OCH₂CH₂CH₂ H Q1a 3344. Br SO₂MeOCH₂CH₂CH₂ Me Q1a 3345. I I OCH₂CH₂ H Q1a 3346. I I OCH₂CH₂ H Q2a 3347.I I OCH₂CH₂ H Q2b 3348. I I OCH₂CH₂ H Q3a 3349. I I OCH₂CH₂ H Q6a 3350.I I OCH₂CH₂ H Q8d 3351. I I OCH₂CH₂ Me Q1a 3352. I I OCH₂CH₂ Me Q3a3353. I I OCH₂CH₂ Me Q6a 3354. I I OCH₂CH₂(Me) H Q1a 3355. I IOCH₂CH₂CH₂ H Q1a 3356. Me Cl OCH₂CH₂ H Q1a 3357. Me Cl OCH₂CH₂ H Q1b3358. Me Cl OCH₂CH₂ H Q1c 3359. Me Cl OCH₂CH₂ H Q1d 3360. Me Cl OCH₂CH₂H Q1e 3361. Me Cl OCH₂CH₂ H Q2a 3362. Me Cl OCH₂CH₂ H Q2b 3363. Me ClOCH₂CH₂ H Q3a 3364. Me Cl OCH₂CH₂ H Q3c 3365. Me Cl OCH₂CH₂ H Q4a 3366.Me Cl OCH₂CH₂ H Q5a 3367. Me Cl OCH₂CH₂ H Q6a 3368. Me Cl OCH₂CH₂ H Q8a3369. Me Cl OCH₂CH₂ H Q8d 3370. Me Cl OCH₂CH₂ H Q9a 3371. Me Cl OCH₂CH₂H Q12 3372. Me Cl OCH₂CH₂ H Q13 3373. Me Cl OCH₂CH₂ Me Q1a 3374. Me ClOCH₂CH₂ Me Q2a 3375. Me Cl OCH₂CH₂ Me Q2b 3376. Me Cl OCH₂CH₂ Me Q3a3377. Me Cl OCH₂CH₂ Me Q6a 3378. Me Cl OCH₂CH₂ Me Q8d 3379. Me ClOCH₂CH₂(Me) H Q1a 3380. Me Cl OCH₂CH₂CH₂ H Q1a 3381. Me Br OCH₂CH₂ H Q1a1.5475 3382. Me Br OCH₂CH₂ H Q1b 3383. Me Br OCH₂CH₂ H Q1c 3384. Me BrOCH₂CH₂ H Q1d 3385. Me Br OCH₂CH₂ H Q1e 3386. Me Br OCH₂CH₂ H Q2a 1.59153387. Me Br OCH₂CH₂ H Q2b 3388. Me Br OCH₂CH₂ H Q3a 1.6328 3389. Me BrOCH₂CH₂ H Q3c 3390. Me Br OCH₂CH₂ H Q4a 3391. Me Br OCH₂CH₂ H Q5a 3392.Me Br OCH₂CH₂ H Q6a 3393. Me Br OCH₂CH₂ H Q8a 3394. Me Br OCH₂CH₂ H Q8d3395. Me Br OCH₂CH₂ H Q9a 3396. Me Br OCH₂CH₂ H Q12 3397. Me Br OCH₂CH₂H Q13 1.5688 3398. Me Br OCH₂CH₂ Me Q1a 1.5692 3399. Me Br OCH₂CH₂ MeQ2a 3400. Me Br OCH₂CH₂ Me Q2b 3401. Me Br OCH₂CH₂ Me Q3a 3402. Me BrOCH₂CH₂ Me Q6a 3403. Me Br OCH₂CH₂ Me Q8d 3404. Me Br OCH₂CH(Me) H Q1a3405. Me Br OCH₂CH₂CH₂ H Q1a 3406. Me I OCH₂CH₂ H Q1a 3407. Me I OCH₂CH₂H Q3a 3408. Me 1 OCH₂CH₂ H Q6a 3409. Me I OCH₂CH₂ H Q8d 3410. Me IOCH₂CH₂ Me Q1a 3411. Me I OCH₂CH₂ Me Q3a 3412. Me I OCH₂CH₂ Me Q6a 3413.Me I OCH₂CH(Me) H Q1a 3414. Me I OCH₂CH₂CH₂ H Q1a 3415. Me SMe OCH₂CH₂ HQ1a 3416. Me SMe OCH₂CH₂ H Q3a 3417. Me SMe OCH₂CH₂ H Q6a 3418. Me SMeOCH₂CH₂ H Q8d 3419. Me SMe OCH₂CH₂ Me Q1a 3420. Me SMe OCH₂CH₂ Me Q3a3421. Me SMe OCH₂CH₂ Me Q6a 3422. Me SMe OCH₂CH(Me) H Q1a 3423. Me SMeOCH₂CH₂CH₂ H Q1a 3424. Me SO₂Me CH₂ H Q1a 3425. Me SO₂Me CH₂ H Q1b 3426.Me SO₂Me CH₂ H Q1c 3427. Me SO₂Me CH₂ H Q1d 3428. Me SO₂Me CH₂ H Q1e3429. Me SO₂Me CH₂ H Q2a 3430. Me SO₂Me CH₂ H Q2b 3431. Me SO₂Me CH₂ HQ3a 3432. Me SO₂Me CH₂ H Q3c 3433. Me SO₂Me CH₂ H Q4a 3434. Me SO₂Me CH₂H Q5a 3435. Me SO₂Me CH₂ H Q6a 3436. Me SO₂Me CH₂ H Q8a 3437. Me SO₂MeCH₂ H Q8d 3438. Me SO₂Me CH₂ H Q9a 3439. Me SO₂Me CH₂ H Q12 3440. MeSO₂Me CH₂ H Q13 3441. Me SO₂Me CH₂ Me Q1a 3442. Me SO₂Me CH₂ Me Q2a3443. Me SO₂Me CH₂ Me Q2b 3444. Me SO₂Me CH₂ Me Q3a 3445. Me SO₂Me CH₂Me Q6a 3446. Me SO₂Me CH₂ Me Q8d 3447. Me SO₂Me CH₂ Et Q1a 3448. MeSO₂Me CH₂ n-Pr Q1a 3449. Me SO₂Me CH₂ SMe Q1a 3450. Me SO₂Me CH₂CH₂ HQ1a 3451. Me SO₂Me CH₂CH₂ Me Q1a 3452. Me SO₂Me OCH₂CH₂ H Q1a 3453. MeSO₂Me OCH₂CH₂ H Q1b 3454. Me SO₂Me OCH₂CH₂ H Q1c 3455. Me SO₂Me OCH₂CH₂H Q1d 3456. Me SO₂Me OCH₂CH₂ H Q1e 3457. Me SO₂Me OCH₂CH₂ H Q2a 3458. MeSO₂Me OCH₂CH₂ H Q2b 3459. Me SO₂Me OCH₂CH₂ H Q3a 3460. Me SO₂Me OCH₂CH₂H Q3c 3461. Me SO₂Me OCH₂CH₂ H Q4a 3462. Me SO₂Me OCH₂CH₂ H Q5a 3463. MeSO₂Me OCH₂CH₂ H Q6a 3464. Me SO₂Me OCH₂CH₂ H Q8a 3465. Me SO₂Me OCH₂CH₂H Q8d 3466. Me SO₂Me OCH₂CH₂ H Q9a 3467. Me SO₂Me OCH₂CH₂ H Q12 3468. MeSO₂Me OCH₂CH₂ H Q13 3469. Me SO₂Me OCH₂CH₂ Me Q1a 3470. Me SO₂Me OCH₂CH₂Me Q2a 3471. Me SO₂Me OCH₂CH₂ Me Q2b 3472. Me SO₂Me OCH₂CH₂ Me Q3a 3473.Me SO₂Me OCH₂CH₂ Me Q6a 3474. Me SO₂Me OCH₂CH₂ Me Q8d 3475. Me SO₂MeOCH₂CH₂ Et Q1a 3476. Me SO₂Me OCH₂CH₂ n-Pr Q1a 3477. Me SO₂Me OCH₂CH₂SMe Q1a 3478. Me SO₂Me OCH₂CH(Me) H Q1a 3479. Me SO₂Me OCH₂CH₂CH₂ H Q1a3480. Me SO₂Me OCH₂CH₂CH₂ Me Q1a 3481. Me NO₂ OCH₂CH₂ H Q1a 3482. Me NO₂OClI2CH₂ H Q1b 3483. Me NO₂ OCH₂CH₂ H Q1c 3484. Me NO₂ OCH₂CH₂ H Q1d3485. Me NO₂ OCH₂CH₂ H Q1e 3486. Me NO₂ OCH₂CH₂ H Q2a 3487. Me NO₂OCH₂CH₂ H Q2b 3488. Me NO₂ OCH₂CH₂ H Q3a 3489. Me NO₂ OCH₂CH₂ H Q3c3490. Me NO₂ OCH₂CH₂ H Q4a 3491. Me NO₂ OCH₂CH₂ H Q5a 3492. Me NO₂OCH₂CH₂ H Q6a 3493. Me NO₂ OCH₂CH₂ H Q8a 3494. Me NO₂ OCH₂CH₂ H Q8d3495. Me NO₂ OCH₂CH₂ H Q9a 3496. Me NO₂ OCH₂CH₂ H Q12 3497. Me NO₂OCH₂CH₂ H Q13 3498. Me NO₂ OCH₂CH₂ Me Q1a 3499. Me NO₂ OCH₂CH₂ Me Q2a3500. Me NO₂ OCH₂CH₂ Me Q2b 3501. Me NO₂ OCH₂CH₂ Me Q3a 3502. Me NO₂OCH₂CH₂ Me Q6a 3503. Me NO₂ OCH₂CH₂ Me Q8d 3504. Me NO₂ OCH₂CH₂ Et Q1a3505. Me NO₂ OCH₂CH₂ n-Pr Q1a 3506. Me NO₂ OCH₂CH₂ SMe Q1a 3507. Me NO₂OCH₂CH(Me) H Q1a 3508. Me NO₂ OCH₂CH₂CH₂ H Q1a 3509. Me NO₂ OCH₂CH₂CH₂Me Q1a 3510. OMe Cl CH₂ H Q1a 3511. OMe Cl CH₂ H Q3a 3512. OMe Cl CH₂ HQ8d 3513. OMe Cl CH₂ Me Q1a 3514. OMe Cl CH₂ Me Q3a 3515. OMe Cl CH₂ MeQ8d 3516. SMe Cl OCH₂CH₂ H Q1a 3517. SMe Cl OCH₂CH₂ H Q3a 3518. SMe ClOCH₂CH₂ H Q8d 3519. SMe Cl OCH₂CH₂ Me Q1a 3520. SMe Cl OCH₂CH₂ Me Q3a3521. SMe Cl OCH₂CH₂ Me Q8d 3522. SMe SMe CH₂ H Q1a 3523. SMe SMe CH₂ HQ3a 3524. SO₂Me Cl OCH₂CH₂ H Q1a 3525. SO₂Me Cl OCH₂CH₂ H Q3a 3526.SO₂Me Cl OCH₂CH₂ H Q8d 3527. SO₂Me Cl OCH₂CH₂ Me Q1a 3528. SO₂Me ClOCH₂CH₂ Me Q3a 3529. SO₂Me Cl OCH₂CH₂ Me Q8d 3530. NO₂ Me OCH₂CH₂ H Q1a3531. NO₂ Me OCH₂CH₂ H Q3a 3532. NO₂ Me OCH₂CH₂ H Q8d 3533. NO₂ MeOCH₂CH₂ Me Q1a 3534. NO₂ Me OCH₂CH₂ Me Q3a 3535. NO₂ Me OCH₂CH₂ Me Q8d3536. NO₂ CH₂OMe OCH₂CH₂ H Q1a 3537. NO₂ CH₂SMe OCH₂CH₂ H Q1a 3538. NO₂CH₂SO₂Me OCH₂CH₂ H Q1a 3539. CN Me OCH₂CH₂ H Q1a 3540. CN Me OCH₂CH₂ HQ3a 3541. CN Me OCH₂CH₂ H Q8d 3542. CN Me OCH₂CH₂ Me Q1a 3543. CN MeOCH₂CH₂ Me Q3a 3544. CN Me OCH₂CH₂ Me Q8d 3545. Cl Cl CH₂ H Q4e 3546. ClCl CH₂ H Q4f 3547. Cl Cl CH₂ H Q4g 3548. Cl Cl CH₂ H Q10b 3549. Cl ClCH₂ H Q16 3550. Cl Cl CH₂ H Q22 3551. Cl Cl OCH₂CH₂ H Q4e 3552. Cl ClOCH₂CH₂ H Q4f 3553. Cl Cl OCH₂CH₂ H Q4g 3554. Cl Cl OCH₂CH₂ H Q4h 3555.Cl Cl OCH₂CH₂ H Q4i 3556. Cl Cl OCH₂CH₂ H Q4j 3557. Cl Cl OCH₂CH₂ H Q10b3558. Cl Cl OCH₂CH₂ H Q10c 3559. Cl Cl OCH₂CH₂ H Q10d 3560. Cl ClOCH₂CH₂ H Q1Qe 3561. Cl Cl OCH₂CH₂ H Q10f 3562. Cl Cl OCH₂CH₂ H Q163563. Cl Cl OCH₂CH₂ H Q17 3564. Cl Cl OCH₂CH₂ H Q18 3565. Cl Cl OCH₂CH₂H Q19 3566. Cl Cl OCH₂CH₂ H Q20 3567. Cl Cl OCH₂CH₂ H Q21 3568. Cl ClOCH₂CH₂ H Q22 3569. Cl Cl OCH₂CH₂ H Q23 3570. Cl Cl OCH₂CH₂ H Q24 3571.Cl Cl OCH₂CH₂ H Q25 3572. Cl Cl OCH₂CH₂ H Q26 3573. Cl Cl OCH₂CH₂ Me Q4e3574. Cl Cl OCH₂CH₂ Me Q4f 3575. Cl Cl OCH₂CH₂ Me Q10b 3576. Cl ClOCH₂CH₂ Me Q16 3577. Cl Cl OCH₂CH₂ Me Q19 3578. Cl Cl OCH₂CH₂ Me Q223579. Cl SO₂Me CH₂ H Q4e 3580. Cl SO₂Me CH₂ H Q4f 3581. Cl SO₂Me Cl2 HQ4g 3582. Cl SO₂Me CH₂ H Q4h 3583. Cl SO₂Me CH₂ H Q4i 3584. Cl SO₂Me CH₂H Q4j 3585. Cl SO₂Me CH₂ H Q10b 3586. Cl SO₂Me CH₂ H Q10c 3587. Cl SO₂MeCH₂ H Q10d 3588. Cl SO₂Me CH₂ H Q10e 3589. Cl SO₂Me CH₂ H Q10f 3590. ClSO₂Me CH₂ H Q1lb 3591. Cl SO₂Me CH₂ H Q1lc 3592. Cl SO₂Me CH₂ H Q1ld3593. Cl SO₂Me CH₂ H Q16 3594. Cl SO₂Me CH₂ H Q17 3595. Cl SO₂Me CH₂ HQ15 3596. Cl SO₂Me CH₂ H Q19 3597. Cl SO₂Me CH₂ H Q20 3598. Cl SO₂Me CH₂H Q21 3599. Cl SO₂Me CH₂ H Q22 3600. Cl SO₂Me CH₂ H Q23 3601. Cl SO₂MeCH₂ H Q24 3602. Cl SO₂Me CH₂ H Q25 3603. Cl SO₂Me CH₂ H Q26 3604. ClSO₂Me CH₂ Me Q4e 3605. Cl SO₂Me CH₂ Me Q4f 3606. Cl SO₂Me CH₂ Me Q10b3607. Cl SO₂Me CH₂ Me Q16 3608. Cl SO₂Me CH₂ Me Q19 3609. Cl SO₂Me CH₂Me Q22*Substituent R^(1c) is mentioned in parenthesis in the column of thegroup R^(1b), only when it is other than a hydrogen atom (H).

SYNTHESIS EXAMPLE 5 Intermediate Synthesis

2,4-Dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoic acid (0.68 g) andthionyl chloride (0.40 g) were added in 1,2-dichloroethane (20 ml) andafter addition of 2 drops of N,N-dimethylformamide the mixture wasrefluxed for 5 hours. After cooling the solvent was distilled off. Theobtained residue was dissolved in dichloromethane (10 ml) and added intoa solution of 1,3-cyclohexanedione (0.18 g) and triethylamine (0.18 g)in dichloromethane (10 ml) drop by drop at 5° C. and the mixture wasstirred at room temperature for 6 hours. After the reaction it wasextracted with dichloromethane (100 ml), washed with dilutedhydrochloric acid and an aqueous solution of sodium hydrogen carbonateand dried with anhydrous magnesium sulfate. After dichloromethane wasdistilled off, the obtained residue was purified by silica gel columnchromatography (eluent:ethyl acetate:hexane=3:2) to obtain the objective3-oxo-1-cyclohexenyl 2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoate(0.51 g).

n^(D) ₂₀: 1.5835.

SYNTHESIS EXAMPLE 6 Intermediate Synthesis

2,4-Dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoic acid (0.46 g) andthionyl chloride (0.36 g) were added in 1,2-dichloroethane (10 ml) andafter addition of 2 drops of N,N-dimethylformamide the mixture wasrefluxed for 5 hours. After cooling the solvent was distilled off. Theobtained residue was dissolved in dichloromethane (5 ml) and added intoa solution of 1-ethyl-5-hydroxypyrazole (0.18 g) and triethylamine (0.19g) in dichloromethane (5 ml) drop by drop at 5° C. and the mixture wasstirred at room temperature for 6 hours. After the reaction it wasextracted with dichloromethane (100 ml), washed with dilutedhydrochloric acid and an aqueous solution of sodium hydrogen carbonateand dried with anhydrous magnesium sulfate. Dichloromethane wasdistilled off to obtain the objective5-{2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoyloxy}-1-ethylpyrazole(0.58 g) (viscous oily substance), which was used as the intermediatefor preparation in the aforementioned Synthesis Example 4.

SYNTHESIS EXAMPLE 7 Intermediate Synthesis

In N,N-dimethylformamide (15 ml) 1H-tetrazole (0.45 g) and ethyl3-(2-bromo-ethoxy)-2,4-dichlorobenzoate (2.00 g) were suspended andpotassium carbonate (1.21 g) and sodium iodide (0.04 g) were addedthereto and the mixture was stirred at 80° C. for 3 hours. After thereaction cold water was added to the mixture and it was extracted withethyl acetate (100 ml) and dried with anhydrous magnesium sulfate. Afterethyl acetate was distilled off, the obtained residue was purified bysilica gel column chromatography (eluent:ethyl acetate:hexane=1:1) toobtain the objective ethyl2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoate (0.88 g, n^(D) ₂₀:1.5535) and ethyl 2,4-dichloro-3-[2-(1H-tetrazol-2-yl)ethoxy]benzoate(0.99 g), n^(D) ₂₀: 1.5483.

SYNTHESIS EXAMPLE 8 Intermediate Synthesis

To a solution of ethyl2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoate (0.88 g) in methanol(15 ml) sodium hydroxide (0.16 g) and water (5 ml) were added and themixture was stirred at room temperature for 7 hours. After addition ofwater (20 ml) and concentration under reduced pressure, an aqueoussolution of sodium hydroxide was added and washed with ethyl acetate (50ml). The aqueous layer was acidified with hydrochloric acid andextracted with ethyl acetate. The organic layer was washed withsaturated aqueous solution of sodium chloride and dried with anhydrousmagnesium sulfate. Ethyl acetate was distilled off to obtain theobjective 2,4-dichloro-3-[2-(1H-tetrazol-1-yl)ethoxy]benzoic acid (0.69g).

Mp: 145-146° C.

Biological Tests

EXAMPLE 1 Test for Herbicidal Effect Against Paddy Field Weeds

Preparation of formulation of the active compound

-   -   Carrier: Acetone 5 parts by weight    -   Emulsifier: Benzyloxy polyglycol ether 1 part by weight

A formulation of an active substance is obtained as an emulsifiableconcentrate by mixing 1 part by weight of the active compound with theabove-mentioned amount of the carrier and emulsifier. A prescribedamount of the formulation is diluted with water.

Test Method

In a green house 3 seedlings of paddy rice (variety: Nihonbare) of 2.5leaf stage (15 cm tall) were transplanted in a 500 cm² pot filled withpaddy field soil. Then seeds or tubers of Echinochloa crusgalli, Cyperusdifformis L., Scirpus juncoides Roxburgh, Monochoria vaginalis Presl,broad-leaved weeds (Lindernia Procumbens Philcox, Rotala indica Koehne,Elatine triandra Schk, Ammannia multiflora Roxb., Dopatrium junceumHammilt etc.), Cyperus serotinus Rottboel and Sagittaria pygmaea Miqwere inoculated and water was poured to a depth of about 2-3 cm. 5 daysafter the rice transplantation a prescribed, diluted solution of eachformulation of active compound prepared according to the aforementionedpreparation method was applied to the surface of water. After thetreatment the water depth of 3 cm was maintained and the herbicidaleffect was examined after 3 weeks from the treatment. The herbicidaleffect was rated 100% in the case of complete death and as 0% in thecase of no herbicidal effect.

Results

As a result, as specific examples the compounds No. 217, 219, 558, 1838,2024, 2329, 2335 and 2364 showed a sufficient herbicidal effect againstpaddy field weeds at the chemical amount (amount of the activecomponent) of 0.25 kg/ha and a safety to the transplanted paddy rice.

EXAMPLE 2 Test of Pre-Emergence Soil Treatment Against Field Weeds

Test Method

In a green house, on the surface layer of a 120 cm² pot filled withfield soil, seeds of Echinochloa crusgalli, Setaria viridis, Amaranthusretroflexus and Polygonum were sown and covered with soil. A dilutedsolution of the prescribed chemical amount prepared in the same manneras in the above-mentioned Test Example 1 was spread uniformly on thesoil surface layer of each test pot. The herbicidal effect was examined4 weeks after the treatment.

Results

As a result, as specific examples the compounds No. 213, 215, 258, 272,275, 278, 715, 1234, 1239, 1593, 2077, 2080, 2081, 2301, 2347, 2521 and3043 showed a herbicidal activity of higher than 90% against Echinochloacrusgalli, Setaria viridis, Amaranthus retroflexus and Polygonum at thechemical amount (amount of the active component) of 2.0 kg/ha.

EXAMPLE 3 Test of Post-Emergence Foliage Treatment Against Field Weeds

Test Method

In a green house, seeds of Echinochloa crusgalli, Setaria viridis,Amaranthus retro-flexus and Polygonum were sown in a 120 cm² pot filledwith field soil and covered with soil. 10 days after the sowing and soilcovering (weeds were 2-leaf stage in average) a diluted solution of theprescribed chemical amount prepared in the same manner as in theabove-mentioned Test Example 1 was spread uniformly on the foliage ofthe test plants in each test pot. The herbicidal effect was examined 3weeks after the treatment.

Results

As a result, as specific examples the compounds No. 212, 213, 215, 258,272, 275, 355, 495, 650, 715, 1234, 1239, 1593, 1693, 2017, 2022, 2063,2077, 2080, 2081, 2301, 2347, 2364, 2521, 3038 and 3043 showed aherbicidal activity of 90% against Echinochloa crusgalli, Setariaviridis, Amaranthus retroflexus and Polygonum at the chemical amount(amount of the effective component) of 2.0 kg/ha.

Formulations

EXAMPLE 1 Granule

To a mixture of the compound of the present invention No. 2024 (10parts), bentonite (montmorillonite) (30 parts), talc (58 parts) andligninsulfonate salt (2 parts), water (25 parts) were added, wellkneaded, made into granules of 10-40 mesh by an extrusion granulator anddried at 40-50° C. to obtain granules.

EXAMPLE 2 Granule

Clay mineral particles (95 parts) having particle diameter distributionin the range of 0.2-2 mm are put in a rotary mixer. While rotating it,the compound of the present invention No. 217 (5 parts) are sprayedtogether with a liquid diluent, wetted uniformly and dried at 40-50° C.to obtain granules.

EXAMPLE 3 Emulsifiable Concentrate

The compound of the present invention No. 212 (30 parts), xylene (5parts), polyoxyethylene alkyl phenyl ether (8 parts) and calciumalkylbenzenesulfonate (7 parts) are mixed and stirred to obtain anemulsifiable concentrate.

EXAMPLE 4 Wettable Powder

The compound of the present invention No. 258 (15 Parts), a mixture ofwhite carbon (hydrous amorphous silicon oxide fine powders) and powderclay (1:5) (80 parts), sodium alkylbenzenesulfonate (2 parts) and sodiumalkylnaphthalenesulfonate-formalin-condensate (3 parts) are crushed andmixed to make a wettable powder.

EXAMPLE 5 Water Dispersible Granule

The compound of the present invention No. 258 (20 Parts), sodiumligninsulfonate (30 parts), bentonite (15 parts) and calcineddiatomaceous earth (35 parts) are well mixed, added with water, extrudedwith 0.3 mm screen and dried to obtain water dispersible granules.

1) Compounds of formula (I)

wherein R¹ represents halogen, alkyl, haloalkyl, alkoxy, alkylthio,alkylsulfonyl, alkylsulfonyloxy, alkoxyalkyl, alkylthioalkyl,alkylsulfonylalkyl, nitro or cyano, m represents 0, 1, 2 or 3, R¹ may beidentical or different to each other, when m represents 2 or 3, nrepresents 0 or 1, A represents alkylene, T represents a group

in which R² represents hydrogen, alkyl or cycloalkyl, which may beoptionally substituted by alogen and alkyl, or represents alkenyl,alkynyl, haloalkyl, alkylthio, or phenyl which may be optionallysubstituted by halogen, alkyl, haloalkyl and nitro, and Q represents agroup

wherein R³ represents hydroxy, halogen or alkylcarbonyloxy, orrepresents alkylthio which may be optionally substituted by hydroxy,cyano, carboxy, alkoxycarbonyl and phenyl, or represents 5- or6-membered heteroarylthio containing 1-2 hetero atom(s) selected fromthe group consisting of nitrogen, oxygen and sulfur, which may beoptionally substituted by halogen and alkyl, and when R³ representspyridylthio, said pyridylthio may form N-oxide, or represents phenylthiowhich may be optionally substituted by halogen, alkyl, alkoxy, haloalkyland nitro, or represents phenylcarbonyloxy which may be optionallysubstituted by halogen and alkyl, or represents 1-pyrazolyl which may beoptionally substituted or 1-imidazolyl which may be optionallysubstituted by halogen and alkyl, or represents 1,2,4-triazol-1-yl or1H-tetrazol-1-yl, R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ each independently representhydrogen or alkyl, or R⁴ may, together with R⁹, form an ethylene chain,R¹⁰ represents alkyl, and R¹¹ represents alkyl or cycloalkyl. 2) Thecompounds of the formula(I) according to claim 1 wherein R¹ representsfluoro, chloro, bromo, iodo, C₁₋₆ alkyl, C₁₋₆ haloalkyl, C₁₋₆ alkoxy,C₁₋₄ alkylthio, C₁₋₆ alkylsulfonyl, C₁₋₆ alkylsulfonyloxy, C₂₋₆alkoxyalkyl, C₂₋₆ alkylthioalkyl, C₂₋₆ alkylsulfonylalkyl, nitro orcyano, m represents 2 or 3, A represents C₁₋₄ alkylene, R² representshydrogen, C₁₋₆ alkyl, C₃₋₆ cycloalkyl, C₂₋₆ alkenyl, C₂₋₆ alkynyl, C₁₋₆haloalkyl, C₁₋₆ alkylthio, or phenyl which may be optionally substitutedby chloro, C₁₋₄ alkyl, C₁₋₄ haloalkyl and nitro, and R³ representshydroxy, chloro, bromo, C₂₋₅ alkylcarbonyloxy, or C₁₋₆ alkylthio whichmay be optionally substituted by hydroxy, cyano, carboxy, C₂₋₅alkoxycarbonyl and phenyl, or thienylthio, thiazolylthio, oxazolylthio,pyridylthio, 1-oxidopyridylthio or pyrimidylthio, optionally substitutedby chloro-, bromo-, or C₁-C₄ alkyl, or phenylthio which may beoptionally substituted by one or two substituents selected from thegroup consisting of fluoro, chloro, bromo, C₁₋₄ alkyl, C₁₋₄ alkoxy, C₁₋₄haloalkyl and nitro, or phenylcarbonyloxy which may be optionallysubstituted by one or two substituents selected from the groupconsisting of chloro and C₁₋₄ alkyl, or 1-pyrazolyl or 1-imidazolylwhich may be optionally substituted by one or two substituents selectedfrom the group consisting of chloro, bromo and C₁₋₄ alkyl, or1,2,4-triazol-1-yl or 1H-tetrazol-1-yl, R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ eachindependently preferably represent hydrogen or C₁₋₄ alkyl, or R⁴ may,together with R⁹, form an ethylene chain, R¹⁰ preferably represents C₁₋₄alkyl, R¹¹ preferably represents C₃₋₆ cycloalkyl. R¹ particularlypreferably represents chloro, bromo, methyl, trifluoromethyl, methoxy,methylthio, ethylthio, methylsulfonyl, ethylsulfonyl, n-propylsulfonyl,methylsulfonyloxy, methoxymethyl, methylthiomethyl,methylsulfonylmethyl, nitro or cyano. 3) The compounds of the formula(I) according to claims 1 or 2 wherein m represents 2, A represents C₁₋₄alkylene, R² represents hydrogen, methyl, ethyl, n-propyl, cyclopropyl,cyclopentyl, vinyl, allyl, ethynyl, trifluoromethyl, 2-chloroethyl,3-bromopropyl, methylthio, ethylthio, n-propylthio, or phenyl which maybe optionally substituted by chloro, methyl, ethyl, n-propyl,trifluoromethyl and nitro, and R³ represents hydroxy, chloro, acetoxy,tert-butylcarbonyloxy, methylthio, ethylthio, n-propylthio,2-hydroxyethylthio, 2-cyanoethylthio, carboxymethylthio,methoxycarbonylmethylthio, 2-(ethoxycarbonyl)ethylthio, benzylthio, or2-thienylthio, 2-thiazolylthio, 2-oxazolylthio, 2-pyridylthio,1-oxido-2-pyridylthio or 2-pyrimidylthio, optionally substituted by oneor more substituents selected from the group consisting of chloro andmethyl, or phenylthio which may be optionally substituted by asubstituent selected from the group consisting of fluoro, chloro,methyl, ethyl, n-propyl, methoxy, trifluoromethyl and nitro, orrepresents phenylcarbonyloxy which may be optionally substituted by asubstituent selected from the group consisting of chloro and methyl, orrepresents1-pyrazolyl or 1-imidazolyl which may be optionallysubstituted by one or two substituents selected from the groupconsisting of chloro and methyl, or represents 1,2,4-triazol-1-yl or1H-tetrazol-1-yl, R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ each independently,represent hydrogen or methyl, or R⁴ may, together with R⁹, form anethylene chain, R¹⁰ represents methyl or ethyl, R¹¹ particularlypreferably represents cyclopropyl. 4) Process for preparing compoundsaccording to claim 1, 2 or 3 characterized in that b) in case ofpreparing a compound of the formula (I) in which Q represents the group(Q-1) and R³ represents hydroxy compounds of the formula (II)

wherein R¹, m, n, A and T have the same definition as aforementioned,and M¹ represents a group

in which R⁴, R⁵, R⁶, R⁷, R⁸, R⁹ and R¹⁰ have the same definition asaforementioned, are reacted to a rearrangement in the presence of inertsolvents, and if appropriate, in the presence of a base and a cyanide,and if appropriate, in the presence of a phase-transfer catalyst, or c)in case of preparing a compound of the formula (I) in which Q representsthe group (Q-1) and R³ represents halogen, preferably chloro or bromo:compounds of the formula (Ib)

wherein R¹, m, n, A and T have the same definition as aforementioned,and Q_(b) represents group

in which R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ have the same definition asaforementioned, are reacted with a halogenating agent in the presence ofinert solvents, or c) in case of preparing a compound of the formula (I)in which Q represents the group (Q-1) and R³ represents alkylthio whichmay be optionally substituted or represents 5- or 6-memberedheteroarylthio, or represents phenylthio which may be optionallysubstituted, or represents 1-pyrazolyl which may be optionallysubstituted or represents 1-imidazolyl which may be optionallysubstituted, or represents 1,2,4-triazol-1-yl or 1H-tetrazol-1-yl:compounds of the formula (Ic)

wherein R¹, m, n, A and T have the same definition as aforementioned,and Q_(c) represents group

in which R⁴, R⁵, R⁶, R⁷, R⁸ and R⁹ have the same definition asaforementioned, and R^(3c) represents chloro or bromo, are reacted withcompounds of the formula (III)R¹²—H   (III) wherein R¹² has the same definition as the above-mentionedR³ in the preparation process (c), in the presence of inert solvents,and if appropriate, in the presence of an acid binding agent, or e) incase of preparing a compound of the formula (I) in which Q representsthe group (Q-1) and R³ represents alkylcarbonyloxy or phenylcarbonyloxywhich may be optionally substituted: compounds of the formula (Ib)

are reacted with compounds of the formula (IV)

wherein R¹³ represents alkyl or phenyl which may be optionallysubstituted, and Hal represents halogen, preferably chloro or bromo, inthe presence of inert solvents, and if appropriate, in the presence ofan acid binding agent, or f) in case of preparing a compound of theformula (I) in which Q represents the group (Q-2): compounds of theformula (IIe)

wherein R¹, m, n, A and T have the same definition as aforementioned,and M² represents group

in which R¹⁰ has the same definition as aforementioned, are reacted to arearrangement in the presence of inert solvents, and if appropriate, inthe presence of a base, or f) in case of preparing a compound of theformula (I) in which Q represents the group (Q-3): compounds of theformula (V)

wherein R¹, m, n, A, T and R¹¹ have the same definition asaforementioned, and R¹⁴ represents C₁₋₄ alkyl, preferably methyl orethyl, are reacted with hydroxylamine in the presence of inert solvents,and if appropriate, in the presence of a base, or h) in case ofpreparing a compound of the formula (I) in which Q represents the group(Q-4): compounds of the formula (Ig)

wherein R¹, m, n, A, T and R¹¹ have the same definition asaforementioned, are subject to a ring—opening reaction in the presenceof inert solvents, and if appropriate, in the presence of a base. 5)Herbicidal compositions, characterized in that they contain at least onecompound of the formula (I) according to claim
 1. 6) Process forcombating weeds, characterized in that compounds of formula (I)according to claim 1 are allowed to act on weeds and/or their habitat.7) Use of compounds of formula (I) according to claim 1 for combatingweeds. 8) Process for the preparation of herbicidal compositions,characterized in that compounds of formula (I) according to claim 1 aremixed with extenders and/or surface active agents. 9) Compounds of theformula (XVI)

wherein Z represents a group

and R¹, R⁴, R⁵, R⁶, R⁷, R⁸, R⁹, R¹⁰, R¹¹ and R¹⁴ m, n, A, T are asdefined in claim
 1. Compounds of the formula (I)

wherein T represents a group

Q represents a group

R¹, R², R³, R⁴, R⁵, R⁶, R⁷, R⁸, R^(9,) R¹⁰, R¹¹ are as defined in thedescription, m represents 0, 1, 2 or 3, n represents 0 or 1, Arepresents alkylene, processes for their preparation, theirintermediates and their use in agriculture are described.